Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the... read more »
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Lipids

Lipids are organic small molecules, that are usually hydrophobic or amphiphillic. This group includes fat, fatty acids, waxes, triglycerides, sterols and phospholipids for example. Lipids are the main structural component of biological membranes of all cells. As such bacterial lipid structures and glycolipids can serve as pathogen-associated-molecular-patterns (PAMPs) and are recognized by our immune system. Various lipids of bacterial origin are therefore used as immunostimulants.

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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Item number: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Keywords: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Item number: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Keywords: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Item number: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Keywords: Plant Sterol Mixture, (qualitative)
Application: Sterols - Plant Sterols and Steryl Glucosides
176.00€ *
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Fumonisin B1
Fumonisin B1

Item number: Cay62580-1

Fumonisin B1 is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)....
Keywords: FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,...
Application: Ceramide synthase inhibitor
CAS 116355-83-0
MW: 721.8 D
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Arachidonic Acid (peroxide free)
Arachidonic Acid (peroxide free)

Item number: Cay90010.1-50

Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Arachidonic acid oxidizes spontaneously on exposure to room air, yielding a complex mixture of fatty acid peroxides Peroxide-free arachidonic acid is obtained after removal of the peroxides by silicic acid...
Keywords: 5Z,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 506-32-1
MW: 304.5 D
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Prostaglandin A1
Prostaglandin A1

Item number: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Keywords: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
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Prostaglandin E2
Prostaglandin E2

Item number: Cay14010-5

PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Item number: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Keywords: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Application: Standard
MW: 383.6 D
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Prostaglandin J2
Prostaglandin J2

Item number: Cay18500-500

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor...
Keywords: PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 60203-57-8
MW: 334.5 D
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Serotonin (hydrochloride)
Serotonin (hydrochloride)

Item number: Cay14332-50

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Keywords: 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
Application: Monoamine neurotransmitter
CAS 153-98-0
MW: 212.7 D
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Indomethacin
Indomethacin

Item number: Cay70270-1000

Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in...
Keywords: Indocin, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
Application: COX inhibitor
CAS 53-86-1
MW: 357.8 D
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