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Products from Chimerigen Laboratories

Chimerigen

Chimerigen manufactures unique immunoglobulin based chimeric fusion proteins and their related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic and applied research.

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CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)
CD276 [B7-H3] (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-120B7H3-C100

Recombinant Protein. The extracellular domain of mouse CD276 [B7-H3] (aa 30-248) is fused to the N-terminus of the Fc region of mutant mouse IgG2a. Source/Host: HEK 293 cells. Endotoxin: <0.001EU/µg protein (LAL test, Lonza). Lyophilized from 0.2µm-filtered solution in PBS. CD276 (B7-H3) is a member of the B7/CD28...
Keywords: B7h3, Cd276, CD276, B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule
429.00€ *
Review
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)
IL-22 (mouse):Fc (mouse) (rec.) (non-lytic)

Item number: CHI-MF-12022-C050

Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22...
Keywords: Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible...
Application: Bioassays
Reactivity: Mouse
From 281.00€ *
Review
IL-35 (mouse):Fc (human) (rec.)
IL-35 (mouse):Fc (human) (rec.)

Item number: CHI-MF-11135-C025

The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation...
Application: Bioassays
Reactivity: Mouse
From 286.00€ *
Review
Galectin-9 (human):Fc (human) (rec.)
Galectin-9 (human):Fc (human) (rec.)

Item number: CHI-HF-210GAL9-C050

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
Keywords: Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell...
Application: Bioassays
Reactivity: Human
341.00€ *
Review
IL-2 (human) Superkine (Fc) MultiPack
IL-2 (human) Superkine (Fc) MultiPack

Item number: CHI-ZHF-21002S-C010

3 x 10 µg. Triggers far greater antitumor responses than native IL-2 in vivo but with lower toxicity. The extracellular domain of human IL-2 (aa 21-153) (mutant H9 containing the mutations L80F / R81D / L85V / I 86V / I92F) is fused at the C-terminus to the Fc portion of human IgG2. Binds to human and mouse IL-2R....
Keywords: IL-2 Superkine (human):Fc (human) (rec.), Interleukin-2, T Cell Growth Factor, TCGF, Aldesleukin, Super-2
Application: Bioassays
Reactivity: Human
From 330.00€ *
Review
IL-35 (human):Fc (human) (rec.)
IL-35 (human):Fc (human) (rec.)

Item number: CHI-HF-21035-C025

The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
Keywords: Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory...
Application: Bioassays
Reactivity: Human
253.00€ *
Review
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)

Item number: CHI-HF-210PDL1-C100

The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
Keywords: B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1
Application: Bioassays
Reactivity: Human
385.00€ *
Review
GDF15 (human):Fc (mouse) (rec.)
GDF15 (human):Fc (mouse) (rec.)

Item number: CHI-HF-211GDF15-C100

Recombinant protein. The extracellular domain of human GDF15 (aa 197-308) is fused to the N-terminus of the Fc region of mouse IgG2a. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. Growth Differentiation Factor 15 (GDF15) is a divergent member of the TGF-beta...
Keywords: Growth/Differentiation Factor 15, GDF-15, Macrophage Inhibitory Cytokine 1, MIC-1, NSAID-activated Gene 1 Protein, NAG-1,...
473.00€ *
Review
beta-Amyloid 42 (human):Fc (human) (rec.)
beta-Amyloid 42 (human):Fc (human) (rec.)

Item number: CHI-HF-210BA42-C100

Protein. The extracellular domain of human beta-Amyloid 42 (aa 672-713) is fused to the N-terminus of the Fc region of human IgG1. Source: HEK 293 cells. Endotoxin: <0.06EU/µg. Lyophilized from 0.2µm-filtered solution in PBS. Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues...
Keywords: Amyloid-beta Protein 42, Abeta42, beta-APP42
473.00€ *
Review
IL-22 (human):Fc (mouse) (rec.)
IL-22 (human):Fc (mouse) (rec.)

Item number: CHI-HF-21122-C050

Recombinant protein. The extracellular domain of human IL-22 (aa 34-179) is fused to the N-terminus of the Fc region of mouse IgG2a. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible...
Keywords: Interleukin-22, IL-10-related T Cell-derived-inducible Factor
From 281.00€ *
Review
FLT3 Ligand (human):Fc (mouse) (rec.)
FLT3 Ligand (human):Fc (mouse) (rec.)

Item number: CHI-HF-211FLT3L-C050

Recombinant protein. The extracellular domain of human FLT3L (aa 27-184) is fused to the N-terminus of the Fc region of mouse IgG2a. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases...
Keywords: FLT3L, FMS-like Tyrosine Kinase 3 Ligand
407.00€ *
Review
GDF15 (mouse):Fc (human) (rec.)
GDF15 (mouse):Fc (human) (rec.)

Item number: CHI-MF-111GDF15-C100

Recombinant protein. The extracellular domain of mouse GDF15 (aa 189-303) is fused to the N-terminus of the Fc region of human IgG1. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. Growth Differentiation Factor 15 (GDF15) is a divergent member of the TGF-beta...
Keywords: Growth/Differentiation Factor 15, GDF-15, Macrophage Inhibitory Cytokine 1, MIC-1
473.00€ *
Review
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