• Please note that we do not deliver goods between 19.12.2019 and 03.01.2020 due to public holidays. However, we are happy to accept orders for deliveries in 2020 during this period.

Products from Innaxon

Innaxon

Innaxon is a company based at in Tewkesbury, United Kingdom focussing on innate immunity, TLR agonists and small molecule inhibitors for research on innate immunity.

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Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re)...

Item number: IAX-100-003-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
Keywords: Monophosphoryl Lipid A [MPLA] derived from E. coli R515 (Re) LPS (biosynthetic)
Application: TLR4 activator
From 119.00€ *
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G-type iODN (inhibitory ODN) Endotoxin-free (sterile)
G-type iODN (inhibitory ODN) Endotoxin-free (sterile)

Item number: IAX-200-052-M001

Potent sequence of an inhibitory ODN of the poly-G class I targeting TLR9, but without effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
Keywords: Inhibitory ODN (iODN): Class I
Application: TLR9 competitor
MW: 6735 D
From 94.00€ *
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ODN 2138 (Control for ODN 1826) Endotoxin-free (sterile)
ODN 2138 (Control for ODN 1826) Endotoxin-free (sterile)

Item number: IAX-200-201-C100

Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 1826 (Cat. No.: IAX-200-002). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
Application: Negative Control for ODN 1826 (IAX-200-002)
MW: 6383 D
94.00€ *
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Polyinosinic-polycytidylic acid [Poly(I:C)] Endotoxin-free (sterile)
Polyinosinic-polycytidylic acid [Poly(I:C)]...

Item number: IAX-200-021-M005

Activates TLR3, MDA5/Helicard and RIG-I. Optimal working concentration depends upon target receptor accessibility, number, density, as well as cell type, and therefore needs to be determined for each application. Recommended concentration range: in vitro: 0.5-10 µg/ml, in vivo: 5mg/kg.
Keywords: Polyinosinic-polycytidylic acid, potassium salt (poly (I:C))
Application: TLR3, MDA5/Helicard, RIG-I activator
From 108.00€ *
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ODN 1668 (Type B) Endotoxin-free (sterile)
ODN 1668 (Type B) Endotoxin-free (sterile)

Item number: IAX-200-001-M001

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
Keywords: CpG ODN TLR9 Agonist: B Type (species: rodent)
Application: TLR9 activator
MW: 6383 D
From 119.00€ *
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ODN M362 (Type C) Endotoxin-free (sterile)
ODN M362 (Type C) Endotoxin-free (sterile)

Item number: IAX-200-004-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Keywords: CpG ODN TLR9 Agonist: A Type (species: human and rodent)
Application: TLR9 activator
MW: 6644 D
From 119.00€ *
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IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
IAXO-101 (CD14/TLR4 Antagonist) (synthetic)

Item number: IAX-600-001-M001

Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
Keywords: Methyl 6-deoxy-6-N-dimethyl-N-cyclopentylammonium-2,3-di-O-tetradecyl-?-D-glucopyranoside iodide
Application: CD14/TLR4 Antagonist
CAS 1202388-64-4
MW: 810.02 D
From 227.00€ *
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LPS (Universal) from S. abortus equi (S-form) TLRpure Sterile Solution
LPS (Universal) from S. abortus equi (S-form) TLRpure...

Item number: IAX-100-009-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Keywords: Lipopolysaccharide (LPS) from Salmonella abortus equi, S-type (smooth/wild-type) LPS
Application: TLR4 activator
From 90.00€ *
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ODN 1826 (Type B) Endotoxin-free (sterile)
ODN 1826 (Type B) Endotoxin-free (sterile)

Item number: IAX-200-002-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
Keywords: CpG ODN TLR9 Agonist: B Type (species: rodent)
Application: TLR9 activator
Reactivity: Mouse, Rat
MW: 6383 D
From 119.00€ *
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ODN 2006 (Type B) Endotoxin-free (sterile)
ODN 2006 (Type B) Endotoxin-free (sterile)

Item number: IAX-200-006-M001

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
Keywords: CpG ODN TLR9 Agonist: B Type (species: human and rodent)
Application: TLR9 activator
MW: 7720 D
From 119.00€ *
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LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution
LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution

Item number: IAX-100-012-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Keywords: Lipopolysaccharide (LPS) from E. coli O111:B4, S-type (smooth/wild-type) LPS
Application: TLR4 activator
From 173.00€ *
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LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution
LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution

Item number: IAX-100-013-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
Keywords: Lipopolysaccharide (LPS) from E. coli O55:B5, S-type (smooth/wild-type) LPS
Application: TLR4 activator
From 173.00€ *
Review
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