Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
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Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

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Arachidonic Acid-d11
Arachidonic Acid-d11

Item number: Cay10006758-100

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
Keywords: AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Application: GC-MS, LC-MS, Internal standard
MW: 315.5 D
From 48.00€ *
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Palmitoyl Ethanolamide
Palmitoyl Ethanolamide

Item number: Cay90350-5

Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro. PEA is an endocannabinoid which has been shown to significantly elevate cAMP in cells...
Keywords: Palmidrol, PEA, N-(2-hydroxyethyl)-hexadecanamide
Application: Bioactive lipid assays
CAS 544-31-0
MW: 299.5 D
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Leukotriene B4
Leukotriene B4

Item number: Cay20110-25

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
Keywords: LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 71160-24-2
MW: 336.5 D
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Sphingosine-1-phosphate
Sphingosine-1-phosphate

Item number: Cay62570-1

Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin, it exhibits a wide range of biological activities. Not only does it enhance cell growth, but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of...
Keywords: S1P, Sphingosine-1-Phosphoric Acid, 2S-amino-4E-octadecene-1,3R-diol 1-(dihydrogen phosphate)
Application: Bioactive lipid assays
CAS 26993-30-6
MW: 379.5 D
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Stearoyl Ethanolamide
Stearoyl Ethanolamide

Item number: Cay90245-5

Stearoyl ethanolamide is a member of the family of fatty N-acyl ethanolamines collectively called anandamides. Stearoyl ethanolamide is the most abundant of several fatty acid ethanolamides produced by the PLD hydrolysis of mouse neuroblastoma cell membrane phospholipids. The specific role of stearoyl ethanolamide...
Keywords: Ceramid, Stearic Acid Ethanolamide, N-(2-hydroxyethyl)-octadecanamide
Application: Bioactive lipid assays
CAS 111-57-9
MW: 327.6 D
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Palmitoyl Ethanolamide-d4
Palmitoyl Ethanolamide-d4

Item number: Cay10007824-100

Palmitoyl ethanolamide-d4 (PEA-d4) contains four deuterium atoms at the 7, 7', 8, and 8' positions. It is intended for use as an internal standard for the quantification of PEA by GC- or LC-mass spectrometry. PEA is an endogenous cannabinoid found in brain, liver, and other mammalian tissues. PEA has also been...
Keywords: Palmidrol-d4, PEA-7,7,8,8-d4, N-(2-hydroxyethyl)-hexadecanamide-7,7,8,8-d4
Application: Standard
CAS 1159908-45-8
MW: 303.5 D
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Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
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L-161,982
L-161,982

Item number: Cay10011565-1

Prostaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4). L-161,982 is a potent and selective EP4 receptor antagonist. It demonstrates selective binding to human EP4 receptors with a Ki value of 0.024 µM compared to other receptors of the prostanoid family, EP1, EP2, EP3,...
Keywords: N-[[4'-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1'-biphenyl]-2-yl]sulfony...
Application: EP4 receptor antagonist
CAS 147776-06-5
MW: 654.7 D
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U-46619
U-46619

Item number: Cay16450-1

U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist. It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0,...
Keywords: 9,11-dideoxy-9alpha,11alpha-methanoepoxy PGF2alpha, 9,11-dideoxy-9alpha,11alpha-methanoepoxy Prostaglandin F2alpha,...
Application: TP receptor agonist
CAS 56985-40-1
MW: 350.5 D
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Item number: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Keywords: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Application: Standard
MW: 383.6 D
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2-Arachidonoyl Glycerol
2-Arachidonoyl Glycerol

Item number: Cay62160-1

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
Keywords: 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester
Application: CB1 receptor agonist
CAS 53847-30-6
MW: 378.6 D
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Arachidonoyl Ethanolamide
Arachidonoyl Ethanolamide

Item number: Cay90050-5

Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid, originally isolated from porcine brain. AEA is an endogenous cannabinoid neurotransmitter that binds to both cannabinoid 1 (CB1) and CB2 receptors. AEA has Ki values ranging from 61 to 543 nM for CB1 receptors and from 279 to 1,940 nM for...
Keywords: AEA, Anandamide, N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Application: Bioactive Lipid assays
CAS 94421-68-8
MW: 347.5 D
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