Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

More information at: www.caymanchem.com

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TBARS Assay Kit
TBARS Assay Kit

Item number: Cay10009055-96

Oxidative stress in the cellular environment results in the formation of highly reactive and unstable lipid hydroperoxides. Decomposition of the unstable peroxides derived from PUFAs results in the formation of malondialdehyde (MDA), which can be quantified colorimetrically following its controlled reaction with...
Keywords: Thiobarbituric Acid Reactive Substances
Application: Lipid peroxidation
232.00€ *
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Glucose Colorimetric Assay Kit
Glucose Colorimetric Assay Kit

Item number: Cay10009582-192

Glucose, a monosaccharide (or simple sugar), is the most important carbohydrate in biology. Transported via the blood stream, it is the primary source of energy for the body's cells. Glucose level is tightly regulated in the human body. Failure to maintain blood glucose in the normal range leads to conditions of...
Application: Glucose detection
219.00€ *
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Phagocytosis Assay Kit (IgG FITC)
Phagocytosis Assay Kit (IgG FITC)

Item number: Cay500290-1

Cayman's Phagocytosis Assay Kit (IgG FITC) employs latex beads coated with fluorescently-labeled rabbit IgG as a probe for the measurement of the phagocytic process in vitro. The engulfed fluorescent beads can be detected using a fluorescence microscope, allowing kinetic studies of phagocytosis at the single-cell...
Application: FC
313.00€ *
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Creatinine (urinary) Colorimetric Assay Kit
Creatinine (urinary) Colorimetric Assay Kit

Item number: Cay500701-96

Creatine is synthesized in kidney, liver, and pancreas and transported to muscle and brain where it is phosphorylated to phosphocreatine. Some free creatine in muscle is converted to creatinine. The amount of creatinine produced is proportional to an individual's muscle mass. In the absence of renal disease, the...
Application: Creatinine measurement
From 102.00€ *
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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
Citrullinated Histone H3 (Clone 11D3) ELISA Kit

Item number: Cay501620-96

Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore...
Keywords: CitH3 (Clone 11D3) EIA Kit
Application: ELISA
619.00€ *
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Nitrate/Nitrite Colorimetric Assay Kit
Nitrate/Nitrite Colorimetric Assay Kit

Item number: Cay780001-192

The Cayman Chemical Nitrate/Nitrite Assay Kit provides an accurate and convenient method for measurement of total nitrate/nitrite concentration in a simple two-step process. The first step is the conversion of nitrate to nitrite utilizing nitrate reductase. The second step is the addition of the Griess Reagents...
Keywords: Nitric Oxide Metabolite Detection Kit
Application: Nitrate detection, Nitrite detection
232.00€ *
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CHIR99021
CHIR99021

Item number: Cay13122-10

Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein...
Keywords: CT 99021,...
Application: GSK3alpha and GSK3beta inhibitor
CAS 252917-06-9
MW: 465.3 D
From 32.00€ *
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Prostaglandin E2
Prostaglandin E2

Item number: Cay14010-1

PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Keywords: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
From 25.00€ *
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15-deoxy-Delta12,14-Prostaglandin J2
15-deoxy-Delta12,14-Prostaglandin J2

Item number: Cay18570-1

15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
Keywords: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Application: Bioactive lipid assays
CAS 87893-55-8
MW: 316.4 D
From 32.00€ *
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Cholesterol Fluorometric Assay Kit
Cholesterol Fluorometric Assay Kit

Item number: Cay10007640-96

Cholesterol, particularly in the form of low density lipoproteins (LDL), is well understood to be associated with increased risk of coronary heart disease. The measurement of cholesterol is one of the most common tests performed in the clinical laboratory setting. However, simple and easy assays for cholesterol in...
Application: Cholesterol quantification
From 185.00€ *
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Tamoxifen
Tamoxifen

Item number: Cay13258-1

There are two homologous nuclear receptors for the hormone 17beta-estradiol (estrogen), commonly called ERalpha and ERbeta. Receptor activation leads to the formation of homo- and hetero-dimers, which in turn interact with accessory proteins to regulate gene transcription. Tamoxifen is a selective estrogen receptor...
Keywords: 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine
Application: Estrogen receptor modulator
CAS 10540-29-1
MW: 371.5 D
From 57.00€ *
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SB-431542
SB-431542

Item number: Cay13031-25

SB-431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. SB-431542 specifically blocks Smad signaling, reducing gene...
Keywords: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide, hydrate
Application: ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor
CAS 301836-41-9
MW: 384.4 D
From 32.00€ *
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