Anti-SIGIRR

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-EK1	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-SIGIRR Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-SIGIRR"

Anti-SIGIRR Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SIGIRR from other sources has not been determined. Protein function: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. [The UniProt Consortium]

Keywords:	Anti-TIR8, Anti-SIGIRR, Anti-Toll/interleukin-1 receptor 8, Anti-Single Ig IL-1-related receptor, Anti-Single Ig IL-1R-related molecule, Anti-Single immunoglobulin domain-containing IL1R-related protein
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-EK1

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthetic peptide corresponding to 15 amino acids at the C-terminus of mouse SIGIRR.
Format:	Purified