Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used... read more »
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Antibiotics

An antibiotic is a chemical substance that kills bacteria and also some protozoa and fungi or that inhibits their proliferation. Due to their manifold, antimicrobial effects, antibiotics are used as therapeutics in case of bacterial infections. In life science research, antibiotics are often used for selecting positive clones after transformation with recombinant DNA. This method uses resistance genes that are part of the transformed DNA. Alternatively, antibiotics are used as inhibitors to specifically shut down certain targets, including enzymes or receptors of bacteria and cells. Here, you will find an extensive portfolio of antibiotics, from ampicillin to zelkovamycin, that you can use as inhibitors or for the selection of resistant bacteria.

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Bafilomycin A1
Bafilomycin A1

Item number: Cay11038-1

Bafilomycin A1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It is an inhibitor of vacuolar H+-ATPases (V-ATPases, Ki = 0.5 nM in N. crassa vacuolar membranes) and is greater than 1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and H+-ATPases. Bafilomycin...
Keywords: NSC 381866,...
Application: V-ATPase inhibitor
CAS 88899-55-2
MW: 622.8 D
From 125.00€ *
Review
Ionomycin (calcium salt)
Ionomycin (calcium salt)

Item number: Cay11932-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura...
Application: Calcium ionophore
CAS 56092-82-1
MW: 747.1 D
From 44.00€ *
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Hygromycin B (hydrate)
Hygromycin B (hydrate)

Item number: Cay14291-1

Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 µg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis. Hygromycin B has commonly been used in molecular and cell biology applications to select for...
Keywords: O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N3-methyl-D-strep...
Application: Antibiotic
MW: 527.5 D
From 100.00€ *
Review
Ionomycin
Ionomycin

Item number: Cay10004974-1

Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 µM. Ionomycin (5 µM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination...
Keywords: (4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'S)-octahydro...
Application: Ca Ionophore
CAS 56092-81-0
MW: 709 D
From 60.00€ *
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Rapamycin
Rapamycin

Item number: Cay13346-1

Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: AY 22989, NSC 226080, Wy 090217,...
Application: mTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
From 50.00€ *
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Carbenicillin, disodium salt
Carbenicillin, disodium salt

Item number: 50195.5

Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more...
Application: Antibiotic
CAS 4800-94-6
MW: 422.37
From 166.00€ *
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Nigericin (sodium salt)
Nigericin (sodium salt)

Item number: Cay11437-5

Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
Keywords: NSC 292567,...
Application: Metabolic studies
CAS 28643-80-3
MW: 747 D
From 77.00€ *
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Ampicillin Solution 50mg/ml (6-[D-(-)-alpha-Aminophenylacetamido]-penicillanic acid)
Ampicillin Solution 50mg/ml...

Item number: A2262.20

Ampicillin Solution, 50mg/ml, is a convenient, ready to use concentrated solution for molecular biology selection applications. It belongs to the group of beta-lactam antibiotics. These antibotics gram-negative bacteria to which E. coli and Salmonella belong. Beta-lactam antibiotic prevent the formation of...
CAS 69-52-3
MW: 403.40 D
From 37.00€ *
Review
Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Item number: Cay10009542-50

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Keywords: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Application: Antibiotic
CAS 13803-65-1
MW: 462.9 D
From 60.00€ *
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Oligomycin A
Oligomycin A

Item number: Cay11342-5

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis...
Keywords: MCH 32,...
Application: Apoptosis inducer
CAS 579-13-5
MW: 791.1 D
From 76.00€ *
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Ampicillin, sodium salt
Ampicillin, sodium salt

Item number: 01503.25

Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
Application: Antibiotic
CAS 69-52-3
MW: 371.39
From 21.00€ *
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Geldanamycin, FITC-labeled
Geldanamycin, FITC-labeled

Item number: BPS-50312

2.5 µmol/L. A novel geldanamycin fluorescent probe optimized for use with BPS's HSP90 kits (linked). May also be used for detection of cell surface HSP90. Supplied as: DMSO solution (2.5 µM). Avoid freeze/thaw cycles. Keep DMSO stock solutions out of contact with air. Protect from light.
Application: HSP90 detection, kit component
CAS 30562-34-6
MW: 1260.5 D
245.00€ *
Review
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