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Malformin C Item number: Cay21613-1
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
| Keywords: | Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide |
| Application: | Antibacterial |
| CAS | 59926-78-2 |
| MW: | 529.7 D |
From 232.00€ *
alpha-Bungarotoxin Item number: Cay16385-1
alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
| Keywords: | alpha-Bgt, alpha-BTX, alpha-bungarotoxin |
| Application: | Irreversible nicotinic acetylcholine receptor blocker |
| CAS | 11032-79-4 |
| MW: | 7984.2 D |
187.00€ *
Pepstatin Item number: LKT-P1761.25
An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
| Keywords: | Pepstatin A |
| Application: | Aspartyl Protease inhibitor |
| CAS | 26305-03-3 |
| MW: | 685,89 D |
From 91.00€ *
Ac-DEVD-CHO Item number: ABD-13403
A reversible inhibitor of IL-1 converting enzyme (ICE), inhibits poly(ADP-ribose) polymerase cleavage by apopain (caspase 3).
| Application: | Caspase-3 (ICE) inhibitor |
| CAS | 169332-60-9 |
112.00€ *
Ac-DEVD-pNA Item number: ABD-13405
A colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Application: | Caspase-3 substrate |
| CAS | 189950-66-1 |
112.00€ *
Ac-DEVD-AFC Item number: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Application: | Caspase-3 substrate |
| CAS | 201608-14-2 |
112.00€ *
Ac-IETD-AFC Item number: ABD-13410
A fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety.
| Application: | Caspase-8 substrate |
| CAS | 211990-57-7 |
230.00€ *
(Z-DEVD)2-R110 Item number: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Application: | Caspase-3 substrate, Caspase-7 substrate |
112.00€ *
(BOC-VPR)2R110 Item number: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Application: | Fluorogenic alpha-thrombin substrate |
112.00€ *
(Ac-KQL)2R110 Item number: ABD-13465
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Application: | Protease substrate |
112.00€ *
(Z-LLE)2R110 Item number: ABD-13466
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Application: | Protease substrate |
112.00€ *