Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

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Carbenicillin, disodium salt
Carbenicillin, disodium salt

Item number: 50195.5

Effective against gram-positive and gram-negative bacteria. It can be used in plant transformation for killing of Agrobacterium after co-cultivation with plant tissue.
Application: Antibiotic
CAS 4800-94-6
MW: 422.40
From 119.00€
Review
Gentamycin sulfate
Gentamycin sulfate

Item number: LKT-G1658.5

Gentamycin sulfate is an antibiotic from fermentation.
Application: Antibiotic
CAS 1405-41-0
MW: 551,73 D
From 68.00€
Review
Ampicillin, sodium salt
Ampicillin, sodium salt

Item number: 01503.5

Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
Application: Antibiotic
CAS 69-52-3
MW: 371.39
From 23.00€
Review
Sulfasalazine
Sulfasalazine

Item number: Cay15025-5

Sulfasalazine is a prodrug form of the anti-inflammatory agent 5-aminosalicylic acid (Cay-70265) that is covalently linked to the antibiotic sulfapyridine by an azo bond. This bond is rapidly cleaved by bacteria in the terminal ileum and colon, releasing the active anti-inflammatory component. Sulfasalazine (0.1-5...
Keywords: Azopyrin, NSC 203730, NSC 667219, 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-benzoic acid
Application: Apoptosis inducer
CAS 599-79-1
MW: 398.4 D
From 44.00€
Review
Tigecycline
Tigecycline

Item number: Cay15026-5

Tigecycline is a broad-spectrum glycylcycline antibiotic that binds to the bacterial 30S ribosome, blocking the entry of transfer RNA, which halts protein synthesis and inhibits bacterial growth. It is active against a panel of 1,924 European clinical bacterial isolates including S. aureus, S. epidermidis, S....
Keywords: FAR 936, Tygacil,...
Application: Antibiotic, Protein synthesis inhibitor
CAS 220620-09-7
MW: 585.7 D
From 94.00€
Review
Kanamycin A (sulfate)
Kanamycin A (sulfate)

Item number: Cay15321-5

Kanamycin A is a broad spectrum antibiotic isolated from a soil streptomyces (S. kanamyceticus). This aminoglycoside alters translation by prokaryotic ribosomes, resulting in bacterial cell death. In molecular biology, kanamycin A is used as a selective agent to isolate transformants that are expressing a kanamycin...
Keywords: Ophtalmokalixan,...
Application: Antibiotic
CAS 25389-94-0
MW: 582.6 D
From 49.00€
Review
Siomycin A
Siomycin A

Item number: Cay15378-500

The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Siomycin A is a peptide thiazole antibiotic, first isolated from S. sioyaensis, that interacts with the 23S rRNA of bacteria. It inhibits FoxM1 (IC50 = ~5 µM), preventing the...
Keywords: NSC 285116,...
Application: FoxM1 expression inhibitor
CAS 12656-09-6
MW: 1648.9 D
387.00€
Review
Bicyclomycin Benzoate
Bicyclomycin Benzoate

Item number: Cay15384-5

Bicyclomycin benzoate is an antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria. It is inactive against Proteus, P. aeruginosa, and Gram-positive bacteria.
Keywords: FR2054, 3'-benzoate bicyclomycin
Application: Antibiotic
CAS 37134-40-0
MW: 406.4 D
From 144.00€
Review
Ikarugamycin
Ikarugamycin

Item number: Cay15386-500

Ikarugamycin is a macrocyclic antibiotic first isolated from Streptomyces sp. that demonstrates potent antiprotozoal activity. It exhibits cytotoxic effects in cancer cell lines, inhibiting cell proliferation (IC50 = 221.3 nM in HL-60 cells) through genotoxicity and by inducing apoptosis and activation of caspases....
Keywords: (2R,3R,7Z,14S,19E)-3-ethyl-2,3,3aS,5aR,5bS,6,10,11,12,13,14,15,20aS,21,21aR,21bR-hexadecahydro-22-hydroxy-2-methyl-14,17-m...
Application: Antibiotic
CAS 36531-78-9
MW: 478.6 D
From 199.00€
Review
Herbimycin A
Herbimycin A

Item number: Cay15504-500

Herbimycin A is a benzoquinone ansamycin antibiotic from Streptomyces. It has herbicidal activity and acts as a cell-permeable inhibitor of non-receptor tyrosine kinases and the heat shock protein Hsp90. Herbimycin A inhibits Bcr-Abl with an IC50 value of 5 µM, a concentration that also effectively blocks Src, Yes,...
Keywords: Antibiotic TAN 420F, NSC 305978, 17-demethoxy-15R-methoxy-11-O-methyl-geldanamycin
Application: Antibiotic, Hsp90 binding
CAS 70563-58-5
MW: 574.7 D
From 382.00€
Review
Moenomycin Complex
Moenomycin Complex

Item number: Cay15506-5

Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.
Keywords: Bambermycin, Flavomycin, Flavophospholipol, Gainpro
Application: Antibiotic, Bacterial peptidoglycan glycosyltransferase inhibitor
CAS 11015-37-5
MW: 1583.6 D
From 124.00€
Review
Erythromycin
Erythromycin

Item number: Cay16486-5

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l)....
Keywords: Ak-Mycin(R), Eryc(R), NSC 55929, Staticin(R), erythromycin
Application: Antibacterial macrolide antibiotic, Protein synthesis inhibitor (23S rRNA of 50S ribosomal subunit)
CAS 114-07-8
MW: 733.9 D
From 44.00€
Review
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