Products from BPS

BPS

BPS Bioscience Inc., headquartered in the heart of one of the world's largest clusters of life science research institutes and companies, San Diego, California,, is the leading provider of highest quality HDACs, histone demethylases and methyltransferases, ubiquitin pathway proteins, phosphodiesterases, kinases, phosphatases, and other recombinant enzymes. BPS also provides custom protein expression, biochemical and cell-based assays, and compound screening services to accelerate your drug discovery research.

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Anti-GST-like protein, clone 1C7
Anti-GST-like protein, clone 1C7

Item number: BPS-25014

Recognizes GST-like protein from insect Sf9 cells (Spodoptera frugiperda). No cross-reaction with GST tag from S. japonicum or GST fusion proteins. Immunogen: Full length S. frugiperda GST-like protein, purified from Sf9 cells. Applications: IP, Removal of contaminating GST-like protein from insect expressed...
Application: IP
329.00€
Review
Anti-5 hmC  (rabbit)
Anti-5 hmC (rabbit)

Item number: BPS-25204

5 hydroxymethylcytosine (5 hmC) results from the enzymatic conversion of 5 methylcytosine into 5 hydroxymethylcytosine by the TET family of iron dependent oxygenases. 5 hmC bases were recently discovered in mammalian DNA, in Purkinje neurons, in granule cells and embryonic stem cells where theyare present at high...
Keywords: Anti-5 hydroxymethylcytosine, Anti-5-hydroxymethyl-cytosine
Application: HMeDIP, ELISA, Dot Blot
389.00€
Review
Anti-5 mC, clone 33D3
Anti-5 mC, clone 33D3

Item number: BPS-25206

The 5 methylcytosine antibody (clone 33D3) is the most published and widely used antibody for DNA methylation analysis. It has been validated for Methylated DNA Immunoprecipitation (MeDIP seq, MeDIP on chip), Immunofluorescence, Flow Cytometry, Dot blot & ELISA.
Keywords: Anti-5 hydroxymethylcytosine, Anti-5-hydroxymethyl-cytosine
Application: MeDIP, ELISA, Dot Blot, IF, FISH, Southern blot
389.00€
Review
DNA Polymerase Beta (POLB), human recombinant protein, N-terminal His-tag
DNA Polymerase Beta (POLB), human recombinant...

Item number: BPS-21000-2

Human DNA polymerase beta, also known as Pol beta and POLB (GenBank Accession No. NM_002690), amino-acids 2-335 (end), with N-terminal His-tag, MW=39 kDa, expressed in an E. coli cell expression system.
Keywords: POLB, EC=2.7.7.7, EC=4.2.99.-, DNA polymerase beta
Application: DNA synthesis, DNA repair, As an antigen for Western blotting, For inhibitor screening
Reactivity: Human
MW: 39 kD
From 443.00€
Review
BAM7
BAM7

Item number: BPS-27607-2

BAM7 is a direct and selective activator of BAX with IC50 value of 3.3 µM.
Keywords: BAM 7, BAM-7, (4E)-4-[(2-ethoxyphenyl)hydrazinylidene]-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazol-3-one
Application: Bax inhibitor
MW: 405.5 D
From 344.00€
Review
CDK6, His-Tag
CDK6, His-Tag

Item number: BPS-100031

Human CDK6, also known as Cell division protein kinase 6, MCPH12, and PLSTIRE GenBank Accession No. NM_001259, a.a. 2-end, expressed in a Baculovirus infected Sf9 expression system. MW = 38 kDa.
Keywords: CDK6, CDKN6, EC=2.7.11.22, Cyclin-dependent kinase 6, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE
Application: Kinase
Reactivity: Human
MW: 38 kD
450.00€
Review
CTLA4 (Woodchuck), Fc-Fusion (Human), Avi-tag HiP(TM)
CTLA4 (Woodchuck), Fc-Fusion (Human), Avi-tag...

Item number: BPS-100037

Woodchuck secreted CTLA4, also known as Cytotoxic T-lymphocyte-associated protein 4 and CD152, with N-terminal Avi-TagTM fused to the Fc region of Human IgG1, a.a. 36-162 expressed in a HEK293 cell expression system. MW = 42 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Keywords: Cytotoxic T-lymphocyte associated antigen 4
Application: Immunotherapy studies
Reactivity: Woodchuck
MW: 42+ kD
405.00€
Review
B7-1 (Woodchuck), Fc-fusion (Human), Avi-Tag, Biotin-labeled
B7-1 (Woodchuck), Fc-fusion (Human), Avi-Tag,...

Item number: BPS-100040

Woodchuck B7-1, also known as CD80, with C-terminal Avi-Tag fused to the Fc-region of Human IgG1. a.a 30-237, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag(TM) technology. MW = 52 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Keywords: CD80 molecule
Application: Immunotherapy studies
Reactivity: Woodchuck
MW: 52+ kD
551.00€
Review
BTLA, Fc Fusion, Avi-Tag, Biotin-Labeled
BTLA, Fc Fusion, Avi-Tag, Biotin-Labeled

Item number: BPS-100047

Human B- and T-lymphocyte attenuator BTLA, also known as CD272, GenBank Accession No. NM_181780, a.a. 31-150, with C-terminal Avi-Tag fused to the Fc region of Human IgG1, expressed in a HEK293 cell expression system. MW = 42 kDa (monomer). This protein is enzymatically biotinylated using Avi-TagTM technology.
Keywords: BTLA, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein
Application: Immunotherapy studies
Reactivity: Human
MW: 42 kD
551.00€
Review
Droxinostat
Droxinostat

Item number: BPS-27620-2

Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 ?M and 1.46 ?M, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
Keywords: NS 41080, 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
Application: HDAC6/8 inhibitor
MW: 243.7 D
From 281.00€
Review
Entacapone
Entacapone

Item number: BPS-27621-2

Entacapone is a second-generation catechol-O-methyltransferase (COMT) inhibitor
Keywords: (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Application: COMT inhibitor
MW: 305.3 D
From 208.00€
Review
EPZ-6438
EPZ-6438

Item number: BPS-27626-3

EPZ-6438 is a potent and bio-available inhibitor of EZH2, the catalytic subunit of polycomb repressive complex 2 (PRC2) catalyzing the methylation of lysine 27 of histone H3 (H3K27), that inhibits the activity of human PRC2-containing wild-type EZH2 (Ki = 2.5 nM).
Keywords: E-7438,...
Application: EZH2 inhibitor
MW: 572.7 D
From 353.00€
Review
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