Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, is helping make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative injury, endocrinology, and much more. Cayman Chemical specializes in assay kits for the measurement of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

More information at: www.caymanchem.com

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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Item number: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Keywords: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158.00€ *
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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Item number: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Keywords: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Application: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132.00€ *
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Item number: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Keywords: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Application: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
From 332.00€ *
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SIN-1 (chloride)
SIN-1 (chloride)

Item number: Cay82220-50

As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
Keywords: 3-Morpholino-sydnonimine, Linsidomine, 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride
Application: Peroxynitrite generation
CAS 16142-27-1
MW: 206.6 D
From 18.00€ *
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Malformin C
Malformin C

Item number: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
Keywords: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Application: Antibacterial
CAS 59926-78-2
MW: 529.7 D
From 232.00€ *
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COVID-19 Research
Remdesivir
Remdesivir

Item number: Cay30354-5

Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
Keywords: GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with...
Application: GS-441524 prodrug, SARS type antiviral
CAS 1809249-37-3
MW: 602.6 D
From 219.00€ *
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Imipenem (hydrate)
Imipenem (hydrate)

Item number: Cay16039-100

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
Keywords: N-Formimidoyl Thienamycin,...
Application: Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor
CAS 74431-23-5
MW: 317.4 D
From 57.00€ *
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Phagocytosis Assay Kit (IgG FITC)
Phagocytosis Assay Kit (IgG FITC)

Item number: Cay500290-1

Cayman's Phagocytosis Assay Kit (IgG FITC) employs latex beads coated with fluorescently-labeled rabbit IgG as a probe for the measurement of the phagocytic process in vitro. The engulfed fluorescent beads can be detected using a fluorescence microscope, allowing kinetic studies of phagocytosis at the single-cell...
Application: FC
313.00€ *
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Maresin 1 ELISA Kit
Maresin 1 ELISA Kit

Item number: Cay501150-96

Maresins (macrophage mediators in resolving inflammation) are members of a class of potent anti-inflammatory and pro-resolving mediators that are synthesized by macrophages in the presence of docosahexaenoic acid (DHA). Maresin 1 (MaR1) is produced via oxidation of endogenous DHA by 12-lipoxygenase. MaR1 has been...
Keywords: 7(R)-MaR1, 7(R)-Maresin 1 EIA, MaR1
Application: ELISA
Reactivity: Broad
494.00€ *
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Corticosterone ELISA Kit
Corticosterone ELISA Kit

Item number: Cay501320-96

Corticosterone is a glucocorticoid produced by the adrenal cortex in response to ACTH (corticotropic hormone) and is the precursor to aldosterone. The production of glucorcorticoids is increased by stress, therefore, corticosterone can be used as a biomarker of stress. Biologists often measure corticosterone in...
Keywords: 11beta,21-DHP, 11beta,21-dihydroxy Progesterone, 17-deoxy Cortisol, Corticosterone EIA Kit
Application: ELISA
307.00€ * From 276.30€ *
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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
Citrullinated Histone H3 (Clone 11D3) ELISA Kit

Item number: Cay501620-96

Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore...
Keywords: CitH3 (Clone 11D3) EIA Kit
Application: ELISA
619.00€ *
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Prostaglandin E Metabolite ELISA Kit
Prostaglandin E Metabolite ELISA Kit

Item number: Cay514531-96

Prostaglandin E2 (PGE2) is produced by a variety of cell types which, in general, do not contain the enzymes required for metabolism of PGE2. Thus, cultured endothelial cells or osteoblasts will release PGE2 into the culture medium, where it will accumulate without appreciable metabolism. The direct assay of PGE2...
Keywords: PGE Metabolite EIA Kit, PGEM
Application: ELISA
From 344.00€ *
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