Products from LKT Laboratories
LKT Laboratories, Inc., in St. Paul, Minnesota, is a research and development company focused on the discovery of specialty chemicals for cancer chemoprevention. LKT Labs produces and markets unique chemicals and biochemicals for all types of life science research and supply raw materials for manufacturing and research.
More information at: www.lktlabs.com
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Isoflurane Item number: LKT-I7258.250
Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
| Application: | Anesthetic [inhalation] |
| CAS | 26675-46-7 |
| MW: | 184.49 D |
From 58.00€ *
Carmustine Item number: LKT-C0173.100
Carmustine is an antitumor agent.
| Keywords: | BCNU, bis-chloroethylnitrosourea |
| Application: | Anticancer agent |
| CAS | 154-93-8 |
| MW: | 214,05 D |
From 75.00€ *
Fulvestrant Item number: LKT-F8147.5
A synthetic estrogen receptor antagonist. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines.
| Application: | Estrogen receptor antagonist |
| CAS | 129453-61-8 |
| MW: | 606,77 D |
From 71.00€ *
GSK1120212 Item number: LKT-G7440.5
GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
| Keywords: | Trametinib, JTP-74057 |
| Application: | MEK1/2 inhibitor |
| CAS | 871700-17-3 |
| MW: | 615.39 D |
From 118.00€ *
Harringtonin Item number: LKT-H0169.10
An alkaloid isolated from Cephalotaxus harringtonia, and an antitumor agent.
| Keywords: | Cephalotaxine |
| Application: | Anticancer agent |
| CAS | 26833-85-2 |
| MW: | 531,6 D |
From 182.00€ *
Methysticin Item number: LKT-M1679.10
One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property.
| Application: | Metabolic studies |
| CAS | 495-85-2 |
| MW: | 274,27 D |
From 280.00€ *
MG132 Item number: LKT-M2400.5
MG-132 is a proteasome inhibitor that exhibits anti-fibrotic and anti-osteoarthritic activities. In renal interstitial fibroblasts, MG-132 inhibits proliferation and induces apoptosis by activating p53, p21, caspase 3, and Bax. MG-132 also inhibits skeletal muscle atrophy in animal models of chronic obstructive...
| Keywords: | MG-132 |
| Application: | Proteasome inhibitor |
| CAS | 133407-82-6 |
| MW: | 475.62 D |
From 136.00€ *
Pepstatin Item number: LKT-P1761.25
An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
| Keywords: | Pepstatin A |
| Application: | Aspartyl Protease inhibitor |
| CAS | 26305-03-3 |
| MW: | 685,89 D |
From 91.00€ *
Rosuvastatin Calcium Item number: LKT-R5974.25
Statin, HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor.
| Keywords: | (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2- (methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-... |
| Application: | HMGCoA reductase inhibitor |
| CAS | 147098-20-2 |
| MW: | 1001,14 D |
From 169.00€ *
Sorafenib Item number: LKT-S5868.25
c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5 inhibitor, potential HMT inhibitor.
| Keywords: | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide |
| Application: | BRAF / FLT3 / PDGFRB / VEGFR2 / VEGFR3 / c-KIT inhibitor |
| Reactivity: | 56 |
| CAS | 284461-73-0 |
| MW: | 464.82 D |
From 78.00€ *
Celecoxib Item number: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Application: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
From 118.00€ *
Erucin Item number: LKT-E6880.100
An isothiocyanate from cruciferous vegetable. It is effective in apoptosis induction and mitochondrial potiential dissipation.
| Application: | Apoptosis inducer |
| CAS | 4430-36-8 |
| MW: | 161,29 D |
From 183.00€ *