Products from LKT Laboratories
LKT Laboratories, Inc., in St. Paul, Minnesota, is a research and development company focused on the discovery of specialty chemicals for cancer chemoprevention. LKT Labs produces and markets unique chemicals and biochemicals for all types of life science research and supply raw materials for manufacturing and research.
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Harringtonin Item number: LKT-H0169.5
An alkaloid isolated from Cephalotaxus harringtonia, and an antitumor agent.
| Keywords: | Cephalotaxine |
| Application: | Anticancer agent |
| CAS | 26833-85-2 |
| MW: | 531,6 D |
From 182.00€ *
Isoflurane Item number: LKT-I7258.250
Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
| Application: | Anesthetic [inhalation] |
| CAS | 26675-46-7 |
| MW: | 184.49 D |
From 58.00€ *
Carmustine Item number: LKT-C0173.100
Carmustine is an antitumor agent.
| Keywords: | BCNU, bis-chloroethylnitrosourea |
| Application: | Anticancer agent |
| CAS | 154-93-8 |
| MW: | 214,05 D |
From 75.00€ *
Clozapine N-oxide Item number: LKT-C4759.5
Metabolite of clozapine. It is 5-HT2 serotonin receptor antagonist.
| Application: | 5-HT2 serotonin receptor antagonist |
| CAS | 34233-69-7 |
| MW: | 342,82 D |
From 197.00€ *
Fulvestrant Item number: LKT-F8147.5
A synthetic estrogen receptor antagonist. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines.
| Application: | Estrogen receptor antagonist |
| CAS | 129453-61-8 |
| MW: | 606,77 D |
From 71.00€ *
GSK1120212 Item number: LKT-G7440.5
GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
| Keywords: | Trametinib, JTP-74057 |
| Application: | MEK1/2 inhibitor |
| CAS | 871700-17-3 |
| MW: | 615.39 D |
From 118.00€ *
(Z)-4-Hydroxytamoxifen Item number: LKT-H9711.5
An active metabolite of (Z)-tamoxifen which exhibits higher potency as estrogen agonist. It binds to estrogen receptors with 8-fold higher affinity than tamoxifen.
| Application: | Metabolic studies |
| CAS | 68047-06-3 |
| MW: | 387,51 D |
From 165.00€ *
Methysticin Item number: LKT-M1679.10
One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property.
| Application: | Metabolic studies |
| CAS | 495-85-2 |
| MW: | 274,27 D |
From 280.00€ *
MG132 Item number: LKT-M2400.5
MG-132 is a proteasome inhibitor that exhibits anti-fibrotic and anti-osteoarthritic activities. In renal interstitial fibroblasts, MG-132 inhibits proliferation and induces apoptosis by activating p53, p21, caspase 3, and Bax. MG-132 also inhibits skeletal muscle atrophy in animal models of chronic obstructive...
| Keywords: | MG-132 |
| Application: | Proteasome inhibitor |
| CAS | 133407-82-6 |
| MW: | 475.62 D |
From 136.00€ *
Paclitaxel (Semi-synthetic) Item number: LKT-P0093.100
A natural diterpenoid originally isolated from the stem bark of Taxus brevifolia. It promotes the assembly of stable microtubules and inhibits the disassembly process of microtubules to tubulin by calcium ions and by low temperature. Taxol was shown to have activity against cancers, such as P388 and L1210 leukemia,...
| Keywords: | Taxol |
| Application: | Chemopreventive agent |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
From 90.00€ *
Pepstatin Item number: LKT-P1761.25
An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
| Keywords: | Pepstatin A |
| Application: | Aspartyl Protease inhibitor |
| CAS | 26305-03-3 |
| MW: | 685,89 D |
From 91.00€ *
Rosuvastatin Calcium Item number: LKT-R5974.25
Statin, HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor.
| Keywords: | (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2- (methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-... |
| Application: | HMGCoA reductase inhibitor |
| CAS | 147098-20-2 |
| MW: | 1001,14 D |
From 169.00€ *
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