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Cells

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial... read more »
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Cells

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

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IL-2-Luciferase Reporter (Luc) - Jurkat Cell Line
IL-2-Luciferase Reporter (Luc) - Jurkat Cell Line

Item number: BPS-60481

Human IL-2 reporter construct is stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by a human IL-2 promoter.
Keywords: IL2, IL-2, TCGF, Aldesleukin, Interleukin-2, T-cell growth factor
Application: Transcription activity screening
Reactivity: Human
7,919.00€ *
Review
CD155 / TCR Activator - CHO Recombinant Cell line
CD155 / TCR Activator - CHO Recombinant Cell line

Item number: BPS-60548

Recombinant CHO-K1 cells constitutively expressing human CD155 (Poliovirus receptor, Nectin-like protein 5, GenBank accession #NM_006505) and an engineered T cell receptor (TCR) activator.
Keywords: PVS, PVR, CD155, NECL-5, Poliovirus receptor, Nectin-like protein 5
Application: Activator / inhibitor screening (cellular context), CD155 antibody screening, TIGIT:CD155 interaction
Reactivity: Human
11,910.00€ *
Review
Normal Human Peripheral Blood Mononuclear Cells, Frozen
Normal Human Peripheral Blood Mononuclear Cells, Frozen

Item number: BPS-79059-2

Cryopreserved vial (30 x 10^6 cells or 100 x 10^6 cells, resp.) of freshly isolated primary human peripheral blood mononuclear cells (PBMCs) from a healthy donor, isolated from leukapheresis / apheresis samples using Ficoll gradient. After isolation, the PBMCs were stained to identify sub populations and evaluated...
Keywords: PBMC, primary cells
Application: Immunotherapy studies
From 241.00€ *
Review
PD-1 (Mouse) / NFAT - Reporter - Jurkat Recombinant Cell Line
PD-1 (Mouse) / NFAT - Reporter - Jurkat Recombinant Cell...

Item number: BPS-79762

Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of mouse PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_008798).
Keywords: CD279, mPD-1, Protein PD-1, Programmed cell death protein 1
Application: Inhibitor screening (cellular context), Ligand interaction studies
Reactivity: Mouse
11,910.00€ *
Review
PD-L1 (Mouse) / TCR Activator - CHO Recombinant Cell Line
PD-L1 (Mouse) / TCR Activator - CHO Recombinant Cell Line

Item number: BPS-79763

Recombinant CHO-K1 cells constitutively expressing mouse PD-L1 (Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7- H1), GenBank accession # NM_021893) and an engineered T cell receptor (TCR) activator.
Keywords: B7h1, B7-H1, Cd274, PD-L1, CD274, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Application: Inhibitor screening (cellular context), Ligand interaction studies, Antibody screening
Reactivity: Mouse
11,910.00€ *
Review
LAG3 / IL-2 Reporter - Jurkat Recombinant Cell Line
LAG3 / IL-2 Reporter - Jurkat Recombinant Cell Line

Item number: BPS-79813

Recombinant Jurkat T cell expressing firefly luciferase gene under the control of IL-2 response elements with constitutive expression of human LAG3 (lymphocyte-activation gene 3, CD223, GenBank Accession # NM_002286).
Keywords: FDC
Application: Activator / inhibitor screening (cellular context), Ligand interaction studies
Reactivity: Human
12,227.00€ *
Review
BCMA / GLuc - CHO Recombinant Cell Line
BCMA / GLuc - CHO Recombinant Cell Line

Item number: BPS-79830

Recombinant CHO-K1 cells constitutively expressing both the human BCMA protein (B-Cell Maturation Antigen or CD269, GenBank accession #NM_001192) and the Gaussia Luciferase (Î" Signal peptide). Surface expression of BCMA was confirmed by flow cytometry.
Keywords: BCM, CD269, TNFRSF17, B-cell maturation protein, Tumor necrosis factor receptor superfamily member 17
Application: Co-culture assays
Reactivity: Human
8,236.00€ *
Review
CD4+ T cells, Negatively Selected (Human)
CD4+ T cells, Negatively Selected (Human)

Item number: BPS-79752

Cryopreserved vial (10 x 10^6 cells) of CD4+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to...
Keywords: CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3
Application: Immunotherapy studies
Reactivity: Human
500.00€ *
Review
CD8+ T cells, Negatively Selected (Human)
CD8+ T cells, Negatively Selected (Human)

Item number: BPS-79753

Cryopreserved vial (10 x 10^6 cells) of CD8+ T cells that were negatively selected from freshly isolated primary human peripheral blood mononuclear cells (PBMCs). The PBMCs came from a healthy donor, and were isolated from whole blood or leukapheresis samples using a Ficoll gradient. Magnetic antibodies to...
Keywords: MAL, CD8a, CD8A, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
Application: Immunotherapy studies
Reactivity: Human
627.00€ *
Review
CSL Reporter - HEK293 Cell line
CSL Reporter - HEK293 Cell line

Item number: BPS-79754

The Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) stably integrated into HEK293 cells. Transfection of this cell line with a Notch expression vector and activation of the Notch pathway leads to expression of...
Keywords: TAN1, NOTCH1
Application: Notch signaling pathway activity monitoring, Inhibitor screening, SynNotch testing
Reactivity: Human
1,900.00€ *
Review
TrkA / SRE Reporter - HEK293 Recombinant Cell Line
TrkA / SRE Reporter - HEK293 Recombinant Cell Line

Item number: BPS-79798

Recombinant HEK-293 cells expressing firefly luciferase gene under the control of Serum Response Elements (SRE) with constitutive expression of human TrkA (Tropomyosin receptor kinase A, NTRK1, ref. seq. NM_002529.3).
Keywords: NTRK1, Trk-A, gp140trk, p140-TrkA, Tyrosine kinase receptor, Tyrosine kinase receptor A, Tropomyosin-related kinase A,...
Application: Inhibitor screening, Cellular context
Reactivity: Human
11,150.00€ *
Review
STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin)
STAT3 Reporter (Luc) - HEK293 Cell line (Puromycin)

Item number: BPS-79800-P

The STAT3 Reporter (Luc)-HEK293 cell line is designed for monitoring STAT3 signal transduction pathway. It contains a firefly luciferase gene driven by STAT3 response elements located upstream of the minimal TATA promoter. After activation by cytokines and growth factors, endogenous STAT3 binds to the DNA response...
Keywords: Acute-phase response factor, Signal transducer and activator of transcription 3
Application: STAT3 signaling pathway activity monitoring, Activator / inhibitor screening
Reactivity: Human
1,900.00€ *
Review
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