Products from Innaxon
Innaxon is a company based at in Tewkesbury, United Kingdom focussing on innate immunity, TLR agonists and small molecule inhibitors for research on innate immunity.
More information at: innaxon.co.uk
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![Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution](https://www.biomol.com/media/image/9d/92/86/IAX-100-003-M001_200x200.png "Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution")
Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re)... Item number: IAX-100-003-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Keywords: | Monophosphoryl Lipid A [MPLA] derived from E. coli R515 (Re) LPS (biosynthetic) |
| Application: | TLR4 activator |
From 140.00€ *
G-type iODN (inhibitory ODN) Endotoxin-free (sterile) Item number: IAX-200-052-M001
Potent sequence of an inhibitory ODN of the poly-G class I targeting TLR9, but without effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Keywords: | Inhibitory ODN (iODN): Class I |
| Application: | TLR9 competitor |
| MW: | 6735 D |
From 109.00€ *
ODN 2138 (Control for ODN 1826) Endotoxin-free (sterile) Item number: IAX-200-201-C100
Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 1826 (Cat. No.: IAX-200-002). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
| Application: | Negative Control for ODN 1826 (IAX-200-002) |
| MW: | 6383 D |
109.00€ *
![Polyinosinic-polycytidylic acid [Poly(I:C)] Endotoxin-free (sterile)](https://www.biomol.com/media/image/c1/8e/e3/IAX-200-021-M002_200x200.png "Polyinosinic-polycytidylic acid [Poly(I:C)] Endotoxin-free (sterile)")
Polyinosinic-polycytidylic acid [Poly(I:C)]... Item number: IAX-200-021-M005
Activates TLR3, MDA5/Helicard and RIG-I. Optimal working concentration depends upon target receptor accessibility, number, density, as well as cell type, and therefore needs to be determined for each application. Recommended concentration range: in vitro: 0.5-10 µg/ml, in vivo: 5mg/kg.
| Keywords: | Polyinosinic-polycytidylic acid, potassium salt (poly (I:C)) |
| Application: | TLR3, MDA5/Helicard, RIG-I activator |
From 125.00€ *
ODN 1668 (Type B) Endotoxin-free (sterile) Item number: IAX-200-001-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Application: | TLR9 activator |
| MW: | 6383 D |
From 140.00€ *
ODN M362 (Type C) Endotoxin-free (sterile) Item number: IAX-200-004-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
| Keywords: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
| Application: | TLR9 activator |
| MW: | 6644 D |
From 140.00€ *
![Physiological Saline [Sodium Chloride 0.9%] Endotoxin-free (sterile)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Physiological Saline [Sodium Chloride 0.9%] Endotoxin-free (sterile)")
Physiological Saline [Sodium Chloride 0.9%]... Item number: IAX-900-003-3010
Chemical. Use for the dilution of TLRpureTM LPS and solubilisation of endotoxin-free reagents (e.g. ODNs).
| Keywords: | Sodium Chloride 0.9% |
| CAS | 7647-14-5 |
From 30.00€ *
LPS from S. typhimurium (S-form) TLRpure Sterile Solution Item number: IAX-100-011-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from Salmonella typhimurium, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 107.00€ *
IAXO-101 (CD14/TLR4 Antagonist) (synthetic) Item number: IAX-600-001-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Keywords: | Methyl 6-deoxy-6-N-dimethyl-N-cyclopentylammonium-2,3-di-O-tetradecyl-?-D-glucopyranoside iodide |
| Application: | CD14/TLR4 Antagonist |
| CAS | 1202388-64-4 |
| MW: | 810.02 D |
264.00€ *
LPS (Universal) from S. abortus equi (S-form) TLRpure... Item number: IAX-100-009-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from Salmonella abortus equi, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 107.00€ *
ODN 1826 (Type B) Endotoxin-free (sterile) Item number: IAX-200-002-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Application: | TLR9 activator |
| Reactivity: | Mouse, Rat |
| MW: | 6383 D |
From 140.00€ *
ODN 2006 (Type B) Endotoxin-free (sterile) Item number: IAX-200-006-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: human and rodent) |
| Application: | TLR9 activator |
| MW: | 7720 D |
From 140.00€ *