Products from Chimerigen Laboratories

Chimerigen

Chimerigen manufactures unique immunoglobulin based chimeric fusion proteins and their related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic and applied research.

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IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-12022-C050

Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22...
Keywords: Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible...
Application: Bioassays
Reactivity: Mouse
From 292.00€ *
Review
IL-35 (mouse):Fc (human) (rec.)
IL-35 (mouse):Fc (human) (rec.)

Item number: CHI-MF-11135-C025

The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation...
Application: Bioassays
Reactivity: Mouse
From 292.00€ *
Review
Galectin-9 (human):Fc (human) (rec.)
Galectin-9 (human):Fc (human) (rec.)

Item number: CHI-HF-210GAL9-C050

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell...
Application: Bioassays
Reactivity: Human
352.00€ *
Review
IL-35 (human):Fc (human) (rec.)
IL-35 (human):Fc (human) (rec.)

Item number: CHI-HF-21035-C025

The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory...
Application: Bioassays
Reactivity: Human
264.00€ *
Review
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)

Item number: CHI-HF-210PDL1-C100

The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
Keywords: B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Application: Bioassays
Reactivity: Human
385.00€ *
Review
CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)
CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-120B7H3-C100

Recombinant Protein. The extracellular domain of mouse CD276 [B7-H3] (aa 30-248) is fused to the N-terminus of the Fc region of mutant mouse IgG2a. Source/Host: HEK 293 cells. Endotoxin: <0.001EU/µg protein (LAL test, Lonza). Lyophilized from 0.2µm-filtered solution in PBS. CD276 (B7-H3) is a member of the B7/CD28...
Keywords: B7h3, Cd276, CD276, B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule
429.00€ *
Review
IL-22 (human):Fc (human) (rec.) (non-lytic)
IL-22 (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-22022-C050

The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-22 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-22...
Keywords: IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor
Application: Bioassays
Reactivity: Human
From 292.00€ *
Review
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) (non-lytic)
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-220PDL1-C100

The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
Keywords: B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Application: Bioassays
Reactivity: Human
385.00€ *
Review
CD27 (human) (rec.) (His)
CD27 (human) (rec.) (His)

Item number: CHI-HR-200CD27-C050

Human CD27 (aa 21-192) is fused at the C-terminus to a His-tag. CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity...
Keywords: T14, CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor...
Application: Bioassays
Reactivity: Human
330.00€ *
Review
IL-23 (mouse):Fc (human) (rec.)
IL-23 (mouse):Fc (human) (rec.)

Item number: CHI-MF-11123-C050

The mouse IL-23 complex composed of the p40 subunit (aa 23-335) and the p19 subunit (aa 20-196) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. 0 Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19...
Keywords: Interleukin-23, Il12b, IL-12B, CLMF p40, IL-12 subunit p40, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation...
Application: Bioassays
Reactivity: Mouse
374.00€ *
Review
FGF-21 (mouse) (rec.)
FGF-21 (mouse) (rec.)

Item number: CHI-MF-102FGF21-C050

Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity. FGF-21 lacks the heparin-binding domain of most FGF proteins, allowing its secretion. FGF-21 is...
Keywords: Fgf21, FGF-21, Fibroblast growth factor 21
Application: Bioassays
Reactivity: Mouse
MW: ~23 kD
From 204.00€ *
Review
IL-7 (human) (rec.) (His)
IL-7 (human) (rec.) (His)

Item number: CHI-HF-20107-C050

Interleukin-7 (IL-7), is a hematopoietic growth factor and a member of the IL-7/IL-9 family. IL-7 stimulates the proliferation of lymphoid progenitors and is secreted by stromal cells in the bone marrow and thymus. IL-7 is also important for proliferation during certain stages of B cell maturation. IL-7 and the...
Keywords: IL7, IL-7, Interleukin-7, Interleukin-7, Lymphopoietin 1, LP-1
Application: Bioassays
Reactivity: Human
MW: ~27 kD
From 226.00€ *
Review
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