Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

More information at: www.caymanchem.com

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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Item number: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Keywords: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132.00€ *
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Estradiol ELISA Kit
Estradiol ELISA Kit

Item number: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Keywords: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Application: Competitive ELISA
From 250.00€ *
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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Item number: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Keywords: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158.00€ *
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
From 332.00€ *
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Malformin C
Malformin C

Item number: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
Keywords: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Application: Antibacterial
CAS 59926-78-2
MW: 529.7 D
From 232.00€ *
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Lipid Hydroperoxide (LPO) Assay Kit (96 well)
Lipid Hydroperoxide (LPO) Assay Kit (96 well)

Item number: Cay705003-96

Quantification of lipid peroxidation is essential to assess the role of oxidative injury in pathophysiological disorders. Lipid peroxidation results in the formation of highly reactive and unstable hydroperoxides of both saturated and unsaturated lipids. Our Lipid Hydroperoxide Assay Kit measures the hydroperoxides...
Application: LPO quantification
744.00€ * 669.60€ *
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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Item number: Cay10009542-100

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Keywords: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Application: Antibiotic
CAS 13803-65-1
MW: 462.9 D
From 45.00€ *
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Imipenem (hydrate)
Imipenem (hydrate)

Item number: Cay16039-100

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
Keywords: N-Formimidoyl Thienamycin,...
Application: Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor
CAS 74431-23-5
MW: 317.4 D
From 57.00€ *
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COX (ovine/human) Inhibitor Screening Assay Kit
COX (ovine/human) Inhibitor Screening Assay Kit

Item number: Cay560131-96

Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) enzymes contain both cyclooxygenase and peroxidase activities. COX catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins, the conversion of arachidonic acid to PGH2. It is now well established that...
Application: COX inhibitor screening
469.00€ *
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Prostaglandin E2-d4
Prostaglandin E2-d4

Item number: Cay314010-50

Prostaglandin E2-d4 (PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated...
Keywords: Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Application: Standard
CAS 34210-10-1
MW: 356.5 D
From 67.00€ *
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Methotrexate
Methotrexate

Item number: Cay13960-50

Methotrexate (MTX) is similar in structure to folic acid (Cay-20515) and aminopterin (Cay-21802). It acts by inhibiting the metabolism of folic acid and blocking key enzymes in the synthesis of purines and pyrimidines required for cell proliferation. MTX is known to induce adenosine release, which mediates many of...
Keywords: Amethopterin, CL 14,377, EMT 25299, MTX, NSC 740, R 9985,...
Application: Antineoplastic agent, Dihydrofolate reductase inhibitor
CAS 59-05-2
MW: 454.4 D
From 23.00€ *
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Acetyl Coenzyme A (sodium salt)
Acetyl Coenzyme A (sodium salt)

Item number: Cay16160-10

Acetyl Coenzyme A (acetyl-CoA), the thioester of CoA (Cay-16147) and acetic acid, is a pivotal molecule in biological systems. Foremost, it serves as a source of carbon for the Krebs cycle, for the synthesis of fatty acids, and for isoprenoid-based protein modifications. Acetyl-CoA also serves as an intermediate in...
Keywords: Acetyl-CoA, S-acetate coenzyme A, trisodium salt
Application: Krebs cycle intermediate
CAS 102029-73-2
MW: 878.5 D
From 32.00€ *
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