Peptides

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MOTS-c (human)
MOTS-c (human)

Item number: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in...
Keywords: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA, Mitochondrial Open Reading Frame of the 12S...
Application: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
From 165.00€
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Z-AEVD-FMK
Z-AEVD-FMK

Item number: Cay14987-500

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.
Keywords: Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone,...
Application: Irreversible caspase-10 inhibitor
CAS 1135688-47-9
MW: 610.6 D
From 69.00€
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Ac-LETD-AFC
Ac-LETD-AFC

Item number: Cay14991-5

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Keywords: Caspase-8 Substrate (Fluorogenic), N-Acetyl-Leu-Glu-Thr-Asp-7-amido-4-Trifluoromethylcoumarin,...
Application: Fluorogenic Caspase-8 substrate
CAS 210345-02-1
MW: 729.7 D
From 78.00€
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PAR2 (1-6) (mouse, rat)
PAR2 (1-6) (mouse, rat)

Item number: Cay27125-5

PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces...
Keywords: SLIGRL, L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucine
Application: Synthetic peptide PAR2 agonist
CAS 164081-25-8
MW: 657.8 D
From 44.00€
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PAR4 (1-6) (human)
PAR4 (1-6) (human)

Item number: Cay27126-50

PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4R47A when used at a concentration of 500 µM. PAR4...
Keywords: GYPGQV, glycyl-L-tyrosyl-L-prolylglycyl-L-glutaminyl-L-valine
Application: Synthetic peptide PAR4 agonist
CAS 225779-44-2
MW: 619.7 D
From 162.00€
Review
PAR3 (1-6) (human)
PAR3 (1-6) (human)

Item number: Cay27129-500

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not...
Keywords: TFRGAP, L-threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-L-proline
Application: Synthetic peptide PAR1 agonist
CAS 320347-28-2
MW: 647.7 D
From 69.00€
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Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-3

Item number: Cay27151-50

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 µM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin...
Keywords: N2-acetyl-L-lysylglycyl-L-histidyl-L-lysinamide
Application: Biomimetic peptide
CAS 827306-88-7
MW: 509.6 D
From 32.00€
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Biotin Tripeptide-1
Biotin Tripeptide-1

Item number: Cay27153-50

Biotin tripeptide-1 is an extracellular matrix (ECM) peptide that has been conjugated to biotin (Cay-22582). It stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo. Biotin tripeptide-1 localizes to the peri-pilial zone of isolated cultured human hair follicles, induces...
Keywords: Biotinoyl Tripeptide-1, Biotinyl-GHK, Biotinyl-Gly-His-Lys,...
Application: Biotinylated extracellular matrix (ECM) peptide
CAS 299157-54-3
MW: 566.7 D
From 32.00€
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GHK
GHK

Item number: Cay27168-5

GHK is a peptide released during extracellular matrix (ECM) protein degradation following tissue injury. It binds to copper to form GHK-Cu, a complex with diverse biological activities, including roles in tissue remodeling and wound healing, hair growth, and suppression of inflammation. GHK (1 µM) increases...
Keywords: Gly-His-Lys, NSC 379527, glycyl-L-histidyl-L-lysine
Application: Tissue injury extracellular matrix (ECM) protein degradation peptide
CAS 49557-75-7
MW: 340.4 D
From 32.00€
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CAP 3
CAP 3

Item number: Cay27505-5

CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 µM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces...
Keywords: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-17-((R)-5-(benzyloxy)-5-oxopentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]p...
Application: Antibacterial cholic acid-peptide conjugate (CAP)
MW: 967.3 D
From 62.00€
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Histone H3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3 (23-34) (human, mouse, rat, bovine)...

Item number: Cay28139-1

Histone H3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. It contains lysine residues at positions 23 and 27 that are subject to methylation and acetylation and have a role in the regulation of gene expression and a serine...
Keywords: KAARKSAPATGG, L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycine,...
Application: Peptide fragment, Methylation / acetylation / phosphorylation studies
MW: 1114.3 D
249.00€
Review
Histone H3K27Ac (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3K27Ac (23-34) (human, mouse, rat, bovine)...

Item number: Cay28140-1

Histone H3K27Ac (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Acetylation of histone H3 at lysine 27 is associated with active gene transcription. H3K27 acetylation and H3K4 monomethylation are enriched near active enhancers...
Keywords: [Lys(Ac)27]-Histone H3 (23-34), Histone H3 (23-34) (Lys27ac), KAAR-K(Ac)-SAPATGG,...
Application: Acetylated peptide fragment
MW: 1156.3 D
144.00€
Review
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