Proteins and Peptides

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Razor(TM) TEV Protease
Razor(TM) TEV Protease

Item number: BM-13002-1000

Ready for use. Recombinant TEV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TEV protease recognizes a linear epitope of the general form E-Xaa-Xaa-Y-Xaa-Q-(G/S), with cleavage occuring between Q and G or Q and S. The most commonly used sequence is ENLYFQG. This TEV protease contains a S219V...
Application: Protein cleavage, Tag removal
MW: 28,6 kD
Purity: >95%
Format: Solution
From 172.00€
Review
MOTS-c (human)
MOTS-c (human)

Item number: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in mice, Potential anti-obesity and anti-aging compound.
Application: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
Purity: >95%
Format: Solid
From 165.00€
Review
Thiostrepton
Thiostrepton

Item number: Cay19200-500

The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Thiostrepton is a natural peptide thiazole antibiotic that inhibits FoxM1 in mammalian cells, preventing the expression of FoxM1-regulated genes, which includes FoxM1 itself. Through this mechanism, thiostrepton prevents proliferation...
Application: FoxM1 inhibitor
CAS 1393-48-2
MW: 1664.9 D
Purity: >95%
Format: Solid
From 57.00€
Review
Malformin C
Malformin C

Item number: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates colchicine-induced M phase arrest in Jurkat cells (IC50 = 24...
Application: Antibacterial
CAS 59926-78-2
MW: 529.7 D
Purity: >95%
Format: Solid
From 124.00€
Review
Z-AEVD-FMK
Z-AEVD-FMK

Item number: Cay14987-500

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.
Application: Irreversible caspase-10 inhibitor
CAS 1135688-47-9
MW: 610.6 D
Purity: >95%
Format: Crystalline Solid
From 69.00€
Review
Ac-LETD-AFC
Ac-LETD-AFC

Item number: Cay14991-5

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Application: Fluorogenic Caspase-8 substrate
CAS 210345-02-1
MW: 729.7 D
Purity: >95%
Format: Crystalline Solid
From 78.00€
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IL-2, chicken recombinant (rchIL-2)
IL-2, chicken recombinant (rchIL-2)

Item number: RP0063C-005

Produced in Yeast. Amino acid sequence: ASLSSAKRKP LQTLIKDLEI LENIKNKIHL ELYTPTETQE CTQQTLQCYL GEVVTLKKET EDDTEIKEEF VTAIQNIEKN LKSLTGLNHT GSECKICEAN NKKKFPDFLH ELTNFVRYLQ.
Application: Bioassays
Expressed in: Yeast
Origin: Chicken
MW: 14 kD
Purity: >95%
Format: Lyophilized
From 194.00€
Review
AAF-CMK (trifluoroacetate salt)
AAF-CMK (trifluoroacetate salt)

Item number: Cay14461-5

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and...
Application: TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor
CAS 184901-82-4
MW: 453.8 D
Purity: >95%
Format: Crystalline Solid
From 62.00€
Review
MIF (human recombinant)
MIF (human recombinant)

Item number: Cay14493-100

Macrophage Migration Inhibitory Factor (MIF) is a small, pro-inflammatory cytokine. MIF signaling is important in septic shock, arthritis, colitis, and cardiovascular diseases. MIF counteracts glucocorticoid signaling, which would otherwise inhibit inflammation. Secreted MIF binds to CD74 receptors, which then couple to CD44, during monocyte recruitment. In addition to CD44...
Application: Enzyme activity, WB
Purity: >95% estimated by SDS-PAGE
Format: Purified
263.00€
Review
Razor(TM) TVMV Protease
Razor(TM) TVMV Protease

Item number: BM-13001-10000

Ready for use. Recombinant TVMV protease with an N-terminal His-tag for simple removal from the cleavage reaction by immobilization on metal-affinity resins. TVMV protease cleaves the sequence ETVRQS, with cleavage occuring between Q and S residues with high specifity. It is mainly used for removing affinity tags from peptides. Affinity tags are often applied to facilitate...
Application: Protein cleavage, Tag removal
MW: 27,4 kD
Purity: >95%
Format: Solution
From 172.00€
Review
Iberiotoxin
Iberiotoxin

Item number: Cay14608-100

Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium ion-activated potassium ion channels (BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by BKCa in excised membrane patches from bovine aortic smooth muscle with an IC50 value of 250 pM. It is also a...
Application: BKCa blocker
CAS 129203-60-7
MW: 4230.9 D
Purity: >95%
Format: Solid
249.00€
Review
CBX1 (human recombinant)
CBX1 (human recombinant)

Item number: Cay14768-100

The heterochromatin protein 1 (HP1) family, which consists of three isoforms HP1alpha (CBX5), HP1beta (CBX1), and HP1gamma (CBX3) are chromatin-associated proteins involved in gene regulation and heterochromatin formation. CBX proteins have an N-terminal chromodomain, a C-terminal chromoshadow domain (CSD), and a hinge domain which connects the two. Extensive...
Expressed in: E.coli
MW: 48,9 kD
Purity: >95%
Format: Solution
357.00€
Review
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