Products from NewEast Biosciences

NewEastBio

NewEast Biosciences, headquartered in King of Prussia, PA, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies and cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.

More information at: www.neweastbio.com

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Anti-Active Rac-GTP, monoclonal
Anti-Active Rac-GTP, monoclonal

Item number: NB-26903

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity...
Keywords: Anti-MIG5, Anti-RAC1, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,...
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active Rab5, monoclonal
Anti-Active Rab5, monoclonal

Item number: NB-26911

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway.
Keywords: Anti-RAB5, Anti-RAB5A, Anti-Ras-related protein Rab-5A
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-G.alpha.i, monoclonal
Anti-G.alpha.i, monoclonal

Item number: NB-26003

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. Galphai represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological...
Keywords: Anti-GNAI1, Anti-Adenylate cyclase-inhibiting G alpha protein, Anti-Guanine nucleotide-binding protein G(i) subunit alpha-1
Application: ELISA, WB, IHC
Reactivity: Vertebrates
323.00€ *
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Anti-Ras (G12D), monoclonal
Anti-Ras (G12D), monoclonal

Item number: NB-26036

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased...
Keywords: Anti-KRAS, Anti-KRAS2
Application: ELISA, WB, IHC, IP
Reactivity: Vertebrates
669.00€ *
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Anti-B-Raf (V600E), monoclonal
Anti-B-Raf (V600E), monoclonal

Item number: NB-26039

Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF...
Keywords: Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,...
Application: ELISA, WB, IHC, IP
669.00€ *
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Anti-IDH2 (R172K)
Anti-IDH2 (R172K)

Item number: NB-26163

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Isocitrate dehydrogenase (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. The isocitrate and isopropylmalate dehydrogenases family has three members, IDH1, IDH2 and IDH3. IDH2 plays a role in intermediary...
Keywords: Anti-IDP, Anti-IDH, Anti-IDH2, Anti-ICD-M, EC=1.1.1.42, Anti-NADP(+)-specific ICDH, Anti-Oxalosuccinate decarboxylase,...
Application: ELISA, WB, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active G.alpha.i, monoclonal
Anti-Active G.alpha.i, monoclonal

Item number: NB-26901

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. G alpha i represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological...
Keywords: Anti-GNAI1, Anti-Adenylate cyclase-inhibiting G alpha protein, Anti-Guanine nucleotide-binding protein G(i) subunit...
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active RhoA, monoclonal
Anti-Active RhoA, monoclonal

Item number: NB-26904

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet...
Keywords: Anti-h12, Anti-RHOA, Anti-ARH12, Anti-Rho cDNA clone 12, Anti-Transforming protein RhoA, Anti-Active RhoA-GTP
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active Cdc42, monoclonal
Anti-Active Cdc42, monoclonal

Item number: NB-26905

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity...
Keywords: Anti-CDC42, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active Ras, monoclonal
Anti-Active Ras, monoclonal

Item number: NB-26909

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the...
Keywords: Anti-KRAS, Anti-KRAS2
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-PIK3CA (H1047R)
Anti-PIK3CA (H1047R)

Item number: NB-21146

Concentration: 0.1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2....
Keywords: Anti-PIK3CA, Anti-p110alpha, Anti-PI3Kalpha, Anti-PI3K-alpha, EC=2.7.11.1, EC=2.7.1.153, Anti-PI3-kinase subunit alpha,...
Application: ELISA, WB, IF, IHC
Reactivity: Vertebrates
669.00€ *
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Anti-Active Rap1, monoclonal
Anti-Active Rap1, monoclonal

Item number: NB-26912

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and...
Keywords: Anti-G-22K, Anti-RAP1A, Anti-KREV1, Anti-C21KG, Anti-Ras-related protein Rap-1A, Anti-Ras-related protein Krev-1,...
Application: IP, IHC
Reactivity: Vertebrates
669.00€ *
Review
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