Proteins and Enzymes

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Human Fibrinogen (PAD4 Citrullinated)
Human Fibrinogen (PAD4 Citrullinated)

Item number: Cay400076-1

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis...
Keywords: cFBG, FGA, Fibrinopeptide A, Fibrinogen alpha chain, FGB, Fibrinopeptide B, Fibrinogen beta chain, FGG, PRO2061,...
Application: WB
407.00€
Review
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Human Transferrin Rhodamine Conjugated
Human Transferrin Rhodamine Conjugated

Item number: 009-0034

Human transferrin is encoded by the TF gene and is an iron-binding blood plasma glycoprotein that controls the level of free iron in biological fluids. Human transferrin binds iron very tightly but reversibly. Human transferrin is the most important iron pool in mammals. Human transferrin has a molecular weight of...
Expressed in: Human
130.00€
Review
GDP-L-Fucose Synthase (human recombinant)
GDP-L-Fucose Synthase (human recombinant)

Item number: Cay26695-100

GDP-L-Fucose synthase, encoded by the gene TSTA3, is an NADP(H)-binding protein that catalyzes the final step in the synthesis of GDP-L-fucose from GDP-D-mannose. It converts GDP-4-keto-6-deoxy-D-mannose to GDP-L-fucose via a two-step reaction consisting of epimerization followed by NADPH-dependent reduction....
Keywords: TSTA3, SDR4E1, Protein FX, EC=1.1.1.271, GDP-L-fucose synthase, Red cell NADP(H)-binding protein,...
Application: WB
494.00€
Review
Razor(TM) TVMV Protease
Razor(TM) TVMV Protease

Item number: BM-13001-10000

Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags...
Keywords: P1 Proteinase, EC=3.4.-.-
Application: Protein cleavage, Tag removal
MW: 27,4 kD
From 172.00€
Review
CBX1 (human recombinant)
CBX1 (human recombinant)

Item number: Cay14768-100

The heterochromatin protein 1 (HP1) family, which consists of three isoforms HP1alpha (CBX5), HP1beta (CBX1), and HP1gamma (CBX3) are chromatin-associated proteins involved in gene regulation and heterochromatin formation. CBX proteins have an N-terminal chromodomain, a C-terminal chromoshadow domain (CSD), and a...
Keywords: M31, CBX, CBX1, p25beta, HP1 beta, HP1Hsbeta, Modifier 1 protein, Chromobox protein homolog 1, Heterochromatin protein...
Expressed in: E.coli
MW: 48,9 kD
357.00€
Review
CBX2 chromodomain (human recombinant)
CBX2 chromodomain (human recombinant)

Item number: Cay14769-100

CBX2 is a component of the polycomb repressive complex 1 and represses protein expression. The chromodomain regions of CBX2 recognizes histone H3 trimethyl lysine 9 (H3K9me3) or trimethyl lysine 27 (H3K27me3). CBX2 knock-out mice have impaired spleen formation, T cell expansion, and inactivation of the X chromosome,...
Keywords: CBX2, Chromobox protein homolog 2
Application: Binding assays
Expressed in: E.coli
357.00€
Review
L3MBTL1 MBT domains (human recombinant, GST-tagged)
L3MBTL1 MBT domains (human recombinant, GST-tagged)

Item number: Cay14775-100

Key Features Cayman's L3MBTL1 MBT Domains TR-FRET Assay Kit (Cay-601030) was developed using L3MBTL1 MBT domains (human recombinant, GST-tagged) protein.Bulk sizes available upon request "The malignant brain tumor (MBT) domain is structurally related to chromatin binding domains, such as chromodomains, tudor...
Keywords: L3MBTL1, KIAA0681, H-l(3)mbt, L(3)mbt-like, H-l(3)mbt protein, L(3)mbt protein homolog, Lethal(3)malignant brain...
Application: Binding assays
Expressed in: E.coli
357.00€
Review
UHRF1 PHD domain (human recombinant)
UHRF1 PHD domain (human recombinant)

Item number: Cay14777-100

Recognition of epigenetic marks can be mediated by small modular protein units of ~50 amino acids called Plant Homeodomain (PHD) fingers. PHD fingers are zinc binding domains that have a Cys4-His-Cys3 motif and are found in more than 100 nuclear proteins that play a role in regulating chromatin. PHD domains often...
Keywords: hNp95, UHRF1, HuNp95, hUHRF1, ICBP90, EC=6.3.2.-, Nuclear protein 95, RING finger protein 106, Transcription factor...
Application: Binding assays
Expressed in: E.coli
MW: 35,5 kD
357.00€
Review
UHRF1 tudor-like region (human recombinant, His-tagged)
UHRF1 tudor-like region (human recombinant, His-tagged)

Item number: Cay14779-100

Tudor domains (or tudor-like regions) are small protein structural motifs of ~50 amino acids related to the "Royal Family" of methyl readers, which also includes chromo, malignant brain tumor (MBT), PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in...
Keywords: hNp95, UHRF1, HuNp95, hUHRF1, ICBP90, EC=6.3.2.-, Nuclear protein 95, RING finger protein 106, Transcription factor...
Application: Binding assays
Expressed in: E.coli
MW: 31,9 kD
357.00€
Review
HMG-CoA Reductase (human recombinant)
HMG-CoA Reductase (human recombinant)

Item number: Cay14944-250

HMG-CoA reductase (HMGR) is a highly regulated enzyme found on the endoplasmic reticulum (ER) membrane. It is bound to the ER membrane by a multi-pass 339 amino acid N-terminal transmembrane domain while the carboxy terminal catalytic region projects into the cytosol. HMGR is controlled by feedback regulation from...
Keywords: HMGCR, EC=1.1.1.34, HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Application: Enzyme activity
Origin: Human
MW: 76.5 kD
313.00€
Review
eIF4E (human recombinant)
eIF4E (human recombinant)

Item number: Cay15137-100

Eukaryotic translation is a complex biochemical process requiring several initiation factors. The first step in the initiation of mRNA translation involves binding of the small ribosomal subunit to mRNA. The central component in the recruitment of the pre-initiation complex during translation is the eukaryotic...
Keywords: Eukaryotic Translation Initiation Factor 4E, mRNA Cap-binding Protein, eIF-4F 25 kDa subunit
Application: Binding assays
Expressed in: E.coli
Origin: Human
469.00€
Review
Nicotinamide N-Methyltransferase (human recombinant)
Nicotinamide N-Methyltransferase (human recombinant)

Item number: Cay15138-100

Nicotinamide N-Methyltransferase (NNMT) methylates nicotinamide and other pyridine containing compounds. NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nitrogen N1 of nicotinamide to produce 1-methylnicotinamide (MNA) and S-adenosylhomocysteine. MNA is a messenger molecule that increases neurite...
Keywords: NNMT, EC=2.1.1.1, Nicotinamide N-methyltransferase
Application: Enzyme activity
313.00€
Review
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