Products from Chimerigen Laboratories

Chimerigen

Chimerigen manufactures unique immunoglobulin based chimeric fusion proteins and their related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic and applied research.

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IL-2 (human) Superkine (Fc) MultiPack
IL-2 (human) Superkine (Fc) MultiPack

Item number: CHI-ZHF-21002S-C010

3 x 10 µg. Triggers far greater antitumor responses than native IL-2 in vivo but with lower toxicity. The extracellular domain of human IL-2 (aa 21-153) (mutant H9 containing the mutations L80F / R81D / L85V / I 86V / I92F) is fused at the C-terminus to the Fc portion of human IgG2. Binds to human and mouse IL-2R....
Keywords: IL-2 Superkine (human):Fc (human) (rec.), Interleukin-2, T Cell Growth Factor, TCGF, Aldesleukin, Super-2
Application: Bioassays
Reactivity: Human
From 330.00€
Review
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CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)
CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-120B7H3-C100

Recombinant Protein. The extracellular domain of mouse CD276 [B7-H3] (aa 30-248) is fused to the N-terminus of the Fc region of mutant mouse IgG2a. Source/Host: HEK 293 cells. Endotoxin: <0.001EU/µg protein (LAL test, Lonza). Lyophilized from 0.2µm-filtered solution in PBS. CD276 (B7-H3) is a member of the B7/CD28...
Keywords: B7h3, Cd276, CD276, B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule
429.00€
Review
CX3CL1, Soluble (human) (rec.)
CX3CL1, Soluble (human) (rec.)

Item number: CHI-AG-40A-0079-C050

CX3CL1 [Fractalkine] is expressed on TNF-alpha and IL-1 activated endothelial cells (ECs) and binds to CX3CR1. CX3CL1 can exist in 2 forms, as membrane-anchored or as a shed 95-kDa glycoprotein. The soluble CX3CL1 has potent chemoattractant activity for T cells and monocytes, and the cell surface bound protein,...
Keywords: Fractalkine, Chemokine (C-X3-C Motif) Ligand 1, Neurotactin, SCYD1, FKN, CX3CL1
Application: Bioassays
Reactivity: Human
MW: ~50 kD
From 187.00€
Review
IL-2 (human) (rec.) (His)
IL-2 (human) (rec.) (His)

Item number: CHI-HF-20102-C050

Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation...
Keywords: IL2, IL-2, TCGF, Aldesleukin, Interleukin-2, T-cell growth factor, Interleukin-2, Aldesleukin
Application: Bioassays
Reactivity: Human
MW: ~19 kD
From 182.00€
Review
EGF (human) (rec.) (His)
EGF (human) (rec.) (His)

Item number: CHI-HF-201EGF-C050

Epidermal growth factor (EGF) is a growth factor and the founding member of the EGF family. All EGF family members are synthesized as type I transmembrane precursor proteins that may contain several EGF domains in the extracellular region. The mature proteins are released from the cell surface by regulated...
Keywords: EGF, Pro-Epidermal Growth Factor, HOMG4, URG
Application: Bioassays
Reactivity: Human
MW: ~10 kD
From 182.00€
Review
CCL24 (human):Fc (human) (rec.)
CCL24 (human):Fc (human) (rec.)

Item number: CHI-HF-210CCL24-C050

CCL24 (eotaxin-2) has been shown to induce chemotaxis of eosinophils, basophils and resting T lymphocytes but not monocytes and activated T lymphocytes. CCL24 is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 interacts with chemokine receptor CCR3 to induce...
Keywords: CCL24, MPIF2, MPIF-2, Eotaxin-2, CK-beta-6, C-C motif chemokine 24, Small-inducible cytokine A24, Eosinophil chemotactic...
Application: Bioassays
Reactivity: Human
From 160.00€
Review
IL-22 (human):Fc (human) (rec.)
IL-22 (human):Fc (human) (rec.)

Item number: CHI-HF-21022-C050

The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T...
Keywords: IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor
Application: Bioassays
Reactivity: Human
From 264.00€
Review
IL-4 (human):Fc (human) (rec.) (non-lytic)
IL-4 (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-22004-C050

The extracellular domain of human IL-4 (aa 25-153) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4 (IL-4)...
Keywords: IL4, IL-4, BSF-1, Pitrakinra, Binetrakin, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1
Application: Bioassays
Reactivity: Human
From 215.00€
Review
IL-22 (human):Fc (human) (rec.) (non-lytic)
IL-22 (human):Fc (human) (rec.) (non-lytic)

Item number: CHI-HF-22022-C050

The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-22 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-22...
Keywords: IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor
Application: Bioassays
Reactivity: Human
From 281.00€
Review
CSF3 (mouse):Fc (mouse) (rec.)
CSF3 (mouse):Fc (mouse) (rec.)

Item number: CHI-MF-110CSF3-C050

G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Other cell types including...
Keywords: Csfg, Csf3, G-CSF, Granulocyte colony-stimulating factor, Granulocyte Colony-stimulating Factor, G-CSF
Application: Bioassays
Reactivity: Mouse
From 182.00€
Review
IL-10 (human) (rec.) (His)
IL-10 (human) (rec.) (His)

Item number: CHI-HF-20110-C050

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an...
Keywords: IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor, Interleukin-10, Cytokine Synthesis Inhibitory...
Application: Bioassays
Reactivity: Human
MW: ~18 kD
From 220.00€
Review
IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-12004-C050

The extracellular domain of mouse IL-4 (aa 21-140) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-4 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-4...
Keywords: Il4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1, Lymphocyte...
Application: Bioassays
Reactivity: Mouse
From 215.00€
Review
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