Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
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Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
From 332.00€ *
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Item number: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Keywords: Plant Sterol Mixture, (qualitative)
Application: Sterols - Plant Sterols and Steryl Glucosides
176.00€ *
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Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
From 35.00€ *
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Item number: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Keywords: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Application: Standard
MW: 383.6 D
From 65.00€ *
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Serotonin (hydrochloride)
Serotonin (hydrochloride)

Item number: Cay14332-50

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Keywords: 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
Application: Monoamine neurotransmitter
CAS 153-98-0
MW: 212.7 D
From 37.00€ *
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Indomethacin
Indomethacin

Item number: Cay70270-1000

Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in...
Keywords: Indocin, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
Application: COX inhibitor
CAS 53-86-1
MW: 357.8 D
25.00€ *
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alpha-Linolenic Acid
alpha-Linolenic Acid

Item number: Cay90210-50

alpha-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.
Keywords: ALA, 9Z,12Z,15Z-octadecatrienoic acid
Application: Bioactive lipid studies
CAS 463-40-1
MW: 278.4 D
From 25.00€ *
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Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re)...

Item number: IAX-100-003-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Keywords: Monophosphoryl Lipid A [MPLA] derived from E. coli R515 (Re) LPS (biosynthetic)
Application: TLR4 activator
From 125.00€ *
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Ganglioside GM3 . sodium salt (bovine brain)
Ganglioside GM3 . sodium salt (bovine brain)

Item number: AG-CN2-9002-M001

Semisynthetic. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions,...
Keywords: GM3 . Na, Monosialoganglioside GM3 . Na
Application: Acidic glycosphingolipid
CAS 54827-14-4
MW: 1180,5 D
231.00€ *
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Ganglioside GD1b . disodium salt (bovine brain)
Ganglioside GD1b . disodium salt (bovine brain)

Item number: AG-CN2-9004-M001

Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
Keywords: GD1b . 2Na, Disialoganglioside GD1b . 2Na
Application: Acidic glycosphingolipid
CAS 19553-76-5
MW: 1836,1 D
160.00€ *
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Ganglioside GD3 . disodium salt (bovine brain)
Ganglioside GD3 . disodium salt (bovine brain)

Item number: AG-CN2-9005-M001

Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
Keywords: GD3 . 2Na, Disialoganglioside GD3 . 2Na
Application: Acidic glycosphingolipid
CAS 62010-37-1
MW: 1470,8 D
From 193.00€ *
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alpha-Galactosylceramide Analog I (water soluble) [KBC-007]
alpha-Galactosylceramide Analog I (water soluble) [KBC-007]

Item number: AG-CR1-3608-C100

Colorless oil. Soluble in DMSO (~20mg/ml), ethanol (~12mg/ml) or water (~18mg/ml). Synthetic, soluble analog of alpha-galactosylceramide (Prod. No. AG-CN2-0013), Immunostimulant, Potent stimulator of natural killer T (NKT) cells, Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse...
Keywords: alpha-Gal-Cer Water Soluble Analog, alpha-Galactosylceramide Analog I, alpha-Gal-Cer Analog I
Application: Immunostimulant, CD1d ligand
CAS 1037297-61-2
MW: 817,2 D
121.00€ *
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