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Bafilomycin A1
Item number: Cay11038-1
Bafilomycin A1 is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It is an inhibitor of vacuolar H+-ATPases (V-ATPases, Ki = 0.5 nM in N. crassa vacuolar membranes) and is greater than 1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and H+-ATPases....
| Keywords: | NSC 381866,... |
| Application: | V-ATPase inhibitor |
| CAS | 88899-55-2 |
| MW: | 622.8 D |
From 153.00€
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Hygromycin B (hydrate)
Item number: Cay14291-1
Hygromycin B is an aminoglycoside antibiotic that has been found in S. hygroscopicus. It is active against E. coli (MIC = 150 µg/ml) and cytotoxic to both prokaryotic and eukaryotic cells via inhibition of protein synthesis. Hygromycin B has commonly been used in molecular and cell biology applications to select for...
| Keywords: | O-6-amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1->2-3)-O-beta-D-talopyranosyl-(1->5)-2-deoxy-N3-methyl-D-strep... |
| Application: | Antibiotic |
| MW: | 527.5 D |
From 135.00€
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Rapamycin
Item number: Cay13346-1
Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
| Keywords: | AY 22989, NSC 226080, Wy 090217,... |
| Application: | mTORC1 blocking |
| CAS | 53123-88-9 |
| MW: | 914.2 D |
From 60.00€
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Ampicillin, sodium salt
Item number: 01503.25
Crystalline, H2O: <2%, It is effective against gram-positive and some gram-negative bacteria, inhibiting cell wall synthesis.
| Application: | Antibiotic |
| CAS | 69-52-3 |
| MW: | 371.39 |
68.00€
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Carbenicillin, disodium salt
Item number: 50195.5
Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes, although they are more...
| Application: | Antibiotic |
| CAS | 4800-94-6 |
| MW: | 422.37 |
From 183.00€
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Nigericin (sodium salt)
Item number: Cay11437-5
Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
| Keywords: | NSC 292567,... |
| Application: | Metabolic studies |
| CAS | 28643-80-3 |
| MW: | 747 D |
From 101.00€
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Anhydrotetracycline (hydrochloride)
Item number: Cay10009542-50
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
| Keywords: | 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,... |
| Application: | Antibiotic |
| CAS | 13803-65-1 |
| MW: | 462.9 D |
From 76.00€
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![Ampicillin Solution 50mg/ml (6-[D-(-)-alpha-Aminophenylacetamido]-penicillanic acid)](https://www.biomol.com/media/image/96/22/bf/A2262-20_200x200.jpg "Ampicillin Solution 50mg/ml (6-[D-(-)-alpha-Aminophenylacetamido]-penicillanic acid)")
Ampicillin Solution 50mg/ml...
Item number: A2262.20
Ampicillin Solution, 50mg/ml, is a convenient, ready to use concentrated solution for molecular biology selection applications. It belongs to the group of beta-lactam antibiotics. These antibotics gram-negative bacteria to which E. coli and Salmonella belong. Beta-lactam antibiotic prevent the formation of...
| CAS | 69-52-3 |
| MW: | 403.40 D |
From 39.00€
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Oligomycin A
Item number: Cay11342-5
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis...
| Keywords: | MCH 32,... |
| Application: | Apoptosis inducer |
| CAS | 579-13-5 |
| MW: | 791.1 D |
From 87.00€
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Bleomycin (sulfate)
Item number: Cay13877-10
Bleomycin is a glycopeptide antitumor antibiotic produced by the bacterium S. verticillus. Its mechanism of action causes single- and double-strand DNA breaks in tumor cells, which interrupts the cell cycle. Bleomycin is thought to achieve this by chelating metal ions, producing a pseudoenzyme that reacts with...
| Keywords: | Blenoxane, bleomycin sulfate (salt) |
| Application: | Apoptosis inducer |
| CAS | 9041-93-4 |
| MW: | 1415.6 D |
From 55.00€
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Geldanamycin, FITC-labeled
Item number: BPS-50312
2.5 µmol/L. A novel geldanamycin fluorescent probe optimized for use with BPS's HSP90 kits (linked). May also be used for detection of cell surface HSP90. Supplied as: DMSO solution (2.5 µM). Avoid freeze/thaw cycles. Keep DMSO stock solutions out of contact with air. Protect from light.
| Application: | HSP90 detection, kit component |
| CAS | 30562-34-6 |
| MW: | 1260.5 D |
303.00€
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Puromycin (hydrochloride)
Item number: Cay13884-100
Puromycin is a derivative of the glomerular epithelial cell toxin puromycin aminonucleoside (Cay-15509) and an inhibitor of protein synthesis that has been found in S. alboniger. Puromycin is structurally similar to the amino acid-bearing end of tRNA, which allows it to enter the ribosome during protein synthesis,...
| Keywords: | CL 13,900, CL 16,536, NSC 3055, PDH, 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,... |
| Application: | Aminonucleosid antibiotic |
| CAS | 58-58-2 |
| MW: | 544.4 D |
From 59.00€
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