Products from Cayman

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

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TCEP (hydrochloride)
TCEP (hydrochloride)

Item number: Cay14329-1

TCEP is an odorless, selective, and water-soluble reducing agent that is commonly used in many laboratory applications. It is commonly used to rapidly reduce protein and peptide disulfide bonds. TCEP can be combined with proteases to simultaneously reduce and digest proteins prior to mass spectrometry in order to dramatically increase sequence coverage. It has also been used...
Application: Water-soluble reducing agent
CAS 51805-45-9
MW: 286.7 D
Purity: >98%
Format: Crystalline Solid
44.00€
Review
SF7-AM
SF7-AM

Item number: Cay14623-1

Application: H2S fluorescent probe
CAS 1416872-50-8
MW: 685.6 D
187.00€
Review
Primary Prostaglandin Metabolite LC-MS Mixture
Primary Prostaglandin Metabolite LC-MS Mixture

Item number: Cay19300-1

This mixture contains the first prominent metabolites of the primary prostaglandins (PGs) PGE2, PGD2, and PGF2alpha. The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of calibrators...
Application: LC-MS
Format: Solution
282.00€
Review
Lipoxin LC-MS Mixture
Lipoxin LC-MS Mixture

Item number: Cay19412-1

This mixture contains several lipoxins and their precursor, arachidonic acid (Cay-90010). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of calibrators and QC standards and/or used...
Application: LC-MS, Calibrator / standard preparation
Format: Solution
357.00€
Review
Arachidonic Acid Oxylipin LC-MS Mixture
Arachidonic Acid Oxylipin LC-MS Mixture

Item number: Cay20666-1

The arachidonic acid oxylipin LC-MS mixture contains oxylipin metabolites derived from arachidonic acid (Cay-90010). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of calibrators...
Application: MS
Format: Solution
544.00€
Review
Leukotriene B4 Pathway LC-MS Mixture
Leukotriene B4 Pathway LC-MS Mixture

Item number: Cay22640-1

The leukotriene B4 pathway LC-MS mixture contains 5-lipoxygenase pathway metabolites derived from arachidonic acid (Cay-90010). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be used as a system suitability standard...
Application: MS
Format: Solution
388.00€
Review
Human Fibrinogen (PAD4 Citrullinated)
Human Fibrinogen (PAD4 Citrullinated)

Item number: Cay400076-1

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis (RA) produce antibodies that bind citrullinated human...
Application: WB
Format: Solid
407.00€
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beta-Hydroxybutyrate (Ketone Body) Colorimetric Assay Kit
beta-Hydroxybutyrate (Ketone Body) Colorimetric...

Item number: Cay700190-96

beta-Hydroxybutyrate (beta-HB, 3-hydroxybutyric acid) is a "ketone body" which is produced in the liver, mainly from the oxidation of fatty acids, and is exported to peripheral tissues for use as an energy source. The term 'ketone body' refers to three molecules, acetoacetate, beta-HB, and acetone. beta-HB and acetoacetate transport energy from the liver to the other tissues...
Application: Beta-HB measurement
Format: Homog.
282.00€
Review
tetranor-12(S)-HETE
tetranor-12(S)-HETE

Item number: Cay10007207-25

12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major beta-oxidation product resulting from peroxisomal...
Application: Bioactive lipid assays
CAS 121842-79-3
MW: 266.4 D
Purity: >98%
Format: Solution
From 165.00€
Review
19(S)-HETE
19(S)-HETE

Item number: Cay10007766-25

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both...
Application: Bioactive lipid assays
CAS 115461-40-0
MW: 320.5 D
Purity: >98%
Format: Solution
From 150.00€
Review
Bortezomib
Bortezomib

Item number: Cay10008822-5

Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell cycle arrest and apoptosis in cancer cell lines and has...
Application: Proteasome subunit beta type-1/5 inhibitor
CAS 179324-69-7
MW: 384.2 D
Purity: >95%
Format: Crystalline Solid
From 32.00€
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9-OxoOTrE
9-OxoOTrE

Item number: Cay10009215-25

9-OxoOTrE is produced by the oxidation of 9-HpOTrE. 9-OxoOTrE exhibits antimicrobial activity against plant pathogenic microorganisms including bacteria and fungi.
Application: Bioactive lipid assays
CAS 125559-74-2
MW: 292.4 D
Purity: >95%
Format: Solution
From 82.00€
Review
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