Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial... read more »
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Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

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TROP2 - CHO-K1 Recombinant Cell Line
TROP2 - CHO-K1 Recombinant Cell Line

Item number: BPS-78099

Recombinant CHO-K1 cells expressing the cell surface glycoprotein TROP2 (Trophoblast cell-surface antigen 2), ref. seq. NM_002353.2.
Keywords: GA733-1, TACSTD2, Cell surface glycoprotein Trop-2, Pancreatic carcinoma marker protein GA733-1, Tumor-associated calcium...
Application: Screening, Validating antibodies, CAR-T, Immunotherapy research, Drug discovery
Reactivity: Human
7,428.00€ *
Review
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GPC3 - CHO-K1 Recombinant Cell Line
GPC3 - CHO-K1 Recombinant Cell Line

Item number: BPS-78100

Recombinant CHO-K1 cells expressing GPC3 (Glypican 3), a cell surface proteoglycan bearing heparin-sulfate, ref. seq. NM_004484.2.
Keywords: OCI5, GPC3
Application: Screening, Validating antibodies, CAR-T, Immunotherapy research, Drug discovery
Reactivity: Human
7,428.00€ *
Review
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Human Mesothelin - CHO-K1 Recombinant Cell Line
Human Mesothelin - CHO-K1 Recombinant Cell Line

Item number: BPS-78132

Recombinant CHO-K1 cells expressing cleaved, mature human Mesothelin (MSLN) gene (GenBank Accession #NM_005823.5) under the control of cytomegalovirus (CMV) promoter. This cell line was generated by limited dilution and isolation of individual clones, which were screened based on MSLN expression to obtain a...
Keywords: MPF, MSLN
Application: MSLN-expressing target cells, MSLN CAR-T cells co-culture assays, Screening
Reactivity: Human
7,428.00€ *
Review
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Cas9-Expressing HCT116 Cell line - High expression
Cas9-Expressing HCT116 Cell line - High expression

Item number: BPS-78135-H

This cell line is a clonal derivative from the Cas9-Expressing HCT116 Cell Pool (BPS-78073). It was generated by limited dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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Cas9-Expressing Jurkat Cell line - High expression
Cas9-Expressing Jurkat Cell line - High expression

Item number: BPS-78136-H

This cell line is a clonal derivative from the Cas9-Expressing Jurkat Cell Pool (BPS-78070). It was generated by limited dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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Cas9-Expressing Neuro2a Cell line - High expression
Cas9-Expressing Neuro2a Cell line - High expression

Item number: BPS-78137-H

This cell line is a clonal derivative from the Cas9-Expressing Neuro2a Cell Pool (BPS-78087). It was generated by limited dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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Human EGFRvIII- CHO K1 Recombinant Cell Line (High or Low Expression)-78145-H
Human EGFRvIII- CHO K1 Recombinant Cell Line (High or Low...

Item number: BPS-78145-H

Recombinant hEGFRvIII-CHO K1 cell line stably expressing full-length human EGFRvIII receptor (accession number NP_001333870). Surface expression of hEGFRvIII was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of hEGFRvIII expression (High and Low) to mimic different...
Keywords: ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1
Application: EGFRvIII signaling inhibitor screening, Immuno-oncology research, Drug discovery
Reactivity: Human
7,428.00€ *
Review
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CD38 / BCMA / Firefly Luciferase CHO Recombinant Cell Line
CD38 / BCMA / Firefly Luciferase CHO Recombinant Cell Line

Item number: BPS-78148

Recombinant clonal stable CHO cell line constitutively expressing full length human CD38 protein (also known as ADPRC1, Genbank accession #NM_001775) and human BCMA protein (B-Cell Maturation Antigen or CD269, GenBank accession #NM_001192). This cell line was derived from our CHO-K1 Luciferase cells (BPS-79725),...
Keywords: T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1,...
Application: Validation
Reactivity: Human
10,274.00€ *
Review
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CD38 / CD19 / Firefly Luciferase CHO Recombinant Cell Line
CD38 / CD19 / Firefly Luciferase CHO Recombinant Cell Line

Item number: BPS-78149

Recombinant clonal stable CHO cell line constitutively expressing full length human CD38 protein (also known as ADPRC1, Genbank accession #NM_001775) and human CD19 protein (also known as B4 or CVID3, Genbank accession #NM_001770). This cell line was derived from our CHO-K1 Luciferase cells (BPS-79725), therefore it...
Keywords: T10, CD38, ADPRC 1, EC=3.2.2.6, EC=2.4.99.20, cADPr hydrolase 1, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1,...
Application: Validation
Reactivity: Human
10,274.00€ *
Review
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Cas9-Expressing MDA-MB-231 Cell Line (High or Low Expression)-78150-H
Cas9-Expressing MDA-MB-231 Cell Line (High or Low...

Item number: BPS-78150-H

This cell line is a clonal derivative from the Cas9-Expressing MDA-MB-231 Cell Pool (BPS-78069). It was generated by limited limiting dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a low- or high-expressing cell line. The expressed Cas9...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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Cas9-Expressing Raji Cell Line
Cas9-Expressing Raji Cell Line

Item number: BPS-78156

This cell line is a clonal derivative from the Cas9-Expressing Raji Cell Pool (BPS-78071). It was generated by limiting dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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Cas9-Expressing Daudi Cell Line
Cas9-Expressing Daudi Cell Line

Item number: BPS-78157

This cell line is a clonal derivative from the Cas9-Expressing Daudi Cell Pool (BPS-78089). It was generated by limiting dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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