Products from LKT Laboratories

LKT

LKT Laboratories, Inc., in St. Paul, Minnesota, is a research and development company focused on the discovery of specialty chemicals for cancer chemoprevention. LKT Labs produces and markets unique chemicals and biochemicals for all types of life science research and supply raw materials for manufacturing and research.

More information at: www.lktlabs.com

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Isoflurane
Isoflurane

Item number: LKT-I7258.250

Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
Application: Anesthetic [inhalation]
CAS 26675-46-7
MW: 184.49 D
From 58.00€ *
Review
Sorafenib
Sorafenib

Item number: LKT-S5868.25

c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5 inhibitor, potential HMT inhibitor.
Keywords: 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
Application: BRAF / FLT3 / PDGFRB / VEGFR2 / VEGFR3 / c-KIT inhibitor
Reactivity: 56
CAS 284461-73-0
MW: 464.82 D
From 78.00€ *
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Fluoxetine hydrochloride
Fluoxetine hydrochloride

Item number: LKT-F4780.1

A specific serotonin uptake inhibitor. It was found to exert inhibitory or stimulating effects on T-lymphocyte proliferation depending on the concentration.pH value: 5-7 (5% aqueous solution)
Keywords: Fluoxetine HCl
Application: Serotonin uptake inhibitor
CAS 59333-67-4
MW: 345,79 D
From 96.00€ *
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Carmustine
Carmustine

Item number: LKT-C0173.100

Carmustine is an antitumor agent.
Keywords: BCNU, bis-chloroethylnitrosourea
Application: Anticancer agent
CAS 154-93-8
MW: 214,05 D
From 75.00€ *
Review
Fulvestrant
Fulvestrant

Item number: LKT-F8147.5

A synthetic estrogen receptor antagonist. In vitro studies indicate that fulvestrant reversibly inhibits the growth of tamoxifen-resistant, estrogen-sensitive, human breast cancer cell lines.
Application: Estrogen receptor antagonist
CAS 129453-61-8
MW: 606,77 D
From 71.00€ *
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GSK1120212
GSK1120212

Item number: LKT-G7440.5

GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
Keywords: Trametinib, JTP-74057
Application: MEK1/2 inhibitor
CAS 871700-17-3
MW: 615.39 D
From 118.00€ *
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Harringtonin
Harringtonin

Item number: LKT-H0169.5

An alkaloid isolated from Cephalotaxus harringtonia, and an antitumor agent.
Keywords: Cephalotaxine
Application: Anticancer agent
CAS 26833-85-2
MW: 531,6 D
From 182.00€ *
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Methysticin
Methysticin

Item number: LKT-M1679.10

One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property.
Application: Metabolic studies
CAS 495-85-2
MW: 274,27 D
From 280.00€ *
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MG132
MG132

Item number: LKT-M2400.5

MG-132 is a proteasome inhibitor that exhibits anti-fibrotic and anti-osteoarthritic activities. In renal interstitial fibroblasts, MG-132 inhibits proliferation and induces apoptosis by activating p53, p21, caspase 3, and Bax. MG-132 also inhibits skeletal muscle atrophy in animal models of chronic obstructive...
Keywords: MG-132
Application: Proteasome inhibitor
CAS 133407-82-6
MW: 475.62 D
From 136.00€ *
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Pepstatin
Pepstatin

Item number: LKT-P1761.25

An inhibitor of acid proteases isolated from streptomyces. It has been shown to induce contractile effects on rat aorta rings.
Keywords: Pepstatin A
Application: Aspartyl Protease inhibitor
CAS 26305-03-3
MW: 685,89 D
From 91.00€ *
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Rosuvastatin Calcium
Rosuvastatin Calcium

Item number: LKT-R5974.25

Statin, HMG-CoA reductase inhibitor, potential NADPH oxidase and PKC inhibitor.
Keywords: (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2- (methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-...
Application: HMGCoA reductase inhibitor
CAS 147098-20-2
MW: 1001,14 D
From 169.00€ *
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Celecoxib
Celecoxib

Item number: LKT-C1644.1

Celecoxib is a selective COX 2 inhibitor.
Application: COX-2 inhibitor
CAS 169590-42-5
MW: 381,37 D
From 118.00€ *
Review
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