PTM-Specific Antibodies

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Anti-phospho-KAP-1 (Ser824)
Anti-phospho-KAP-1 (Ser824)

Item number: A300-767A

Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of...
Keywords: Anti-phospho-KAP1, Anti-phospho-KAP-1, Anti-phospho-TRIM28, Anti-phospho-KRIP-1, Anti-phospho-TIF1-beta, EC=6.3.2.-,...
Application: WB, IP, IHC, ICC, ICC/IF
Reactivity: Human, Mouse
From 131.00€ *
Review
Anti-phospho-RPA32 (Ser4/Ser8)
Anti-phospho-RPA32 (Ser4/Ser8)

Item number: A300-245A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Application: WB, IP, IHC, ICC/IF
Reactivity: Human, Mouse
From 131.00€ *
Review
Anti-Polyglutamylation Modification, clone GT335
Anti-Polyglutamylation Modification, clone GT335

Item number: AG-20B-0020-C100

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Keywords: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Application: ICC, IP, WB
Reactivity: All
418.00€ *
Review
Anti-phospho-RPA32 (Ser33)
Anti-phospho-RPA32 (Ser33)

Item number: A300-246A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Keywords: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Application: WB
Reactivity: Human
From 131.00€ *
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Anti-phospho-VASP (Ser239), clone 16C2
Anti-phospho-VASP (Ser239), clone 16C2

Item number: 0047-100

Does not cross-react with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins.
Keywords: (pS239) Anti-phospho-VASP, Anti-phospho-VASP, Anti-phospho-Vasodilator-stimulated phosphoprotein
Application: WB, ELISA, IP, ICC, FC
Reactivity: Human, Mouse
390.00€ *
Review
Anti-phospho-RNA Polymerase II (Ser2)
Anti-phospho-RNA Polymerase II (Ser2)

Item number: A300-654A

Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together...
Keywords: Anti-phospho-POLR2, Anti-phospho-POLR2A, EC=2.7.7.6, EC=2.7.7.48, Anti-phospho-RNA polymerase II subunit B1,...
Application: WB, IP, IHC
Reactivity: Human, Mouse
From 131.00€ *
Review
+ Free Secondary
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12

Item number: 200-301-400

The antibody detects a single 370kDa protein in crude extracts prepared either from irradiated human foreskin or mouse 3T3L1 fibroblasts. No reactivity is detected against mock-irradiated cell extracts.
Keywords: Anti-phospho-ATM (pS1981), EC=2.7.11.1, Anti-phospho-A-T mutated, Anti-phospho-Serine-protein kinase ATM,...
Application: ELISA, FC, IHC, IFM, WB
Reactivity: Human, Mouse, Rat
From 132.00€ *
Review
Anti-phospho-EGFR (Tyr1068) (human), Rabbit Monoclonal (RM443)
Anti-phospho-EGFR (Tyr1068) (human), Rabbit Monoclonal...

Item number: REV-31-1334-00-R100

Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
Keywords: Anti-phospho-ERBB, EC=2.7.10.1, Anti-phospho-Proto-oncogene c-ErbB-1, Anti-phospho-Epidermal growth factor receptor,...
Application: WB
Reactivity: Human
418.00€ *
Review
Anti-detyrosinated-alpha-Tubulin (human), Rabbit Monoclonal (RM444)
Anti-detyrosinated-alpha-Tubulin (human), Rabbit...

Item number: REV-31-1335-00-R100

Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]
Keywords: Anti-detyrosinated-TUBA2, Anti-detyrosinated-TUBA3C, anti-Detyrosinated alpha-Tubulin (human), Rabbit Monoclonal (RM444),...
Application: WB, ICC
Reactivity: Human
418.00€ *
Review
Anti-gamma-H2AX
Anti-gamma-H2AX

Item number: A300-081A

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Keywords: Anti-H2AX, Anti-H2AFX, Anti-H2a/x, Anti-Histone H2AX, Anti-Histone H2A.X
Application: WB, IHC, ICC/IF
Reactivity: Human, Mouse
From 131.00€ *
Review
+ Free Secondary
Anti-phospho-Histone H2AvD (Ser137)
Anti-phospho-Histone H2AvD (Ser137)

Item number: 600-401-914

Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA...
Keywords: Anti-phospho-H2AvD, Anti-phospho-H2A.Z, Anti-phospho-His2Av, Anti-phospho-CG5499, Anti-phospho-H2A.F/Z,...
Application: ELISA, IHC, WB
Reactivity: Drosophila
506.00€ *
Review
Anti-phospho-CDKN2A (Ser8)
Anti-phospho-CDKN2A (Ser8)

Item number: NSJ-F48749-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase....
Keywords: Anti-phospho-MTS-1, Anti-phospho-CDKN2, Anti-phospho-CDK4I, Anti-phospho-p16-INK4, Anti-phospho-p16INK4A,...
Application: DB, ELISA
Reactivity: Human
From 228.00€ *
Review
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