Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial... read more »
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Cells and Cell Lines

Cell culture and microbial culture techniques are essential for almost every aspect of biological research since modern microbiology started in the 19th century. The invention of microbial cultures of bacteria and yeast in sterile culture media allows selective growing of monoclonal cultures. From these cultures competent cells can be generated for the use in transformation. Cell culture colloquially refers to cultures of animal cells, in which we differentiate between ex vivo cultures and immortalized cell lines. Ex vivo cultures are derived from blood or organs and have a limited life span. Immortalized cell lines, however, are usually derived from tumors and proliferate indefinitely due to mutations in the cell cycle controls.

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CRISPRa (SAM) HEK293 Cell Line
CRISPRa (SAM) HEK293 Cell Line

Item number: BPS-78192

This cell line has been engineered for use with the CRISPR Synergistic Activation Mediator (SAM) system to induce transcriptional activation and expression of any gene of interest. Cells stably express a mutated dCas9 (Streptococcus pyogenes CRISPR associated protein 9), lacking any endonuclease activity, fused to...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1,
Application: CRISPR studies
Reactivity: Streptococcus Pyogenes Serotype M1
3,048.00€ *
Review
CRISPRa (SAM) HeLa Cell Line
CRISPRa (SAM) HeLa Cell Line

Item number: BPS-78193

This cell line has been engineered for use with the CRISPR Synergistic Activation Mediator (SAM) system to induce transcriptional activation and expression of any gene of interest. Cells stably express a mutated dCas9 (Streptococcus pyogenes CRISPR associated protein 9), lacking any endonuclease activity, fused to...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1,
Application: CRISPR studies
Reactivity: Streptococcus Pyogenes Serotype M1
3,048.00€ *
Review
CRISPRa (SAM) HepG2 Cell Line
CRISPRa (SAM) HepG2 Cell Line

Item number: BPS-78194

This cell line has been engineered for use with the CRISPR Synergistic Activation Mediator (SAM) system to induce transcriptional activation and expression of any gene of interest. Cells stably express a mutated dCas9 (Streptococcus pyogenes CRISPR associated protein 9), lacking any endonuclease activity, fused to...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1,
Application: CRISPR studies
Reactivity: Streptococcus Pyogenes Serotype M1
3,048.00€ *
Review
GLP-1R/CRE (Luc) Reporter - HEK293 Recombinant Cell Line
GLP-1R/CRE (Luc) Reporter - HEK293 Recombinant Cell Line

Item number: BPS-78176

Recombinant HEK293 cells expressing firefly luciferase gene under the control of cAMP response element (CRE) with constitutive expression of human GLP-1R (Glucagon-like peptide 1 receptor, accession number BC113493). GLP-1R, a member of the class B family of G protein-coupled receptors (GPCRs) primarily found in...
Keywords: GLP1R, GLP-1R, GLP-1-R, GLP-1 receptor, Glucagon-like peptide 1 receptor,
Application: Agonist screening in cellular context
Reactivity: Human
10,274.00€ *
Review
Cas9-Expressing MCF7 Cell Pool
Cas9-Expressing MCF7 Cell Pool

Item number: BPS-78179

Cas9 (Streptococcus pyogenes CRISPR associated protein 9) is an endonuclease enzyme that, when recruited to a specific DNA sequence by the sgRNA (single guide RNA), introduces a double stranded break into the DNA. This double stranded break is repaired in mammalian cells either through Non-Homologous End Joining or...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1,
Application: Quick knock-out cell pool / cell line generation, SgRNA screening
Reactivity: Streptococcus Pyogenes Serotype M1
998.00€ *
Review
BCMA / CD20 / Firefly Luciferase CHO Cell Line
BCMA / CD20 / Firefly Luciferase CHO Cell Line

Item number: BPS-78185

Clonal stable CHO cell line constitutively expressing full length human BCMA protein (also known as CD269 or TNFRSF17, Genbank accession #NM_001192) and human CD20 protein (also known as MS4A1 or FMC7, Genbank accession #NM_021950). This cell line was derived from our CHO-K1 Luciferase cells BPS-79725, therefore it...
Keywords: BCM, CD269, TNFRSF17, B-cell maturation protein, Tumor necrosis factor receptor superfamily member 17,
Application: CAR-T studies
Reactivity: Human
11,289.00€ *
Review
CD19 / CD20 / Firefly Luciferase CHO Cell Line
CD19 / CD20 / Firefly Luciferase CHO Cell Line

Item number: BPS-78186

Clonal stable CHO cell line constitutively expressing full length human CD19 protein (also known as CVID3, Genbank accession #NM_001770) and human CD20 protein (also known as MS4A1 and FMC7, Genbank accession #NM_021950). This cell line was derived from our CHO-K1 Luciferase cells BPS-79725, therefore it also...
Keywords: CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen...
Application: CAR-T studies
Reactivity: Human
11,289.00€ *
Review
TROP2 - CHO-K1 Recombinant Cell Line
TROP2 - CHO-K1 Recombinant Cell Line

Item number: BPS-78099

Recombinant CHO-K1 cells expressing the cell surface glycoprotein TROP2 (Trophoblast cell-surface antigen 2), ref. seq. NM_002353.2.
Keywords: GA733-1, TACSTD2, Cell surface glycoprotein Trop-2, Pancreatic carcinoma marker protein GA733-1, Tumor-associated calcium...
Application: Screening, Validating antibodies, CAR-T, Immunotherapy research, Drug discovery
Reactivity: Human
7,428.00€ *
Review
GPC3 - CHO-K1 Recombinant Cell Line
GPC3 - CHO-K1 Recombinant Cell Line

Item number: BPS-78100

Recombinant CHO-K1 cells expressing GPC3 (Glypican 3), a cell surface proteoglycan bearing heparin-sulfate, ref. seq. NM_004484.2.
Keywords: OCI5, GPC3
Application: Screening, Validating antibodies, CAR-T, Immunotherapy research, Drug discovery
Reactivity: Human
7,428.00€ *
Review
Human Mesothelin - CHO-K1 Recombinant Cell Line
Human Mesothelin - CHO-K1 Recombinant Cell Line

Item number: BPS-78132

Recombinant CHO-K1 cells expressing cleaved, mature human Mesothelin (MSLN) gene (GenBank Accession #NM_005823.5) under the control of cytomegalovirus (CMV) promoter. This cell line was generated by limited dilution and isolation of individual clones, which were screened based on MSLN expression to obtain a...
Keywords: MPF, MSLN
Application: MSLN-expressing target cells, MSLN CAR-T cells co-culture assays, Screening
Reactivity: Human
7,428.00€ *
Review
Cas9-Expressing HCT116 Cell line - High expression
Cas9-Expressing HCT116 Cell line - High expression

Item number: BPS-78135-H

This cell line is a clonal derivative from the Cas9-Expressing HCT116 Cell Pool (BPS-78073). It was generated by limited dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a high-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
Cas9-Expressing HCT116 Cell line - Low expression
Cas9-Expressing HCT116 Cell line - Low expression

Item number: BPS-78135-L

This cell line is a clonal derivative from the Cas9-Expressing HCT116 Cell Pool (BPS-78073). It was generated by limited dilution of the original pool and isolation of individual clones, which were screened based on Cas9 expression to obtain a low-expressing cell line. The expressed Cas9 protein includes a...
Keywords: SpCas9, SpyCas9, SPy_1046, CRISPR-associated endonuclease Cas9/Csn1
Application: Knock-out generation, SgRNA screen implementation
7,428.00€ *
Review
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