Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Ionomycin (calcium salt) Item number: Cay11932-1
Ionomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores. It is used as a research tool to raise the intracellular level of calcium, to study calcium transport across biological membranes, and to stimulate the intracellular production of cytokines. This...
| Keywords: | 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura... |
| Application: | Calcium ionophore |
| CAS | 56092-82-1 |
| MW: | 747.1 D |
From 32.00€ *
Arachidonic Acid-d11 Item number: Cay10006758-100
Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
| Keywords: | AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Application: | GC-MS, LC-MS, Internal standard |
| MW: | 315.5 D |
From 48.00€ *
(±)-EX-527 Item number: Cay10009798-5
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7 cells.
| Keywords: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Application: | SIRT1 inhibitor |
| CAS | 49843-98-3 |
| MW: | 248.7 D |
From 32.00€ *
Imipenem (hydrate) Item number: Cay16039-100
Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
| Keywords: | N-Formimidoyl Thienamycin,... |
| Application: | Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor |
| CAS | 74431-23-5 |
| MW: | 317.4 D |
From 57.00€ *
Prostaglandin A1 Item number: Cay10010-50
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
| Keywords: | PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 14152-28-4 |
| MW: | 336.5 D |
From 35.00€ *
(+)-Abscisic Acid Item number: Cay10073-1
Abscisic acid (ABA) is a plant hormone with diverse roles in disease resistance, plant development, and response to stresses (water, salt, temperature, and pathogens). It is also produced by some plant pathogenic fungi. In addition to key roles in regulating stomatal closing, seed dormancy, and cell division, ABA...
| Keywords: | (+)-ABA, Dormin, 5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2Z,4E-pentadienoic acid |
| Application: | Plant hormone |
| CAS | 21293-29-8 |
| MW: | 264.3 D |
From 20.00€ *
2-NBDG Item number: Cay11046-1
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Cay-23733), but not L-glucose (Cay-20829) or sucrose, in E. coli. It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies. 2-NBDG displays excitation/emission maxima of...
| Keywords: | NBD-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose |
| Application: | Deoxyglucose analog |
| CAS | 186689-07-6 |
| MW: | 342.3 D |
From 44.00€ *
Disuccinimidyl Suberate Item number: Cay13008-50
Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.
| Keywords: | DSS, NSC 340008, octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester |
| Application: | Cross-linking reagent |
| CAS | 68528-80-3 |
| MW: | 368.3 D |
From 9.00€ *
Temozolomide Item number: Cay14163-100
Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells. TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the...
| Keywords: | CCRG 81045, MB 39831, Methazolastone, NSC 362856, Temodal, TMZ,... |
| Application: | DNA alkylating agent, Apoptosis inducer |
| CAS | 85622-93-1 |
| MW: | 194.2 D |
From 49.00€ *
6-keto Prostaglandin F1alpha-d4 Item number: Cay315210-25
6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
| Keywords: | 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid |
| Application: | Standard |
| CAS | 82414-64-0 |
| MW: | 374.5 D |
From 65.00€ *
2-Arachidonoyl Glycerol-d5 Item number: Cay362162-100
2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
| Keywords: | 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester |
| Application: | Standard |
| MW: | 383.6 D |
From 65.00€ *
2-Arachidonoyl Glycerol Item number: Cay62160-25
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
| Keywords: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 53847-30-6 |
| MW: | 378.6 D |
From 32.00€ *
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