Products from LKT Laboratories
LKT Laboratories, Inc., in St. Paul, Minnesota, is a research and development company focused on the discovery of specialty chemicals for cancer chemoprevention. LKT Labs produces and markets unique chemicals and biochemicals for all types of life science research and supply raw materials for manufacturing and research.
More information at: www.lktlabs.com
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Nitisinone Item number: LKT-N3476.50
Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.
| Keywords: | NTBC, orfadin |
| Application: | 4-hydroxyphenylpyruvate dioxygenase inhibitor |
| CAS | 104206-65-7 |
| MW: | 329.23 D |
From 63.00€ *
Carmustine Item number: LKT-C0173.100
Carmustine is an antitumor agent.
| Keywords: | BCNU, bis-chloroethylnitrosourea |
| Application: | Anticancer agent |
| CAS | 154-93-8 |
| MW: | 214,05 D |
From 75.00€ *
Isoflurane Item number: LKT-I7258.250
Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
| Application: | Anesthetic [inhalation] |
| CAS | 26675-46-7 |
| MW: | 184.49 D |
From 58.00€ *
Paclitaxel (Semi-synthetic) Item number: LKT-P0093.100
A natural diterpenoid originally isolated from the stem bark of Taxus brevifolia. It promotes the assembly of stable microtubules and inhibits the disassembly process of microtubules to tubulin by calcium ions and by low temperature. Taxol was shown to have activity against cancers, such as P388 and L1210 leukemia,...
| Keywords: | Taxol |
| Application: | Chemopreventive agent |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
From 90.00€ *
R,S-Sulforaphane Item number: LKT-S8044.50
R,S-Sulforaphane is a synthetic version of the naturally occurring compound, R-sulforaphane, from Broccoli. It is a racemic mixture of both the R and S isomers. At room temperature, it is a very slightly yellowish viscous liquid. Its isothiocyanate group reacts with protic solvents such as water and ethanol to form...
| Application: | Chemopreventive agent |
| CAS | 4478-93-7 |
| MW: | 177,29 D |
From 186.00€ *
Celecoxib Item number: LKT-C1644.1
Celecoxib is a selective COX 2 inhibitor.
| Application: | COX-2 inhibitor |
| CAS | 169590-42-5 |
| MW: | 381,37 D |
From 118.00€ *
Methysticin Item number: LKT-M1679.10
One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property.
| Application: | Metabolic studies |
| CAS | 495-85-2 |
| MW: | 274,27 D |
From 280.00€ *
Spiramycin Item number: LKT-S6232.5
A macrolide antibiotic. It has been shown to decrease the replication index of humanlymphocytes.
| Keywords: | SPM, RP-5337 |
| Application: | Antibiotic, macrolide |
| CAS | 8025-81-8 |
| MW: | 842,05 D |
From 104.00€ *
GSK1120212 Item number: LKT-G7440.5
GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
| Keywords: | Trametinib, JTP-74057 |
| Application: | MEK1/2 inhibitor |
| CAS | 871700-17-3 |
| MW: | 615.39 D |
From 118.00€ *
ASTX660 Item number: LKT-A744789.1
ASTX660 is an inhibitor of apoptosis proteins found to target BIR3 domain of cIAP1/2 and XIAP through a TNFalpha dependent mechanism in melanoma, breast cancer, and lymphoma cell studies. In a breast cancer xenograft model ASTX660 inhibited tumor growth while displaying no significant adverse effects. Treatment of...
| Keywords: | ASTX660, ASTX-660, ASTX 660, Ethanone,... |
| Application: | CIAP / XIAP dual antagonist |
| CAS | 1799328-86-1 |
| MW: | 539.7 D |
From 453.00€ *
Baloxavir Item number: LKT-B011458.1
Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
| Keywords: | Baloxavir acid, 4G86Y4JT3F,... |
| Application: | Antiviral, Cap-dependent endonuclease inhibitor |
| CAS | 1985605-59-1 |
| MW: | 483.5 D |
From 101.00€ *
Baloxavir Marboxil Item number: LKT-B011460.100
Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
| Keywords: | Xofluza, S-033188,... |
| Application: | Antiviral, Cap-dependent endonuclease inhibitor, Prodrug |
| CAS | 1985606-14-1 |
| MW: | 571.6 D |
From 123.00€ *