Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria, protozoa or fungi or inhibits their proliferation. Due to this antimicrobial function antibiotics are used as therapeutics in case of bacterial infections. In life sciences, antibiotics are often used for selecting clones after transformation of recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively Antibiotics are used as inhibitors to specifically shut down specific targets, like enzymes or receptors of bacteria and cells. Here you’ll find an extensive portfolio of antibiotics from ampicillin to zelkovamycin for use in the selection of resistant bacteria or inhibition of cells.

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Ampicillin, sodium salt
Ampicillin, sodium salt

Item number: 01503.25

Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
Application: Antibiotic
CAS 69-52-3
MW: 371.39
From 23.00€ *
Review
Bafilomycin A1
Bafilomycin A1

Item number: Cay11038-500

Bafilomycin A1 is a fungal metabolite that has been found in Streptomyces and an inhibitor of vacuolar H+-ATPases (V-ATPases, IC50s = 4, 50, and 400 nM for the Z. mays, bovine adrenal medulla, and N. crassa enzymes, respectively). It is greater than 1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and...
Keywords: NSC 381866,...
Application: V-ATPase inhibitor
CAS 88899-55-2
MW: 622.8 D
From 94.00€ *
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Ionomycin
Ionomycin

Item number: Cay10004974-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 44.00€ *
Review
Hygromycin B
Hygromycin B

Item number: Cay14291-1

Hygromycin B is an antibiotic which is used in molecular and cell biology to select for transformed cells expressing the hygromycin resistance gene. It is an aminoglycoside produced by the bacterium S. hygroscopicus which kills prokaryotic and eukaryotic cells by inhibiting protein synthesis. The hygromycin...
Keywords: O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N3-methyl-D-strep...
Application: Antibiotic
CAS 31282-04-9
MW: 527.5 D
From 75.00€ *
Review
Rapamycin
Rapamycin

Item number: Cay13346-1

Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: AY 22989, NSC 226080, Wy 090217,...
Application: MTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
From 37.00€ *
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Carbenicillin, disodium salt
Carbenicillin, disodium salt

Item number: 50195.5

Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more...
Application: Antibiotic
CAS 4800-94-6
MW: 422.37
From 121.00€ *
Review
Ionomycin (calcium salt)
Ionomycin (calcium salt)

Item number: Cay11932-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura...
Application: Calcium ionophore
CAS 56092-82-1
MW: 747.1 D
From 32.00€ *
Review
Rapamycin
Rapamycin

Item number: AG-CN2-0025-M001

Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
Keywords: Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024
Application: MTOR inhibitor, Immunsuppressant, Apoptosis inducer
CAS 53123-88-9
MW: 914,2 D
From 28.00€ *
Review
NEW
Desfuroylceftiofur
Desfuroylceftiofur

Item number: Cay20360-1

Desfuroylceftiofur is an active metabolite of the broad-spectrum cephalosporin antibiotic ceftiofur (Cay-27301). It is formed from ceftiofur by bovine kidney and liver esterases. Desfuroylceftiofur is active against 539 veterinary isolates of Gram-negative bacteria and Gram-positive cocci bacteria (MIC50s = 0.0078-1...
Keywords: (6R,7R)-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oc...
Application: Ceftiofur metabolite
CAS 120882-22-6
MW: 429.5 D
From 162.00€ *
Review
NEW
Tilmicosin-d3
Tilmicosin-d3

Item number: Cay33545-5

Tilmicosin-d3 is intended for use as an internal standard for the quantification of tilmicosin (Cay-18190) by GC- or LC-MS. Tilmicosin is a macrolide antibiotic. It is active against macrolide-susceptible strains of M. haemolytica, P. multocida, and E. coli (MICs = 4, 4, and 128 µM, respectively), as well as a...
Keywords: (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-(methyl(methyl-d3)amino)tetrahydro-2H-pyran...
Application: GC-MS, LC-MS internal standard, Quantification, Macrolide antibiotic
MW: 872.2 D
269.00€ *
Review
NEW
Maduramicin (ammonium salt)
Maduramicin (ammonium salt)

Item number: Cay34270-100

Maduramicin is a polyether ionophore antibiotic that has been found in Nocardia. It selectively binds to potassium, rubidium, sodium, lithium, and cesium ions over divalent cations. Maduramicin is active against Gram-positive bacteria (MICs = 0.9-125 µg/ml) but not Gram-negative bacteria (MICs = >1,000 µg/ml) or...
Keywords: Antibiotic X-14868A, CL 259,971, Maduramycin, Prinicin, maduramicin alpha, monoammonium salt
Application: Polyether ionophore antibiotic, Coccidiostat
CAS 84878-61-5
MW: 934.2 D
From 57.00€ *
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NEW
Faropenem (sodium salt hydrate)
Faropenem (sodium salt hydrate)

Item number: Cay34507-10

Faropenem is a broad-spectrum penem antibiotic. It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract...
Keywords: (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic...
Application: Penem antibiotic, Antibacterial, Cell wall biosynthesis inhibitor
CAS 158365-51-6
MW: 352.3 D
From 82.00€ *
Review
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