• Please note that we do not deliver goods between 19.12.2019 and 03.01.2020 due to public holidays. However, we are happy to accept orders for deliveries in 2020 during this period.

Products from Indigo Biosciences

Indigo

Indigo Biosciences, Inc. was founded in 2005 in State College, PA by Dr. Jack Vanden Heuvel and Dr. Blake Peterson. It remains a privately held biosciences company offering products and services focused on nuclear receptors, which comprise a major class of therapeutic drug targets. The company’s two founders leveraged their collective expertise’s in nuclear receptor biology, toxicology, medicinal chemistry and molecular biology to establish the core platform technology of the company.

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AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Item number: IB-IB03001-32

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Keywords: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Application: Functional activity screening
Reactivity: Human
From 1,068.00€ *
Review
FXR (mouse) Reporter Assay Kit
FXR (mouse) Reporter Assay Kit

Item number: IB-M00601-32

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of human farnesoid X receptor (NR1H4), a ligand-dependent transcription factor commonly referred to as FXR. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: Bar, Nr1h4, Bile acid receptor, Farnesol receptor HRR-1, RXR-interacting protein 14, Farnesoid X-activated receptor,...
Application: Functional activity screening
Reactivity: Mouse
From 1,068.00€ *
Review
PXR (human) Reporter Assay Kit
PXR (human) Reporter Assay Kit

Item number: IB-IB07001

Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the...
Keywords: SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic...
Application: Functional activity screening
Reactivity: Human
From 1,068.00€ *
Review
RORa (Human) Reporter Assay System
RORa (Human) Reporter Assay System

Item number: IB-IB04011-32

Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid,...
Keywords: RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related...
Application: Functional activity screening
Reactivity: Human
From 1,068.00€ *
Review
MR (human) Reporter Assay Kit
MR (human) Reporter Assay Kit

Item number: IB-IB00502

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
Keywords: MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2
Application: Functional activity screening
Reactivity: Human
2,837.00€ *
Review
PR (human) Reporter Assay Kit
PR (human) Reporter Assay Kit

Item number: IB-IB05002

This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the full-length human progesterone receptor (NR3C3), a ligand-dependent transcription factor commonly referred to as PR. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: PR, PGR, NR3C3, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3
Application: Functional activity screening
Reactivity: Human
2,837.00€ *
Review
PPARgamma (human) Reporter Assay Kit
PPARgamma (human) Reporter Assay Kit

Item number: IB-IB00101-32

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
Keywords: NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma
Application: Functional activity screening
Reactivity: Human
From 1,068.00€ *
Review
ERalpha (human) Reporter Assay Kit
ERalpha (human) Reporter Assay Kit

Item number: IB-IB00401

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Application: Functional activity screening
Reactivity: Human
From 1,068.00€ *
Review
AhR (human) Assay Kit
AhR (human) Assay Kit

Item number: IB-IB06001

INDIGO's Aryl Hydrocarbon Receptor (AhR) Reporter Cells include the luciferase reporter gene functionally linked to an AhR-responsive promoter. Thus, quantifying changes in luciferase expression in the treated reporter cells provides a sensitive surrogate measure of the changes in AhR activity. The principle...
Keywords: Aryl Hydrocarbon Receptor (human) Assay Kit, AHR, AhR, BHLHE76, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E...
Application: Functional activity screening
From 1,068.00€ *
Review
GR (human) Reporter Assay Kit
GR (human) Reporter Assay Kit

Item number: IB-IB00202

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human glucocorticoid receptor (NR3C1), a ligand-dependent transcription factor, commonly referred to as GR. INDIGO's reporter cells include the luciferase...
Keywords: GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Application: Functional activity screening
Reactivity: Human
2,837.00€ *
Review
ERalpha (human) Reporter Assay Kit
ERalpha (human) Reporter Assay Kit

Item number: IB-IB00402

This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 1 (NR3A1), a ligand-dependent transcription factor commonly referred to as ERalpha. INDIGO's reporter cells include the luciferase reporter gene...
Keywords: ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1
Application: Functional activity screening
Reactivity: Human
2,837.00€ *
Review
AR (human) Reporter Assay Kit
AR (human) Reporter Assay Kit

Item number: IB-IB03002

This nuclear receptor assay system utilizes proprietary non-human mammalian cells engineered to provide constitutive, high-level expression of full-length, unmodified human androgen receptor (NR3C4), a ligand-dependent transcription factor commonly referred to as AR. INDIGO's reporter cells include the luciferase...
Keywords: AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Application: Functional activity screening
Reactivity: Human
2,837.00€ *
Review
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