Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
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Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

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Arachidonic Acid-d11
Arachidonic Acid-d11

Item number: Cay10006758-100

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
Keywords: AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Application: GC-MS, LC-MS, Internal standard
MW: 315.5 D
From 48.00€ *
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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Item number: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Keywords: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158.00€ *
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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Item number: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Keywords: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132.00€ *
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Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
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6-keto Prostaglandin F1alpha-d4
6-keto Prostaglandin F1alpha-d4

Item number: Cay315210-25

6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
Keywords: 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Application: Standard
CAS 82414-64-0
MW: 374.5 D
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Item number: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Keywords: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Application: Standard
MW: 383.6 D
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Item number: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Keywords: Plant Sterol Mixture, (qualitative)
Application: Sterols - Plant Sterols and Steryl Glucosides
176.00€ *
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Serotonin (hydrochloride)
Serotonin (hydrochloride)

Item number: Cay14332-50

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Keywords: 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
Application: Monoamine neurotransmitter
CAS 153-98-0
MW: 212.7 D
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Indomethacin
Indomethacin

Item number: Cay70270-1000

Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in...
Keywords: Indocin, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
Application: COX inhibitor
CAS 53-86-1
MW: 357.8 D
25.00€ *
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alpha-Linolenic Acid
alpha-Linolenic Acid

Item number: Cay90210-100

alpha-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.
Keywords: ALA, 9Z,12Z,15Z-octadecatrienoic acid
Application: Bioactive lipid studies
CAS 463-40-1
MW: 278.4 D
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Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re)...

Item number: IAX-100-003-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Keywords: Monophosphoryl Lipid A [MPLA] derived from E. coli R515 (Re) LPS (biosynthetic)
Application: TLR4 activator
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