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Peptides

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Z-LRGG-AMC (trifluoroacetate salt)
Z-LRGG-AMC (trifluoroacetate salt)

Item number: Cay26641-50

Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T. Upon enzymatic cleavage by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify isopeptidase T activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Keywords: Z-Leu-Arg-Gly-Gly-7-amino-4-methylcoumarin, Z-Leu-Arg-Gly-Gly-AMC,...
Application: Fluorogenic isopeptidase T substrate
CAS 167698-68-2
MW: 692.8 D
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Hexapeptide-11 (acetate)
Hexapeptide-11 (acetate)

Item number: Cay27155-50

Hexapeptide-11 is a synthetic hexapeptide. Hexapeptide-11 (5% v/v) increases the expression of the antioxidant genes Nrf2, Keap1, NQO1, and TXNRD1 and decreases hydrogen peroxide-induced senescence of IMR-90 human lung fibroblasts in vitro. Hexapeptide-11 (5% v/v) increases the activity of matrix metalloproteinase-2...
Keywords: FVAPFP, Phe-Val-Ala-Pro-Phe-Pro, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline, acetic acid
Application: Antioxidant gene expression enchancer
MW: 676.8 D
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Myristoyl Hexapeptide-16 (acetate)
Myristoyl Hexapeptide-16 (acetate)

Item number: Cay27549-500

Myristoyl hexapeptide-16 is a myristoylated form of the hexapeptide Leu-Lys-Lys-Ala-Leu-Lys. An acid form of myristoyl hexapeptide-16 is active against E. coli, P. aeruginosa, S. aureus, and methicillin-resistant S. aureus (MRSA, MICs = =100 ppm for all).
Keywords: Myr-Leu-Lys-Lys-Ala-Leu-Lys, Myr-LKKALK, N-(1-oxotetradecyl)-L-leucyl-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-lysine, acetate
Application: Eyelash enhancer
MW: 910.3 D
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Palmitoyl Tripeptide-38 (acetate)
Palmitoyl Tripeptide-38 (acetate)

Item number: Cay27564-500

Palmitoyl tripeptide-38 is a palmitoylated form of the tripeptide Lys-Met(O2)-Lys-OH. It increases the levels of collagen I, collagen II, fibronectin, and hyaluronic acid by 187, 97, 109, and 55%, respectively, produced by isolated human dermal fibroblasts when used at a concentration of 6 ppm.
Keywords: Pal-KMO2K-OH, Pal-Lys-Met(O2)-Lys-OH, ((S)-2-((S)-6-amino-2-palmitamidohexanamido)-4-(methylsulfonyl)butanoyl)-L-lysine,...
Application: Matrikine-mimetic compound
MW: 67.6 D
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N-(p-Tosyl)-GPR-pNA (acetate)
N-(p-Tosyl)-GPR-pNA (acetate)

Item number: Cay27568-50

N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin. Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.
Keywords: N-(p-Tosyl)-Gly-Pro-Arg-p-Nitroanilide, Tos-Gly-Pro-Arg-pNA,...
Application: Photometric thrombin substrate
CAS 86890-95-1
MW: 662.7 D
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Z-D-Arg-Gly-Arg-pNA (hydrochloride)
Z-D-Arg-Gly-Arg-pNA (hydrochloride)

Item number: Cay27583-5

Z-D-Arg-Gly-Arg-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Arg-Gly-Arg (RGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.
Keywords: Benzyl-D-Arg-Gly-Arg-pNA, Benzyl-D-Arg-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate, S-2765,...
Application: Photometric Factor Xa substrate
CAS 113711-77-6
MW: 714.6 D
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D-Pro-Phe-Arg-pNA (hydrochloride)
D-Pro-Phe-Arg-pNA (hydrochloride)

Item number: Cay27569-50

D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.
Keywords: D-Pro-Phe-Arg-p-nitroaniline, pFR-pNA, Plasma Kallikrein Chromogenic Substrate,...
Application: Photometric plasma kallikrein substrate
CAS 62354-56-7
MW: 611.5 D
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MeO-Suc-RPY-pNA (hydrochloride)
MeO-Suc-RPY-pNA (hydrochloride)

Item number: Cay27706-5

MeO-Suc-RPY-pNA is a colorimetric substrate for serine proteases, including trypsin, chymotrypsin, kallikrein-related peptidase 7 (KLK7), and kallikrein-related peptidase 3/prostate-specific antigen. Serine proteases preferentially bind to and cleave the Arg-Pro-Tyr (RPY) peptide sequence to release p-nitroanilide...
Keywords: Methoxy-Succinyl-Arg-Pro-Tyr-pNA, Methoxy-Succinyl-Arg-Pro-Tyr-p-nitroanilide, S 2586, Serine Protease Chromogenic...
Application: Photometric serine protease substrate
MW: 668.7 D
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Bz-Nle-KRR-AMC (hydrochloride)
Bz-Nle-KRR-AMC (hydrochloride)

Item number: Cay27710-5

Bz-Nle-KRR-AMC is a fluorogenic peptide substrate for yellow fever virus (YFV) non-structural 3 (NS3) and dengue virus (DV) NS2B/3 serine proteases. Upon enzymatic cleavage by YFV NS3 or DV NS2B/3 serine proteases, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify YFV NS3 or DV...
Keywords: Benzoyl-Nle-Lys-Arg-Arg-7-amino-4-methylcoumarin, Benzoyl-Nle-Lys-Arg-Arg-AMC, Bz-Nle-Lys-Arg-Arg-AMC,...
Application: Fluorogenic YFV NS3 peptide substrate
CAS 863975-32-0
MW: 83.3 D
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Ac-QQQ-AMC (hydrochloride)
Ac-QQQ-AMC (hydrochloride)

Item number: Cay27711-5

Ac-QQQ-AMC is a fluorogenic probe. L-Glutamine tripeptide (QQQ) is a substrate for peptidoglutaminase I and II from the bacterium B. circulans. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Keywords: Ac-Gln-Gln-Gln-7-amino-4-methylcoumarin, Ac-Gln-Gln-Gln-AMC, Ac-L-Gln-L-Gln-L-Gln-AMC,...
Application: Fluorogenic probe, B. circulans peptidoglutaminase I & II substrate
MW: 601.6 D
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GHK-Cu (acetate)
GHK-Cu (acetate)

Item number: Cay28259-50

GHK-Cu is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities. It increases proliferation and the levels of collagen and secreted pro-matrix metalloproteinase-2 (MMP-2) in isolated human fibroblasts when used at a concentration of 1 nM. GHK-Cu (2 mg)...
Keywords: Gly-His-Lys-Cu(II), [glycyl-kappaN-L-histidyl-kappaN,kappaN3-L-lysinato(2-)]-copper, monoacetate
Application: Wound healing, antiinflammatory tripeptide copper(II) ion complex
CAS 300801-03-0
MW: 46.2 D
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Pentagastrin
Pentagastrin

Item number: Cay28546-50

Pentagastrin is a synthetic polypeptide and cholecystokinin-2 (CCK2) receptor agonist. It binds selectively to CCK2 receptors in guinea pig brain over CCK1 receptors in rat pancreas (IC50s = 11 and 1,100 nM, respectively). Pentagastrin increases calcium influx and polyphosphoinositide turnover in rat GH3 pituitary...
Keywords: AY 6608, NSC 367746,...
Application: Cholecystokinin-2 receptor agonist
CAS 5534-95-2
MW: 767.9 D
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