Products from NewEastBio

NewEastBio

NewEast Biosciences, headquartered in King of Prussia, PA, produces antibodies, proteins and assay kits with a strong focus on G-protein research. You also find mutation-specific antibodies and cAMP and cGMP kits with extraordinary specificity due to the use of monoclonal antibodies.

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Ras (Resistance to audiogenic seizures, Asr), human, recombinant full length, His6-tag [E. coli]
Ras (Resistance to audiogenic seizures, Asr),...

Item number: NB-10110-1

Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is...
Host: E.coli
Reactivity: Human
MW: 21 kD
Format: Lyophilized
507.00€
Review
EGFR protein, L858R
EGFR protein, L858R

Item number: NB-10230

Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or...
Reactivity: Human
426.00€
Review
NFE2L2 Protein
NFE2L2 Protein

Item number: NB-10445

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein D77V mutant
NFE2L2 Protein D77V mutant

Item number: NB-10446

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein R34Q mutant
NFE2L2 Protein R34Q mutant

Item number: NB-10447

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein L30F mutant
NFE2L2 Protein L30F mutant

Item number: NB-10448

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein E79Q mutant
NFE2L2 Protein E79Q mutant

Item number: NB-10449

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein D29G mutant
NFE2L2 Protein D29G mutant

Item number: NB-10451

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
NFE2L2 Protein V32T mutant
NFE2L2 Protein V32T mutant

Item number: NB-10452

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reactivity: Human
469.00€
Review
Anti-Orai1 (Orai1-L2)
Anti-Orai1 (Orai1-L2)

Item number: NB-21002

Concentration: 0.5 mg/ml. Formulation: 50mM NaHCO3-Glycine, 0.15M NaCl, pH7.5. Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed...
Application: ELISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Format: Affinity Purified
296.00€
Review
Anti-Rac1
Anti-Rac1

Item number: NB-21003

Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it...
Application: ELISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Vertebrates
Format: Purified
296.00€
Review
Anti-G.alpha.13
Anti-G.alpha.13

Item number: NB-21005

Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are essential cellular signal transducers. Galpha13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Galpha13 are being explored.
Application: ELISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Vertebrates
Format: Purified
296.00€
Review
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