Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

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Ampicillin, sodium salt
Ampicillin, sodium salt

Item number: 01503.25

Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
Application: Antibiotic
CAS 69-52-3
MW: 371.39
From 23.00€ *
Review
Rapamycin
Rapamycin

Item number: Cay13346-1

Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: AY 22989, NSC 226080, Wy 090217,...
Application: MTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
From 37.00€ *
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Hygromycin B
Hygromycin B

Item number: Cay14291-1

Hygromycin B is an antibiotic which is used in molecular and cell biology to select for transformed cells expressing the hygromycin resistance gene. It is an aminoglycoside produced by the bacterium S. hygroscopicus which kills prokaryotic and eukaryotic cells by inhibiting protein synthesis. The hygromycin...
Keywords: O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N3-methyl-D-strep...
Application: Antibiotic
CAS 31282-04-9
MW: 527.5 D
From 75.00€ *
Review
Bafilomycin A1
Bafilomycin A1

Item number: Cay11038-1

Bafilomycin A1 is a fungal metabolite that has been found in Streptomyces and an inhibitor of vacuolar H+-ATPases (V-ATPases, IC50s = 4, 50, and 400 nM for the Z. mays, bovine adrenal medulla, and N. crassa enzymes, respectively). It is greater than 1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and...
Keywords: NSC 381866,...
Application: V-ATPase inhibitor
CAS 88899-55-2
MW: 622.8 D
From 94.00€ *
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Ionomycin (calcium salt)
Ionomycin (calcium salt)

Item number: Cay11932-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura...
Application: Calcium ionophore
CAS 56092-82-1
MW: 747.1 D
From 32.00€ *
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Ionomycin
Ionomycin

Item number: Cay10004974-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 44.00€ *
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Carbenicillin, disodium salt
Carbenicillin, disodium salt

Item number: 50195.5

Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more...
Application: Antibiotic
CAS 4800-94-6
MW: 422.37
From 121.00€ *
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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Item number: Cay10009542-50

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Keywords: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Application: Antibiotic
CAS 13803-65-1
MW: 462.9 D
From 45.00€ *
Review
NEW
Althiomycin
Althiomycin

Item number: Cay32887-1

Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs = 25, 25, and 3.1 µg/ml, respectively). Althiomycin inhibits protein synthesis in E. coli when used at...
Keywords: NSC 102809,...
Application: Thiazole antibiotic
CAS 12656-40-5
MW: 439.5 D
582.00€ *
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NEW
Tylvalosin (tartrate)
Tylvalosin (tartrate)

Item number: Cay33849-1

Tylvalosin is a macrolide antibiotic. It is active against S. aureus, E. coli, and P. multocida (MICs = 2, 128, and 128 µg/ml, respectively). Tylvalosin (5 and 10 µg/ml) reduces LPS-induced production of pro-inflammatory cytokines, prostaglandin E2 (PGE2, Cay-14010), and nitric oxide in RAW 264.7 cells. It reduces...
Keywords: Acetylisovaleryltylosin tartrate, 3-acetate 4B-(3-methylbutanoate)tylosin, 2R,3R-dihydroxybutanedioate
Application: Macrolide antibiotic, Antibacterial (veterinary), Protein biosynthesis inhibitor
CAS 63428-13-7
MW: 1042.3 D
From 62.00€ *
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NEW
Tebipenem (hydrate)
Tebipenem (hydrate)

Item number: Cay33875-1

Tebipenem is a carbenapenem antibiotic. It is active against a panel of clinical isolates from a variety of bacterial species (MIC50s = =0.0039-8 µg/ml), including methicillin-resistant strains of S. aureus and S. epidermidis and penicillin-resistant S. pneumoniae. Tebipenem inhibits beta-lactamase in a...
Keywords: LJC 11,036, SPR859, TBPM,...
Application: Carbenapenem antibiotic, Antibacterial, Cell wall biosynthesis inhibitor
MW: 383.5 D
From 32.00€ *
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Neospiramycin I
Neospiramycin I

Item number: Cay34060-1

Neospiramycin I is a macrolide antibiotic and derivative of spiramycin I. It is active against the macrolide-sensitive KB210, but not the macrolide-resistant KB224, strain of S. aureus (MICs = 3.12 and >100 µg/ml, respectively), as well as B. cereus, B. subtilis, M. luteus, E. coli, and K. pneumoniae (MICs = 1.56,...
Keywords: 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-9-O-[(2R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2...
Application: Macrolide antibiotic
CAS 70253-62-2
MW: 698.9 D
From 62.00€ *
Review
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