Peptides

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Ac-DEVD-AFC
Ac-DEVD-AFC

Item number: ABD-13401

A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Application: Caspase-3 substrate
CAS 201608-14-2
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Ac-DEVD-AMC
Ac-DEVD-AMC

Item number: ABD-13402

A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Application: Caspase-3 substrate
CAS 169332-61-0
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(Z-DEVD)2-R110
(Z-DEVD)2-R110

Item number: ABD-13430

Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Application: Caspase-3 substrate, Caspase-7 substrate
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(Ac-PAL)2R110
(Ac-PAL)2R110

Item number: ABD-13467

The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Application: Protease substrate
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3,3',5'-Triiodo-L-thyronine
3,3',5'-Triiodo-L-thyronine

Item number: Cay17598-50

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Keywords: 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine
Application: TR Delta alpha1 activator
CAS 5817-39-0
MW: 651 D
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Angiotensin II (human)
Angiotensin II (human)

Item number: Cay17150-25

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Keywords: 5-L-isoleucine-angiotensin II
Application: Peptide hormone
CAS 4474-91-3
MW: 1046.2 D
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Eledoisin-related Peptide
Eledoisin-related Peptide

Item number: Cay33115-1

Eledoisin-related peptide is a hexapeptide fragment of eledoisin (Cay-28810), an undecapeptide tachykinin neuropeptide and neurokinin (NK) receptor agonist. It induces contractions in isolated guinea pig ileum, as well as alpha-amylase release from rat parotid gland slices, in a concentration-dependent manner....
Keywords: Eledoisin Hexapeptide, Eledoisin RP, KFIGLM-NH2, Lys-Phe-Ile-Gly-Leu-Met-NH2,...
Application: Eledoisin hexapeptide fragment
CAS 2990-43-4
MW: 706.9 D
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Plitidepsin
Plitidepsin

Item number: Cay34053-1

Plitidepsin is a depsipeptide that was originally isolated from Aplidium albicans and has diverse biological activities. It binds to the alpha subunit isoform eEF1A2 of eukaryotic elongation factor 1 (eEF1, Kd = 79 nM) and inhibits the proliferation of NCI H460 non-small cell lung cancer (NSCLC) and HGC-27 gastric...
Keywords: Aplidin, Dehydrodidemnin B, N-[1-(1,2-dioxopropyl)-L-prolyl]-didemnin A
Application: Bioactive depsipeptide, Antineoplastic
CAS 137219-37-5
MW: 1110.3 D
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Neuromedin U-23 (rat) (trifluoroacetate salt)
Neuromedin U-23 (rat) (trifluoroacetate salt)

Item number: Cay34430-1

Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception. It is an agonist of neuromedin-U receptor 1 (NMUR1, EC50 = 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50...
Keywords: NMU-23,...
Application: Peptide NMUR agonist
MW: 2643 D
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H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)
H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)

Item number: Cay34543-10

H-Arg-Gly-Asp-Cys-OH is a tetrapeptide that contains the arginine-glycine-aspartate (RGD) motif, a sequence that acts as a recognition site for various adhesion proteins. It inhibits the binding of fibrinogen to endothelial cells and ADP-stimulated platelets with IC50 values of 320 and 35 µM, respectively....
Keywords: H-RGDC-OH,...
Application: RGD-containing tetrapeptide
MW: 449.5 D
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Enterostatin (human, mouse, rat) (trifluoroacetate salt)
Enterostatin (human, mouse, rat) (trifluoroacetate salt)

Item number: Cay34624-1

Enterostatin is an endogenous pentapeptide fragment involved in the regulation of food intake. It is released from its precursor protein, procolipase, during digestion and acts in the peripheral and central nervous systems to reduce food, especially fat, intake through the vagus nerve in the periphery and...
Keywords: APGPR, L-alanyl-L-prolylglycyl-L-prolyl-L-arginine, trifluoroacetate salt
Application: Food intake regulating pentapeptide
MW: 496.6 D
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Deslorelin (acetate)
Deslorelin (acetate)

Item number: Cay34041-10

Deslorelin is a peptide agonist of gonadotropin-releasing hormone (GnRH). It binds to the GnRH receptor (GnRHR) with a Ki value of 0.1 nM. Deslorelin decreases testicular volume, semen volume, sperm motility, and total sperm count, as well as increases the percentage of abnormal sperm, in dogs when administered via...
Keywords: D-Trp6-Pro9-des-Gly10-GnRH ethylamide, pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-NHEt,...
Application: GnRH peptide agonist
CAS 1642579-30-3
MW: 1282.5 D
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