Products from South Bay Bio

South Bay Bio

South Bay Bio is a biotechnology company dedicated to providing HTS related products with a focus on the ubiquitin proteasome system. The company was formed in the San Francisco Bay area to provide support to local biotechnology companies, and is located in the city of San Jose.

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Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit
Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit

Item number: SBB-KF0120-KI01

South Bay Bio's Cullin4a/Rbx1/DDB1/CRBN Neddylated E3 Ligase TR-FRET Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto the E3 complex in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET...
Keywords: CUL4A, CUL-4A, Cullin-4A
Application: Compound Screening
Reactivity: Human
746.00€ *
Review
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.)...

Item number: SBB-CE0011-C050

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate...
Keywords: Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2
Application: Assays
Reactivity: Human
MW: 118 kD
274.00€ *
Review
UbcH5c [UBE2D3] (human) (rec.) (untagged)
UbcH5c [UBE2D3] (human) (rec.) (untagged)

Item number: SBB-CE0019-C100

UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D3-Ub thioester. UBE2D3 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5c, PUBC, UBC5C, Ubiquitin-protein Ligase D3, p53-regulated Ubiquitin-conjugating Enzyme
Application: Assays
Reactivity: Human
MW: 17 kD
260.00€ *
Review
UbcH7 [UBE2L3] (human) (rec.) (untagged)
UbcH7 [UBE2L3] (human) (rec.) (untagged)

Item number: SBB-CE0020-C100

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules...
Keywords: Ubiquitin-conjugating Enzyme E2 L3, E2-F1, L-UBC, UBCE7, UbcM4, UBE2L3, Ubiquitin-protein Ligase L3
Application: Assays
Reactivity: Human
MW: 18 kD
260.00€ *
Review
UbcH5a [UBE2D1] (human) (rec.) (untagged)
UbcH5a [UBE2D1] (human) (rec.) (untagged)

Item number: SBB-CE0021-C100

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5a, PUBC1, UBC5A, Ubiquitin-protein Ligase D1, p53-regulated Ubiquitin-conjugating Enzyme 1
Application: Assays
Reactivity: Human
MW: 17 kD
260.00€ *
Review
UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)
UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)

Item number: SBB-CE0022-C100

UBE2K (UbcH1) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2K via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2K-Ub thioester. UBE2K is capable of...
Keywords: Ubiquitin-conjugating Enzyme E2, E2-25K, Hip2, HYPG, LIG, UBE2K, UBE2K-25K, Huntingtin-interacting Protein 2
Application: Assays
Reactivity: Human
MW: 22 kD
260.00€ *
Review
UbcH5b [UBE2D2] (human) (rec.) (untagged)
UbcH5b [UBE2D2] (human) (rec.) (untagged)

Item number: SBB-CE0027-C100

UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5b, PUBC1, UBC5B, Ubiquitin-protein Ligase D2, p53-regulated Ubiquitin-conjugating Enzyme 1
Application: Assays
Reactivity: Human
MW: 17 kD
224.00€ *
Review
UcH-L3 (human) (rec.) (untagged)
UcH-L3 (human) (rec.) (untagged)

Item number: SBB-DE0023-C050

UCHL3 (Ubiquitin C-terminal Hydrolase L3) is a deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8....
Keywords: Ubiquitin C-terminal Hydrolase L3, Ubiquitin Thioesterase L3
Application: Assays
Reactivity: Human
MW: 26 kD
162.00€ *
Review
PLpro (SARS Coronavirus) (rec.) (His)
PLpro (SARS Coronavirus) (rec.) (His)

Item number: SBB-DE0024-C050

The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is essential for generating a functional virus replication complex. PLpro possesses both deubiquitinating or...
Keywords: Papain-like Proteinase, SARS Coronavirus Main Proteinase, Non-structural Protein 3, PL2-PRO, Nsp3
Application: Assays
Reactivity: Sars-cov
MW: 37 kD
217.00€ *
Review
NEDP1 [SENP8] (human) (rec.) (His)
NEDP1 [SENP8] (human) (rec.) (His)

Item number: SBB-DE0025-C050

NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate...
Keywords: NEDD8-specific Protease 1, Sentrin-specific Protease 8, Deneddylase-1, Sentrin/SUMO-specific Protease SENP8, DEN1, PRSC2
Application: Assays
Reactivity: Human
MW: 27 kD
162.00€ *
Review
SENP1 (catalytic domain) (human) (rec.) (His)
SENP1 (catalytic domain) (human) (rec.) (His)

Item number: SBB-DE0026-C050

SUMO/Sentrin Specific Peptidase 1 (SENP1) is a member of the SENP family of proteases, which belong to the group of cysteine-­type peptidases. SENP1 is a SUMO-specific enzyme that catalyzes two essential functions. Processing the full-length versions of SUMO1, SUMO2 and SUMO3 into its mature forms and the...
Keywords: Sentrin-specific Protease 1, Sentrin/SUMO-specific Protease SENP1
Application: Assays
Reactivity: Human
MW: 32 kD
162.00€ *
Review
Mdm2 E3 Ligase TR-FRET Kit
Mdm2 E3 Ligase TR-FRET Kit

Item number: SBB-KF0030-KI01

South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Keywords: MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase...
Application: Enzyme assays
Reactivity: Human
746.00€ *
Review
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