Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA. A motivated team of highly-skilled individuals develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA Kits. In addition to the antibody and protein facilities, AdipoGen owns also chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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COVID-19 Research
SARS-CoV-2 Inhibitor Screening Kit Item number: AG-48B-0001-KI01
To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
| Keywords: | COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor... |
| Application: | Compound Screening |
| Reactivity: | Human |
715.00€ *
Latrunculin B Item number: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Keywords: | LAT-B, NSC 339663 |
| Application: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
From 99.00€ *
Anti-Jagged-1 (human), clone J1G53-3, FITC conjugated Item number: AG-20A-0049F-C050
Recognizes human Jagged-1. Detects a band of about 180kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is...
| Keywords: | Protein Jagged-1, CD339, JAG1 |
| Application: | FC |
| Reactivity: | Human |
264.00€ *
Anti-Cardif (human), clone Adri-1 Item number: AG-20B-0004-C100
Recognizes human Cardif. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I (retinoic acid-inducible gene I, Ddx58) and MDA5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA and...
| Keywords: | CARD Adapter Inducing Interferon-beta, IPS-1, Interferon-beta Promoter Stimulator Protein 1, MAVS, Mitochondrial Antiviral... |
| Application: | ICC, IHC, IP, WB |
| Reactivity: | Human |
374.00€ *
Anti-FLIP, clone Dave-2 Item number: AG-20B-0005-C100
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian...
| Keywords: | I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1 |
| Application: | IP, WB |
| Reactivity: | Human , Mouse |
429.00€ *
Anti-RIG-I, clone Alme-1 Item number: AG-20B-0009-C100
Recognizes human and mouse RIG-I. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the...
| Keywords: | RIG-1, Retinoic Acid-inducible Gene 1 Protein, DEAD-box Protein 58, Probable ATP-dependent RNA Helicase DDX58 |
| Application: | IHC, IP, WB |
| Reactivity: | Human , Mouse |
451.00€ *
Anti-ZBP1, clone Zippy-1 Item number: AG-20B-0010-C100
Recognizes human and mouse ZBP1. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZBP1 binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen.
| Keywords: | Z-DNA-binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM-1, DNA-dependent Activator of IFN-regulatory... |
| Application: | IP, WB |
| Reactivity: | Human , Mouse |
429.00€ *
Anti-LAG-3 (human), clone 17B4), ATTO 647N conjugated Item number: AG-20B-0012TS-T100
Recognizes human LAG-3. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function, and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely...
| Keywords: | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
| Application: | FC, ICC |
| Reactivity: | Human |
418.00€ *
Anti-NLRP3/NALP3, clone Cryo-2 Item number: AG-20B-0014-C100
Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
| Keywords: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Application: | WB |
| Reactivity: | Human , Mouse |
308.00€ *
Anti-Polyglutamylation Modification, clone GT335 Item number: AG-20B-0020-C100
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
| Keywords: | Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation |
| Application: | ICC, IP, WB |
| Reactivity: | All |
418.00€ *
Anti-TRAIL-R2 (human), clone TR2.21 Item number: AG-20B-0028-C100
Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Keywords: | TRAIL Receptor 2, DR5, KILLER, TNFRSF 10B, CD262 |
| Application: | FC, IHC, WB |
| Reactivity: | Human |
363.00€ *
Anti-Caspase-1 (p20) (mouse), clone Casper-1 Item number: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragement) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
| Keywords: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Application: | WB |
| Reactivity: | Mouse |
407.00€ *