Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
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Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

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all-cis-7,10,13,16,19-Docosapentaenoic Acid methyl ester
all-cis-7,10,13,16,19-Docosapentaenoic Acid methyl ester

Item number: Cay9001870-5

Docosapentaenoic acid (DPA, Cay-90165) is an omega-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and increases on dietary supplementation. DPA methyl ester is a more lipid-soluble form of DPA. omega-3 and omega-6 fatty acids...
Keywords: all-cis-7,10,13,16,19-DPA methyl ester, all-Z-7,10,13,16,19-DPA methyl ester, DPA methyl ester,...
Application: Omega-3 fatty acid ester, GC
CAS 108698-02-8
MW: 344.5 D
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Eicosapentaenoic Acid
Eicosapentaenoic Acid

Item number: Cay90110-50

EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some...
Keywords: EPA, Timnodonic Acid, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid
Application: Bioactive lipid assays
CAS 10417-94-4
MW: 302.5 D
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Palmitic Acid
Palmitic Acid

Item number: Cay10006627-10

Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids...
Keywords: hexadecanoic acid
Application: Bioactive lipid assays
CAS 57-10-3
MW: 256.4 D
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Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
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Prostaglandin D2
Prostaglandin D2

Item number: Cay12010-1

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Keywords: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
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U-46619
U-46619

Item number: Cay16450-1

U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist. It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0,...
Keywords: 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha, 9,11-dideoxy-9alpha,11alpha-methanoepoxy Prostaglandin F2alpha,...
Application: TP receptor agonist
CAS 56985-40-1
MW: 350.5 D
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tetranor-PGEM-d6
tetranor-PGEM-d6

Item number: Cay314840-25

Tetranor prostaglandin E metabolite-d6 (tetranor-PGEM-d6) contains six deuterium atoms at the 13, 13, 14, 14, 15, and 15 positions. It is intended for use as an internal standard for the quantification of tetranor PGEM by GC- or LC-mass spectrometry. Tetranor PGEM-d6 is the major urinary metabolite of PGE1 and PGE2....
Keywords: tetranor-Prostaglandin E Metabolite-d6,...
Application: Standard
CAS 1240398-16-6
MW: 334.4 D
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(±)11-HETE
(±)11-HETE

Item number: Cay34500-25

(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid (Cay-90010). The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.
Keywords: (±)11-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 73804-65-6
MW: 320.5 D
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2-Arachidonoyl Glycerol
2-Arachidonoyl Glycerol

Item number: Cay62160-25

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
Keywords: 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester
Application: CB1 receptor agonist
CAS 53847-30-6
MW: 378.6 D
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11(S)-HETE
11(S)-HETE

Item number: Cay34510-25

The synthesis of 11-HETE by rat PMNL has been reported, but the stereochemistry of the 11-HETE produced is not defined. There are no definitive reports of a mammalian 11(S)-LO. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
Keywords: 11S-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 54886-50-9
MW: 320.5 D
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Item number: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Keywords: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Application: Standard
MW: 383.6 D
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Oleic Acid
Oleic Acid

Item number: Cay90260-500

Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue. It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic...
Keywords: cis-9-Octadecenoic acid, 9Z-Octadecenoic acid
Application: Bioactive lipid assays
CAS 112-80-1
MW: 282.5 D
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