Proteins and Enzymes

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Bovine Serum Albumin (Fraction  V, Protease and Immunoglobulin Free)
Bovine Serum Albumin (Fraction V, Protease and...

Item number: BSA-50

Suitable for use in protease sensitive assays such as RIA, EIA and hybridization, for use as a stabilizing agent for proteins and enzymes including dilute solutions of antibody, and for use as a blocking agent to reduce non-specific binding.
Application: Blocking
138.00€
Review
Razor(TM) TEV Protease
Razor(TM) TEV Protease

Item number: BM-13002-1000

Ready for use. Recombinant TEV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TEV protease recognizes a linear epitope of the general form E-Xaa-Xaa-Y-Xaa-Q-(G/S), with cleavage occuring between Q and G or Q and S. The most commonly used sequence is ENLYFQG. This TEV protease contains a S219V...
Application: Protein cleavage, Tag removal
MW: 28,6 kD
Purity: >95%
Format: Solution
From 172.00€
Review
Razor(TM) TVMV Protease
Razor(TM) TVMV Protease

Item number: BM-13001-10000

Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags from peptides. Affinity tags are often applied to facilitate...
Application: Protein cleavage, Tag removal
MW: 27,4 kD
Purity: >95%
Format: Solution
From 172.00€
Review
CBX1 (human recombinant)
CBX1 (human recombinant)

Item number: Cay14768-100

The heterochromatin protein 1 (HP1) family, which consists of three isoforms HP1alpha (CBX5), HP1beta (CBX1), and HP1gamma (CBX3) are chromatin-associated proteins involved in gene regulation and heterochromatin formation. CBX proteins have an N-terminal chromodomain, a C-terminal chromoshadow domain (CSD), and a hinge domain which connects the two. Extensive...
Expressed in: E.coli
MW: 48,9 kD
Purity: >95%
Format: Solution
357.00€
Review
CBX2 chromodomain (human recombinant)
CBX2 chromodomain (human recombinant)

Item number: Cay14769-100

CBX2 is a component of the polycomb repressive complex 1 and represses protein expression. The chromodomain regions of CBX2 recognizes histone H3 trimethyl lysine 9 (H3K9me3) or trimethyl lysine 27 (H3K27me3). CBX2 knock-out mice have impaired spleen formation, T cell expansion, and inactivation of the X chromosome, which can be lethal in some cases. This protein product...
Application: Binding assays
Expressed in: E.coli
Purity: >90%
Format: Solution
357.00€
Review
L3MBTL1 MBT domains (human recombinant, GST-tagged)
L3MBTL1 MBT domains (human recombinant,...

Item number: Cay14775-100

Key Features Cayman's L3MBTL1 MBT Domains TR-FRET Assay Kit (Cay-601030) was developed using L3MBTL1 MBT domains (human recombinant, GST-tagged) protein.Bulk sizes available upon request "The malignant brain tumor (MBT) domain is structurally related to chromatin binding domains, such as chromodomains, tudor domains, and PWWP-domains. MBT domain-containing proteins have a...
Application: Binding assays
Expressed in: E.coli
Purity: >90% estimated by SDS-PAGE
Format: Solution
357.00€
Review
UHRF1 PHD domain (human recombinant)
UHRF1 PHD domain (human recombinant)

Item number: Cay14777-100

Recognition of epigenetic marks can be mediated by small modular protein units of ~50 amino acids called Plant Homeodomain (PHD) fingers. PHD fingers are zinc binding domains that have a Cys4-His-Cys3 motif and are found in more than 100 nuclear proteins that play a role in regulating chromatin. PHD domains often work with other protein regions, such as bromodomains and...
Application: Binding assays
Expressed in: E.coli
MW: 35,5 kD
Purity: >95%
Format: Solution
357.00€
Review
UHRF1 tudor-like region (human recombinant, His-tagged)
UHRF1 tudor-like region (human recombinant,...

Item number: Cay14779-100

Tudor domains (or tudor-like regions) are small protein structural motifs of ~50 amino acids related to the "Royal Family" of methyl readers, which also includes chromo, malignant brain tumor (MBT), PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell...
Application: Binding assays
Expressed in: E.coli
MW: 31,9 kD
Purity: >95% estimated by SDS-PAGE
Format: Solution
357.00€
Review
HMG-CoA Reductase (human recombinant)
HMG-CoA Reductase (human recombinant)

Item number: Cay14944-250

HMG-CoA reductase (HMGR) is a highly regulated enzyme found on the endoplasmic reticulum (ER) membrane. It is bound to the ER membrane by a multi-pass 339 amino acid N-terminal transmembrane domain while the carboxy terminal catalytic region projects into the cytosol. HMGR is controlled by feedback regulation from sterols and non-sterol metabolites derived from mevalonate....
Application: Enzyme activity
Origin: Human
MW: 76.5 kD
Purity: >90% estimated by SDS-PAGE
Format: Purified
313.00€
Review
eIF4E (human recombinant)
eIF4E (human recombinant)

Item number: Cay15137-100

Eukaryotic translation is a complex biochemical process requiring several initiation factors. The first step in the initiation of mRNA translation involves binding of the small ribosomal subunit to mRNA. The central component in the recruitment of the pre-initiation complex during translation is the eukaryotic initiation factor 4F (eIF4F) complex, composed of eIF4A, eIF4E,...
Application: Binding assays
Expressed in: E.coli
Origin: Human
Purity: >90% estimated by SDS-PAGE
Format: Solution
469.00€
Review
Nicotinamide N-Methyltransferase (human recombinant)
Nicotinamide N-Methyltransferase (human...

Item number: Cay15138-100

Nicotinamide N-Methyltransferase (NNMT) methylates nicotinamide and other pyridine containing compounds. NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nitrogen N1 of nicotinamide to produce 1-methylnicotinamide (MNA) and S-adenosylhomocysteine. MNA is a messenger molecule that increases neurite branching, serves as an anti-thrombotic, and has...
Application: Enzyme activity
Purity: >95% estimated by SDS-PAGE
Format: Solution
313.00€
Review
STING (SUMO-tagged, H232 variant, human recombinant)
STING (SUMO-tagged, H232 variant, human...

Item number: Cay15139-50

Stimulator of Interferon Genes (STING) is a component of the innate immune response. STING binds to cyclic dinucleotides, which are bacterial second messengers. Recognition of cyclic-di-GMP (c-di-GMP), c-di-AMP, or c-GMP-AMP leads to activation of NF-kappaB and transcription of immunomodulatory genes, including type I interferon (IFN). Loss of STING regulation contributes to...
Application: Binding assays
Expressed in: E.coli
MW: 34,5 kD
Purity: >95% estimated by SDS-PAGE
Format: Solution
494.00€
Review
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