• Please note that we do not deliver goods between 19.12.2019 and 03.01.2020 due to public holidays. However, we are happy to accept orders for deliveries in 2020 during this period.

Products from South Bay Bio

South Bay Bio

South Bay Bio is a biotechnology company dedicated to providing HTS related products with a focus on the ubiquitin proteasome system. The company was formed in the San Francisco Bay area to provide support to local biotechnology companies, and is located in the city of San Jose.

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20S Proteasome (human) (untagged)
20S Proteasome (human) (untagged)

Item number: SBB-PP0005-C050

The ubiquitin-proteasome pathway is the major proteolytic system in eukaryotic cells, where it catalyzes the selective degradation of short-lived regulatory proteins or the rapid turnover of misfolded proteins. One of the most important proteases in this pathway is the 26S proteasome, an ATP-dependent proteolytic...
Application: Assays
Reactivity: Human
MW: 700 kD
174.00€ *
Review
Ubiquitin aldehyde (human) (rec.)
Ubiquitin aldehyde (human) (rec.)

Item number: SBB-PS0031-C050

Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic organisms. The addition of ubiquitin to a substrate protein is called ubiquitination or ubiquitylation. Ubiquitination can affect proteins in many ways: it can signal for their degradation via the proteasome,...
Application: Assays
Reactivity: Human
MW: 9 kD
119.00€ *
Review
Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit
Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit

Item number: SBB-KF0120-KI01

South Bay Bio's Cullin4a/Rbx1/DDB1/CRBN Neddylated E3 Ligase TR-FRET Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto the E3 complex in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET...
Keywords: CUL4A, CUL-4A, Cullin-4A
Application: Compound Screening
Reactivity: Human
746.00€ *
Review
20S Constitutive Proteasome Assay Kit
20S Constitutive Proteasome Assay Kit

Item number: SBB-KP0038-KI01

South Bay Bio's kit is designed to test for specific activity of 20S proteasome. The kit provides purified 20S proteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), Caspase-like activity of the proteasome subunits beta1/PSMB6 (LLE-AMC) and Chymotrypsin-like activity of beta5/PSMB5...
Application: Compound Screening
428.00€ *
Review
ITCH E3 Ligase TR-FRET Kit
ITCH E3 Ligase TR-FRET Kit

Item number: SBB-KF0035-KI01

South Bay Bio's ITCH TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto ITCH in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Keywords: Itch, ITCH, AIP4, NAPP1, EC=2.3.2.26, NFE2-associated polypeptide 1, Atrophin-1-interacting protein 4, E3...
Application: Enzyme assays
Reactivity: Human
746.00€ *
Review
Ubiquitin (human) (rec.) (Cy5)
Ubiquitin (human) (rec.) (Cy5)

Item number: SBB-TR0015-C050

Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
Keywords: UBB, Ubiquitin B
Application: Assays
Reactivity: Human
MW: 9 kD
201.00€ *
Review
Ubiquitin (human) (rec.) (untagged)
Ubiquitin (human) (rec.) (untagged)

Item number: SBB-UP0013-M010

Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of...
Keywords: UBB, Ubiquitin B
Application: Assays
Reactivity: Human
MW: 9 kD
86.00€ *
Review
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.)...

Item number: SBB-CE0011-C050

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate...
Keywords: Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2
Application: Assays
Reactivity: Human
MW: 118 kD
274.00€ *
Review
UbcH5c [UBE2D3] (human) (rec.) (untagged)
UbcH5c [UBE2D3] (human) (rec.) (untagged)

Item number: SBB-CE0019-C100

UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D3-Ub thioester. UBE2D3 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5c, PUBC, UBC5C, Ubiquitin-protein Ligase D3, p53-regulated Ubiquitin-conjugating Enzyme
Application: Assays
Reactivity: Human
MW: 17 kD
260.00€ *
Review
UbcH7 [UBE2L3] (human) (rec.) (untagged)
UbcH7 [UBE2L3] (human) (rec.) (untagged)

Item number: SBB-CE0020-C100

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules...
Keywords: Ubiquitin-conjugating Enzyme E2 L3, E2-F1, L-UBC, UBCE7, UbcM4, UBE2L3, Ubiquitin-protein Ligase L3
Application: Assays
Reactivity: Human
MW: 18 kD
260.00€ *
Review
UbcH5a [UBE2D1] (human) (rec.) (untagged)
UbcH5a [UBE2D1] (human) (rec.) (untagged)

Item number: SBB-CE0021-C100

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of...
Keywords: Ubiquitin-conjugating Enzyme H5a, PUBC1, UBC5A, Ubiquitin-protein Ligase D1, p53-regulated Ubiquitin-conjugating Enzyme 1
Application: Assays
Reactivity: Human
MW: 17 kD
260.00€ *
Review
Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]
Ac-Pro-Ala-Leu-AMC [Ac-PAL-AMC]

Item number: SBB-PS0007-M002

Lyophilized powder. Soluble in DMSO. Ac-PAL-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the immunoproteasome. Hydrolysis of this substrate by the beta1i-subunit of the immunoproteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm....
Keywords: Proteasome Substrate
Application: Fluorogenic peptide substrate
MW: 498,6 D
158.00€ *
Review
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