With so many possibilities, it can be difficult and tedious to select the appropriate calcium indicator for a given calcium ion flux assay. To streamline the process, here is what we consider to be the eight best single-wavelength, green fluorescent calcium indicators available.
Fluorescent indicators that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers.
The Cannabis sativa plant has seen a tremendous amount of notoriety over the last few years due to an increasing support of legalization.
iGEM (or international Genetically Engineered Machine) is a non-profit, student competition for synthetic biology. Every year, the competition inspires thousands of students to work together in teams and push the boundaries of synthetic biology by tackling everyday issues facing the world.
Choosing the right ELISA blocking buffer often comes down to fully understanding the factors that determine ELISA plate blocking – especially the stabilizing processes involved.
Just eight years ago a previously unknown form of controlled cell death with significant similarities to oxytosis was discovered.
The B cell-stimulating molecules BAFF and APRIL are critical factors in the maintenance of the B cell pool and humoral immunity.
Because at times it can seem overwhelming to identify the most suitable inhibitor from the plethora of molecules available for use, we gathered a list of parameters that should be considered during the selection process.
AAT Bioquest offers a variety of dark-FRET peptide substrates and fluorogenic substrates which can be effectively used to screen for inhibitors of coronavirus proteases, papain-like proteases and more.
Progranulin is a stress-induced protein with multifunctional biological activities, including major roles in cancer, inflammation, metabolic diseases and neurodegeneration.
HMGB1 has attracted the attention of both basic and clinical researchers as it is associated with various pathologies such as cancer, sepsis, arteriosclerosis, chronic rheumatoid arthritis, and nephritis.
Kinases are arguably one of the most important drug targets due to the roles their mutations, overexpression, and dysregulation play in all major pathologies, including immunological, inflammatory, degenerative, metabolic, cardiovascular, and infectious diseases.
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