Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
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GSK4027 Item number: Cay23421-10
GSK4027 is a p300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) bromodomain inhibitor (Ki = 1.4 nM, IC50 = 60 nM in a chromatin engagement assay). It is greater than 18,000-fold selective for PCAF and GCN5 over BET family bromodomains and greater than 70-fold selective over other bromodomain...
| Keywords: | 4-bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-3(2H)-pyridazinone |
| Application: | PCAF / GCN5 bromodomain inhibitor |
| CAS | 2079896-25-4 |
| MW: | 377.3 D |
From 44.00€ *
5-Hydroxymethylfurfural Item number: Cay27835-5
5-Hydroxymethylfurfural is a furanic compound derived from the degradation of sugars. It can be derived from reducing sugars via acid-catalyzed degradation or the Maillard reaction during the heating and storage of foods. 5-Hydroxymethylfurfural is an intermediate in the synthesis of a variety of compounds including...
| Keywords: | HMF, NSC 40738, 5-(hydroxymethyl)-2-furancarboxaldehyde |
| Application: | Radical scavenger |
| CAS | 67-47-0 |
| MW: | 126.1 D |
From 32.00€ *
Arachidic Acid-d2 Item number: Cay28083-5
Arachidic acid-d2 is intended for use as an internal standard for the quantification of arachidic acid (Cay-9000339, Cay-21906) by GC- or LC-MS. Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by...
| Keywords: | Arachic Acid-d2, Eicosanoate-d2, Icosanoic Acid-d2, eicosanoic-2,2-d2 acid |
| Application: | GC-MS, LC-MS, Internal standard, Quantification, Saturated long-chain fatty acid |
| CAS | 232600-70-3 |
| MW: | 314.5 D |
From 99.00€ *
Ferrostatin-1 Item number: Cay17729-5
Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Cay-17754, EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 µM. Ferrostatin-1 (0.5 µM) inhibits erastin-induced...
| Keywords: | Fer-1, 3-amino-4-(cyclohexylamino)-benzoic acid, ethyl ester |
| Application: | Ferroptosis inhibitor |
| CAS | 347174-05-4 |
| MW: | 262.4 D |
From 62.00€ *
Stearidonic Acid ethyl ester Item number: Cay10006856-1
Stearidonic acid (18:4omega-3) is a rare polyunsaturated fatty acid of the omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. It is present in certain natural oils such as echium and black currant seed, and to the extent that these oils are incorporated into...
| Keywords: | Ethyl Stearidonate, Moroctic Acid ethyl ester, 6Z,9Z,12Z,15Z-octadecatetraenoic acid, ethyl ester |
| Application: | Bioactive lipid assays |
| CAS | 119798-44-6 |
| MW: | 304.5 D |
From 57.00€ *
Prostaglandin E2-d9 Item number: Cay10581-250
PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
| Keywords: | Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid |
| Application: | Standard |
| CAS | 1356347-42-6 |
| MW: | 361.5 D |
From 64.00€ *
BAPTA Item number: Cay11706-100
BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
| Keywords: | N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-glycine |
| Application: | Calcium chelator |
| CAS | 85233-19-8 |
| MW: | 476.4 D |
From 32.00€ *
Streptozotocin Item number: Cay13104-100
Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and...
| Keywords: | Estreptozocin, NSC 37917, NSC 85998, STZ, U 9889, Zanosar, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose |
| Application: | Diabetes inducer, NO donor |
| CAS | 18883-66-4 |
| MW: | 265.2 D |
From 32.00€ *
Oleoyl Serinol Item number: Cay13637-100
Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
| Keywords: | N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide |
| Application: | GPR119 agonist |
| CAS | 72809-08-6 |
| MW: | 355.6 D |
From 42.00€ *
D-(-)-3-Phosphoglyceric Acid (sodium salt) Item number: Cay20123-10
D-(-)-3-Phosphoglyceric acid is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine. It also has numerous roles as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
| Keywords: | 2R-hydroxy-3-(phosphonooxy)-propanoic acid, disodium salt |
| Application: | Glycolysis intermediate, Serine precursor |
| CAS | 80731-10-8 |
| MW: | 230 D |
From 19.00€ *
N6-Benzyladenine Item number: Cay21711-25
N6-Benzyladenine (6-BAP) is a synthetic cytokinin that stimulates plant growth and regulates de novo bud development, leaf expansion, delay of senescence, and chloroplast formation in plants. 6-BAP inhibits respiratory kinase in plants and increases post-harvest life of green vegetables. 6-BAP also increases lipid...
| Keywords: | 6-BAP, N6-Benzylaminopurine, NSC 40818, SQ 4,609, N-(phenylmethyl)-9H-purin-6-amine |
| Application: | Synthetic cytokinin, Plant growth stimulator, Respiratory kinase inhibitor |
| CAS | 1214-39-7 |
| MW: | 225.3 D |
From 42.00€ *
Yoda1 Item number: Cay21904-1
Yoda1 is a Piezo1 ion channel agonist (EC50s = 17.1 and 26.6 µM for murine and human Piezo1-transfected HEK293T cells, respectively). It is selective for Piezo1 as it elicits Ca2+ flux in Piezo1- but not Piezo2-transfected HEK293T cells. Yoda1 slows the inactivation phase of murine Piezo1 transient currents and...
| Keywords: | 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-pyrazine |
| Application: | Piezo1 agonist |
| CAS | 448947-81-7 |
| MW: | 355.3 D |
From 33.00€ *
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