Peptides

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Ac-IETD-AFC
Ac-IETD-AFC

Item number: ABD-13410

A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.
Application: Caspase-8 substrate
CAS 211990-57-7
211.00€
Review
MOTS-c (human)
MOTS-c (human)

Item number: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in...
Keywords: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA, Mitochondrial Open Reading Frame of the 12S...
Application: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
From 165.00€
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Z-AEVD-FMK
Z-AEVD-FMK

Item number: Cay14987-500

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.
Keywords: Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone,...
Application: Irreversible caspase-10 inhibitor
CAS 1135688-47-9
MW: 610.6 D
From 69.00€
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Ac-LETD-AFC
Ac-LETD-AFC

Item number: Cay14991-5

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Keywords: Caspase-8 Substrate (Fluorogenic), N-Acetyl-Leu-Glu-Thr-Asp-7-amido-4-Trifluoromethylcoumarin,...
Application: Fluorogenic Caspase-8 substrate
CAS 210345-02-1
MW: 729.7 D
From 78.00€
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AAF-CMK (trifluoroacetate salt)
AAF-CMK (trifluoroacetate salt)

Item number: Cay14461-5

Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome....
Keywords: N-Ala-Ala-Phe-CMK, Tripeptidyl Peptidase Inhibitor II,...
Application: TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor
CAS 184901-82-4
MW: 453.8 D
From 62.00€
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Iberiotoxin
Iberiotoxin

Item number: Cay14608-100

Iberiotoxin, a peptide purified from venom of the scorpion B. tamulus, is a selective blocker of large-conductance calcium ion-activated potassium ion channels (BKCa). In single channel recordings, iberiotoxin can reversibly block outward currents mediated by BKCa in excised membrane patches from bovine aortic...
Keywords: 4-L-aspartic acid-6-L-aspartic acid-8-L-serine-9-L-valine-18-L-lysine-19-L-aspartic...
Application: BKCa blocker
CAS 129203-60-7
MW: 4230.9 D
249.00€
Review
alpha-Bungarotoxin
alpha-Bungarotoxin

Item number: Cay16385-1

alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
Keywords: alpha-Bgt, alpha-BTX, alpha-bungarotoxin
Application: Irreversible nicotinic acetylcholine receptor blocker
CAS 11032-79-4
MW: 7984.2 D
187.00€
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Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp

Item number: Cay16467-1

Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Enzymatic peptide hydrolysis disrupts the Abz:EDDnp donor-acceptor pair allowing fluorescence measurement of Abz (ex = 320 nm, em = 420 nm).
Keywords: N-(2-aminobenzoyl)-L-alanyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-arginyl-L-arginyl-N1-[2-[...
Application: Neutrophil elastase substrate
CAS 824405-61-0
MW: 1456.6 D
249.00€
Review
Apamin
Apamin

Item number: Cay17082-500

Apamin is an 18 amino acid peptide toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3 (IC50 values are 0.06-0.4, 1-12, and 1-13 nM, respectively). It is ineffective against SK4 at 1 µM. Apamin is used to elucidate...
Keywords: Ro 23-6721, CNCKAPETALCARRCQQH (Modifications: Disulfide bridge between 1 - 11, 3 - 15, His-18 = C-terminal amide)
Application: Bee venom toxin, KCa2 blocker
CAS 24345-16-2
MW: 2027.3 D
157.00€
Review
A-54556B
A-54556B

Item number: Cay17090-500

A-54556B is a natural acyldepsipeptide (ADEP) antibiotic isolated from the fermentation broth of S. hawaiiensis. Like the closely related ADEP, A-54556A (Cay-15305), A-54556B is effective against Gram-positive bacteria, including penicillin-resistant S. aureus. A-54556B is also effective against many strains of...
Keywords: A-54556 Factor B, (6->2)-lactone...
Application: Gram-positive bacterial antibiotic
CAS 1629166-56-8
MW: 704.8 D
From 325.00€
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Enopeptin A
Enopeptin A

Item number: Cay17092-500

Enopeptin A, originally isolated from a culture broth of Streptomyces sp. RK-1051, is a depsipeptide antibiotic that contains two unusual amino acids (N-methylalanine and 4-methylproline) and features a pentaenone side chain. It is effective against Gram-positive bacteria, including methicillin-resistant S. aureus...
Keywords: BRN 537924, NSC 657143,...
Application: Gram-positive bacterial antibiotic
CAS 139601-96-0
MW: 896 D
From 374.00€
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Micrococcin P1
Micrococcin P1

Item number: Cay17093-500

Micrococcin P1 is a macrocyclic peptide antibiotic that functions as an acceptor-site-specific inhibitor of ribosomal protein synthesis, effectively preventing the growth of Gram-positive bacteria without affecting that of Gram-negative bacteria.
Keywords: 2'-[(11S,14Z,21S,28S)-14-ethylidene-9,10,11,12,13,14,20,21,27,28-decahydro-28-[(1R)-1-hydroxyethyl]-11-[(1R)-1-hydroxyethy...
Application: Gram-positive bacterial antibiotic
CAS 67401-56-3
MW: 1144.4 D
From 394.00€
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