Products from Chimerigen Laboratories

Chimerigen

Chimerigen manufactures unique immunoglobulin based chimeric fusion proteins and their related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic and applied research.

More information at: www.chimerigen.com

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IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-12022-C050

Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22...
Keywords: Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible...
Application: Bioassays
Reactivity: Mouse
From 292.00€ *
Review
IL-35 (mouse):Fc (human) (rec.)
IL-35 (mouse):Fc (human) (rec.)

Item number: CHI-MF-11135-C025

The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation...
Application: Bioassays
Reactivity: Mouse
From 292.00€ *
Review
IL-35 (human):Fc (human) (rec.)
IL-35 (human):Fc (human) (rec.)

Item number: CHI-HF-21035-C025

The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory...
Application: Bioassays
Reactivity: Human
264.00€ *
Review
Galectin-9 (human):Fc (human) (rec.)
Galectin-9 (human):Fc (human) (rec.)

Item number: CHI-HF-210GAL9-C050

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell...
Application: Bioassays
Reactivity: Human
352.00€ *
Review
Tim-4 (human):Fc (mouse) (rec.)
Tim-4 (human):Fc (mouse) (rec.)

Item number: CHI-HF-211T4-C100

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: TIM4, TIMD4, TIM-4, TIMD-4, T-cell membrane protein 4, T-cell immunoglobulin mucin receptor 4, T-cell immunoglobulin and...
Application: Bioassays
Reactivity: Human
MW: ~80 kD
473.00€ *
Review
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)

Item number: CHI-HF-210PDL1-C100

The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
Keywords: B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Application: Bioassays
Reactivity: Human
385.00€ *
Review
COVID-19 Research
SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.)
SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.)

Item number: CHI-B232003-C100

Accession Number: QHD43416.1. Receptor-binding domain (RBD) of SARS-CoV-2 Spike protein S1 (aa 330-530) is fused to the N-terminus of the Fc region of human IgG1. Biological Activity: Binds to the human ACE2. Endotoxin Content: <0.001EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with...
Keywords: 2019-nCoV Spike Protein S1 (RBD)
Application: Bindig assays
Reactivity: Sars-cov-2
528.00€ *
Review
COVID-19 Research
SARS-CoV-2 Spike Protein S1 (RBD) (rec.) (His)
SARS-CoV-2 Spike Protein S1 (RBD) (rec.) (His)

Item number: CHI-B232004-C100

Accession Number: QHD43416.1. Receptor-binding domain (RBD) of SARS-CoV-2 Spike protein S1 (aa 330-530) is fused at the C-terminus to a His-tag. Biological Activity: Binds to the human ACE2. Endotoxin Content: <0.001EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is...
Keywords: 2019-nCoV Spike Protein S1 (RBD)
Application: Bindig assays
Reactivity: Sars-cov-2
528.00€ *
Review
COVID-19 Research
ACE2 (human):Fc (human) (rec.)
ACE2 (human):Fc (human) (rec.)

Item number: CHI-B232006-C100

Extracellular domain of human ACE2 (aa 1-740) is fused to the N-terminus of the Fc region of human IgG1. Biological Activity: Binds to the Spike protein of the coronavirus SARS-CoV-2. Endotoxin Content: <0.001EU/µg purified protein (LAL test). Angiotensin-converting enzyme 2 (ACE2) is an ectoenzyme...
Keywords: ACE2, EC=3.4.17.23, Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog,...
Application: Bindig assays
Reactivity: Human
572.00€ *
Review
COVID-19 Research
SARS-CoV-2 Nucleocapsid Protein (rec.) (His)
SARS-CoV-2 Nucleocapsid Protein (rec.) (His)

Item number: CHI-B233501-C100

Accession Number: QHD43423.2. SARS-CoV-2 Nucleocapsid protein (aa 1-419) is fused at the N-terminus to a His-tag. Endotoxin Content: <1EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133,...
Keywords: 2019-nCoV N Protein
Reactivity: Sars-cov-2
429.00€ *
Review
IL-22 (human):Fc (human) (rec.) (non-lytic)
IL-22 (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-22022-C050

The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-22 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-22...
Keywords: IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor
Application: Bioassays
Reactivity: Human
From 292.00€ *
Review
IL-37 (aa 46-218) (human) (rec.) (His)
IL-37 (aa 46-218) (human) (rec.) (His)

Item number: CHI-AG-40A-0174-C010

IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor...
Keywords: IL37, IL-1X, IL-1H, IL-37, FIL1Z, IL-1H4, IL-1F7, IL-1RP1, FIL1 zeta, IL-1 zeta, Interleukin-37, Interleukin-23,...
Application: Bioassays
Reactivity: Human
MW: ~20 kD
From 253.00€ *
Review
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