Cytokines

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF),... read more »
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Cytokines

In this category you will find extracellular regulatory proteins and peptides such as interferons (IFN), interleukins (IL), colony stimulating factors (CSF), tumor necrosis factors (TNF), chemokines, and growth factors for your research applications. Cytokines regulate the differentiation, proliferation, and activity of cells. For this reason they are often used in cell culture experiments. Cytokine products are also used as controls in immunoassays. Information, such as the specific activity of a cytokine, the amino acid sequence, results of a monocyte activation tests, and more can be found in the datasheet of each product.

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Fibroblast Growth Factor basic, human recombinant (rHuFGF-basic)
Fibroblast Growth Factor basic, human recombinant...

Item number: 50361.50

The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated, polypeptide chain containing 154...
Keywords: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b
Application: Cell culture
Expressed in: E.coli
Origin: Human
MW: 17.2 kD
1.00€ * From 0.80€ *
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Interleukin-1 beta, human recombinant (rHuIL-1-beta)
Interleukin-1 beta, human recombinant (rHuIL-1-beta)

Item number: 94886.10

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release...
Keywords: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear...
Application: Cell biology studies
Expressed in: E.coli
Origin: Human
MW: 17.0 kD
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Erythropoietin alpha, human recombinant (rHuEPO-a)
Erythropoietin alpha, human recombinant (rHuEPO-a)

Item number: 64351.1

Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. (www.uniprot.org) Produced in CHO cells. Single polypeptide chain containing 165 amino acids. Predicted molecular mass of 21,000 Dalton and...
Keywords: Erythropoietin-Alpha, EPO-a, EPO-alpha, Epoetin, EP, MGC138142
Expressed in: Hamster cells
Origin: Human
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Tumor Necrosis Factor alpha (TNF alpha), human recombinant (HumaXpress)
Tumor Necrosis Factor alpha (TNF alpha), human...

Item number: HZ-1014

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin <0.1 EU/µg.
Keywords: HZ-10141000ug (rHuTNFa) (rHuTNF-a), Tumor necrosis factor, TNFA, TNFSF2, Cachectin, TNF-alpha
Application: Cell culture, Bioassays
Expressed in: Human cells
Origin: Human
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Interleukin-6 (IL-6), human recombinant (HumaXpress)
Interleukin-6 (IL-6), human recombinant (HumaXpress)

Item number: HZ-1019

Authentic recombinant human protein, human cell expressed, which in general ensures proper folding, phosphorylation, disulfide bridge formation, proteolytic processing, and glycosylation. Endotoxin <0.5 EU/µg.
Keywords: HZ-1019100ug (rHuIL-6), IL6, IFNB2, IFN-beta-2
Application: Cell culture, Bioassays
Expressed in: Human cells
Origin: Human
From 205.00€ *
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CCL2 (MCP-1), swine recombinant (rpoCCL2)
CCL2 (MCP-1), swine recombinant (rpoCCL2)

Item number: RP0017S-025

Biologically active. Produced in Yeast. Amino acid sequence: QPDAINSPVT CCYTLTSKKI SMQRLMSYRR VTSSKCPKEA VIFKTIAGKE ICAEPKQKWV QDSISHLDKK NQTPKP. Protein function: Chemotactic factor that attracts monocytes, but not neutrophils. [The UniProt Consortium]
Keywords: CCL2, MCP-1, SCYA2, C-C motif chemokine 2, Small-inducible cytokine A2, Monocyte chemotactic protein 1, Monocyte...
Application: Cell culture
Expressed in: Yeast
Origin: Swine
MW: 8,6 kD
324.00€ *
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Sonic HedgeHog, human recombinant (rHuSHH)
Sonic HedgeHog, human recombinant (rHuSHH)

Item number: 97290.25

Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of...
Keywords: SHH, HHG-1, HHG1, Sonic hedgehog protein, TPT, HLP3, HPE3, SMMCI, TPTPS, MCOPCB5
Application: Cell culture
Expressed in: E.coli
Origin: Human
MW: 19683 D
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Vascular Endothelial Growth Factor-165, human recombinant (rHuVEGF-165-HEK)
Vascular Endothelial Growth Factor-165, human recombinant...

Item number: 97324.10

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds...
Keywords: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609
Application: Cell Culture
Expressed in: Human cells
Origin: Human
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Interleukin-10, HEK, human recombinant (rHuIL-10-HEK)
Interleukin-10, HEK, human recombinant (rHuIL-10-HEK)

Item number: 97490.10

Human recombinant Interleukin-10 produced in HEK cells is a glycosylated non-disulfide bonded homodimer, having a total molecular weight of 17kDa. IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It...
Keywords: B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.
Application: Cell Culture
Expressed in: Human cells
Origin: Human
MW: 17000 D
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Flt3-Ligand, mouse recombinant (rmFlt3)
Flt3-Ligand, mouse recombinant (rmFlt3)

Item number: 87327.10

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. (www.uniprot.org) Produced in E.coli. Non-glycosylated, polypeptide chain containing 144 amino acids. The activity is determined by the ability to generate...
Keywords: Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3
Application: Cell Culture
Expressed in: E.coli
Origin: Mouse
MW: 16431.00 D
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Interleukin-6, human recombinant (rHuIL-6)
Interleukin-6, human recombinant (rHuIL-6)

Item number: 50436.20

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells...
Keywords: IFN-b2, B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2, Interferon beta-2,...
Application: Cell culture
Expressed in: E.coli
Origin: Human
MW: 21 kD
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Interleukin-12 p40, His Tag, Baculovirus, human recombinant (rHuIL-12-p40-Baculovirus-His)
Interleukin-12 p40, His Tag, Baculovirus, human...

Item number: 97492.10

Human recombinant IL-12 p40 produced in Hi-5 cell using Baculovirus is a single polypeptide chain containing 315 amino acids (23-328) and having a molecular mass of 29.4kDa. Active IL-12 is a p70 disulphide-linked dimer composed of p35 and p40 subunits. The protein is a pleiotropic cytokine produced primarily by...
Keywords: NKSF2, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), TSF,...
Application: Bioassay
Expressed in: Insect cells
Origin: Human
MW: 35800 D
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