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Item number: SBB-DE0024-C050
The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is essential for generating a functional virus replication complex. PLpro possesses both deubiquitinating or...
|Keywords:||Papain-like Proteinase, SARS Coronavirus Main Proteinase, Non-structural Protein 3, PL2-PRO, Nsp3|
Item number: 01400.1
Bovine Serum Albumin (BSA), Fraction V is used for various biochemical applications including ELISA (Enzyme-Linked Immunosorbent Assay), high content screenining assays, western blotting, and immunohistochemistry. BSA as a blocking reagent is particularly useful with casein-sensitive antibodies, such as...
From 116.00€ *
Item number: E-PKSR030472.50
GenBank: QHD43415.1. Nsp3 is responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in...
|Keywords:||Non-structural protein 3, nsp3, PL2-PROPapain-like proteinase, PL-PRO, SARS coronavirus main proteinase|
From 243.00€ *
Item number: BM-13001-1000
Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags...
|Keywords:||P1 Proteinase, EC=3.4.-.-|
|Application:||Protein cleavage, Tag removal|
From 175.00€ *
Item number: BPS-100454
Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, Genbank Accession No. NM_004895, a.a. 134-1036(end) with N-terminal FLAG-tag, expressed in a HEK293 expression system. MW = 105 kDa.
|Keywords:||NLRP3, C1orf7, CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin...|
|Expressed in:||human cells|
Item number: BPS-100476
Human NEK7, also known as NIMA Related Kinase 7, GenBank Accession No. NM_133494, a.a. 2-302 (end), with N-terminal His-tag, expressed in a HEK293 cell expression system. MW=37 kDa.
|Keywords:||NEK7, EC=22.214.171.124, NimA-related protein kinase 7, Never in mitosis A-related kinase 7, Serine/threonine-protein kinase Nek7|
|Expressed in:||human cells|
Item number: Cay17926-100
A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around a histone octamer consisting of two copies of each of the core histones, H2A, H2B, H3, and H4. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H3 undergoes many...
|Keywords:||H3FI, H3FB, H3FC, H3FL, H3FK, H3FH, H3FF, H3FD, H3FJ, H3FA, HIST1H3B, HIST1H3H, HIST1H3E, HIST1H3C, HIST1H3I, HIST1H3A,...|
Item number: Cay400076-1
Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis...
|Keywords:||cFBG, FGA, Fibrinopeptide A, Fibrinogen alpha chain, FGB, Fibrinopeptide B, Fibrinogen beta chain, FGG, PRO2061,...|
Item number: Cay60100-5
COX-1 catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: the conversion of arachidonic acid to PGH2. COX-1 is constitutively expressed in almost all animal tissues and is involved in the homeostatic role of eicosanoids. COX-1 from ram seminal vesicles has an...
|Keywords:||COX1, PTGS1, COX-1, PHS 1, PGHS-1, EC=126.96.36.199, PGH synthase 1, Cyclooxygenase-1, Prostaglandin H2 synthase 1,...|
Item number: Cay60122-5
Cyclooxygenase 2 (COX-2) catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins: The conversion fo arachidonic acid (Cay-90010) to PGH2 (Cay-17020). Discoveries of the induction of COX expression by a variety of stimuli such as phorbol esters, lipopolysaccharides, and...
|Keywords:||COX2, PTGS2, COX-2, PHS II, PGHS-2, EC=188.8.131.52, PGH synthase 2, Cyclooxygenase-2, Prostaglandin H2 synthase 2,...|