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Item number: ANC-181-520
Human CD32 exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses.
|Keywords:||Anti-CD32, Anti-CDw32, Anti-FCGR2A, Anti-FcRII-a, Anti-Fc-gamma-RIIa, Anti-FCGR2B, Anti-FcRII-b, Anti-Fc-gamma-RIIb,...|
Item number: ANC-216-520
Human CD64 is a high affinity receptor for monomeric human IgG1 and IgG3 which is expressed on macrophages, monocytes and gamma-interferon induced neutrophils. CD64 plays an important role in clearance of immune complexes and in antibody dependent cytoxicity.
|Keywords:||Anti-FcRI, Anti-CD64, Anti-FCG1, Anti-FCGR1A, Anti-FcgammaRIa, Anti-Fc-gamma RI, Anti-Fc-gamma RIA, Anti-IgG Fc receptor...|
|Reactivity:||Human, Dog, Monkey|
Item number: ANC-165-520
Human CD16 is a low affinity receptor for complexed IgG and occurs in two distinct forms, as a glycosyl phosphatidyl inositol (GPI) anchored protein in granulocytes and as an integral membrane protein on NK cells and macrophages.
|Keywords:||Anti-CD16b, Anti-CD16B, Anti-FCGR3B, Anti-CD16a, Anti-CD16A, Anti-FCGR3A, Anti-Fc-gamma RIII|
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Item number: 800-102-098
Item number: ANC-167-520
Human CD18 (beta integrin) forms a heterodimer with either alphaL, alphaM, or alphaX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses.
|Keywords:||Anti-CD18, Anti-ITGB2, Anti-Integrin beta-2, Anti-Complement receptor C3 subunit beta, Anti-Cell surface adhesion...|
|Reactivity:||Human, Monkey, Rabbit|
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Item number: 700-102-098
Item number: ANC-144-520
The human CD3/T cell receptor (TcR) complex is made up of the CD3 proteins (gamma, delta, 2 epsilon) and teh zeta-chain in association with either alpha/beta or gamma/delta proteins of the TcR. The TcR recognizes antigens in association with MHC molecules after which protein chains of the CD3 complex mediate...
|Keywords:||Anti-T3E, Anti-CD3E, Anti-CD3e, Anti-T-cell surface glycoprotein CD3 epsilon chain, Anti-T-cell surface antigen T3/Leu-4...|
|Application:||FC, WB, FA|
Item number: ANC-177-520
Human CD28 is an important costimulatory molecule found on all CD4 T cells and on about half of the CD8 T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA and activation of CD8 cytotoxic T lymphocytes. The ligands for...
|Keywords:||Anti-TP44, Anti-CD28, Anti-T-cell-specific surface glycoprotein CD28|
Item number: ANC-359-520
Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation.
|Keywords:||Anti-CD152, Anti-CTLA4, Anti-CTLA-4, Anti-Cytotoxic T-lymphocyte protein 4, Anti-Cytotoxic T-lymphocyte-associated antigen 4|
|Reactivity:||Human, Pig, Cow, Cat, Dog|