Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Item number: Cay10009542-100

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Keywords: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Application: Antibiotic
CAS 13803-65-1
MW: 462.9 D
From 45.00€ *
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
From 332.00€ *
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Malformin C
Malformin C

Item number: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
Keywords: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Application: Antibacterial
CAS 59926-78-2
MW: 529.7 D
From 232.00€ *
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Lipid Hydroperoxide (LPO) Assay Kit (96 well)
Lipid Hydroperoxide (LPO) Assay Kit (96 well)

Item number: Cay705003-96

Quantification of lipid peroxidation is essential to assess the role of oxidative injury in pathophysiological disorders. Lipid peroxidation results in the formation of highly reactive and unstable hydroperoxides of both saturated and unsaturated lipids. Our Lipid Hydroperoxide Assay Kit measures the hydroperoxides...
Application: LPO quantification
744.00€ * 669.60€ *
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Estradiol ELISA Kit
Estradiol ELISA Kit

Item number: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Keywords: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Application: Competitive ELISA
From 250.00€ *
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Oligomycin Complex
Oligomycin Complex

Item number: Cay11341-5

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins...
Application: ATP synthase inhibitor, Apoptosis inducer
CAS 1404-19-9
MW: 789,3 D
From 32.00€ *
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Phagocytosis Assay Kit (IgG FITC)
Phagocytosis Assay Kit (IgG FITC)

Item number: Cay500290-1

Cayman's Phagocytosis Assay Kit (IgG FITC) employs latex beads coated with fluorescently-labeled rabbit IgG as a probe for the measurement of the phagocytic process in vitro. The engulfed fluorescent beads can be detected using a fluorescence microscope, allowing kinetic studies of phagocytosis at the single-cell...
Application: FC
313.00€ *
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Nrf2 Transcription Factor Assay Kit
Nrf2 Transcription Factor Assay Kit

Item number: Cay600590-96

Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that plays a key role in maintaining redox homeostasis via its interaction with a cysteine-rich protein Kelch-like ECH-associated protein 1 (Keap1). In resting cells, Nrf2 and Keap1 form a tight complex, which is targeted for degradation by...
Keywords: GABPA, NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2,...
Application: DNA binding assay
532.00€ *
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Pyruvate Assay Kit
Pyruvate Assay Kit

Item number: Cay700470-96

Pyruvate (pyruvic acid) is a key intermediate in cellular metabolic pathways and is derived primarily from glucose via glycolysis. Abnormal blood pyruvate levels are reported in a number of disorders including shock, liver disease, congestive heart failure, diabetes mellitus, thiamine deficiency, and metabolic...
Keywords: Pyruvic Acid Assay Kit
Application: Pyruvate quantification
318.00€ *
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Glutathione Peroxidase Assay Kit
Glutathione Peroxidase Assay Kit

Item number: Cay703102-96

Glutathione peroxidase (GPX) catalyzes the reduction of hydroperoxides, including hydrogen peroxides, by reduced glutathione and functions to protect the cell from oxidative damage. With the exception of phospholipid-hydroperoxide GPX, a monomer, all of the GPX enzymes are tetramers of four identical subunits. Each...
Keywords: EC=1.11.1.9, GPX
Application: GTx activity detection
357.00€ * From 321.30€ *
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Glutathione Reductase Assay Kit
Glutathione Reductase Assay Kit

Item number: Cay703202-96

Glutathione reductase (GR, EC 1.6.4.2) is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized glutathione (GSSG) to glutathione (GSH). This enzyme is essential for the GSH redox cycle which maintains adequate levels of reduced cellular GSH. A high GSH/GSSG ratio is essential for protection...
Keywords: GR, GSR, GLUR, GRase, EC=1.8.1.7
Application: GR activity detection
282.00€ * 253.80€ *
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Glutathione S-Transferase Assay Kit
Glutathione S-Transferase Assay Kit

Item number: Cay703302-96

Glutathione S-transferases (GSTs) are ubiquitous multifunctional enzymes, which play a key role in cellular detoxification. The enzymes protect cells against toxicants by conjugating them to glutathione, thereby neutralizing their electrophilic sites, and rendering the products more water-soluble. The glutathione...
Keywords: GST
Application: GST activity detection
282.00€ * 253.80€ *
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