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Item number: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
|Application:||Caspase-3 substrate, Caspase-7 substrate|
Item number: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Item number: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
|Keywords:||3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine|
|Application:||TR Delta alpha1 activator|
From 82.00€ *
Item number: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
From 24.00€ *
Item number: Cay33115-1
Eledoisin-related peptide is a hexapeptide fragment of eledoisin (Cay-28810), an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist. It induces contractions in isolated guinea pig ileum, as well as alpha-amylase release from rat parotid gland slices, in a concentration-dependent manner....
|Keywords:||Eledoisin Hexapeptide, Eledoisin RP, KFIGLM-NH2, Lys-Phe-Ile-Gly-Leu-Met-NH2,...|
|Application:||Eledoisin hexapeptide fragment|
From 62.00€ *
Item number: Cay34053-1
Plitidepsin is a depsipeptide that was originally isolated from Aplidium albicans and has diverse biological activities. It binds to the alpha subunit isoform eEF1A2 of eukaryotic elongation factor 1 (eEF1, Kd = 79 nM) and inhibits the proliferation of NCI H460 non-small cell lung cancer (NSCLC) and HGC-27 gastric...
|Keywords:||Aplidin, Dehydrodidemnin B, N-[1-(1,2-dioxopropyl)-L-prolyl]-didemnin A|
|Application:||Bioactive depsipeptide, Antineoplastic|
From 237.00€ *
Item number: Cay34430-1
Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception. It is an agonist of neuromedin-U receptor 1 (NMUR1, EC50 = 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50...
|Application:||Peptide NMUR agonist|
From 123.00€ *
Item number: Cay34543-10
H-Arg-Gly-Asp-Cys-OH is a tetrapeptide that contains the arginine-glycine-aspartate (RGD) motif, a sequence that acts as a recognition site for various adhesion proteins. It inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets with IC50 values of 320 and 35 µM, respectively....
From 62.00€ *
Item number: Cay34624-1
Enterostatin is an endogenous pentapeptide fragment involved in the regulation of food intake. It is released from its precursor protein, procolipase, during digestion and acts in the peripheral and central nervous systems to reduce food, especially fat, intake through the vagus nerve in the periphery and...
|Keywords:||APGPR, L-alanyl-L-prolylglycyl-L-prolyl-L-arginine, trifluoroacetate salt|
|Application:||Food intake regulating pentapeptide|
From 32.00€ *
Item number: Cay34041-10
Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH). It binds to the GnRH receptor (GnRHR) with a Ki value of 0.1 nM. Deslorelin decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs when administered via...
|Keywords:||D-Trp6-Pro9-des-Gly10-GnRH ethylamide, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt,...|
|Application:||GnRH peptide agonist|
From 112.00€ *