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Item number: 12136.25
Leupeptin, also known as N-acetyl-L-leucyl-L-leucyl-L-argininal, is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. It is often used during in vitro experiments when a specific enzymatic reaction is being studied. When cells are lysed for these studies, proteases,...
From 83.00€ *
Item number: 50375.1
5-Bromo-3-Indolyl-ß-D-Galactopyranoside (Bluo-Gal) is a substrate for the histochemical localization of ß-galactosidase. Bluo-Gal is an alternative to X-Gal, producing a darker blue color.
Item number: 04010.10
DTT is an unusually strong reducing agent, because once oxidized, it forms a stable six-membered ring with an internal disulfide bond. The reduction usually does not stop at the mixed-disulfide species because the second thiol of DTT has a high propensity to close the ring, forming oxidized DTT and leaving behind a...
From 40.00€ *
Item number: 04943.1
Glycine (abbreviated as Gly or G) is the smallest of the 20 amino acids commonly found in proteins, having a hydrogen substituent as its side-chain. Its codons are GGU, GGC, GGA, GGG of the genetic code. Glycine is often used as a counterion in SDS-PAGE and in buffers for western blotting.
|Application:||Buffer component, Protein stabilization|
From 30.00€ *
Item number: 05684.5
Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments.
|Application:||Inducer of beta-galactosidase|
From 32.00€ *
Item number: 54686.100
DMSO is a polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. DMSO is less toxic than other members of this class, such as dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone, and HMPA. DMSO is also used in PCR to...
From 29.00€ *
Item number: Cay71740-10
Rosiglitazone is a thiazolidinedione agonist of peroxisome proliferator-activated receptor gamma (PPARgamma) that binds to the ligand binding domain (LBD) of PPARgamma with a Kd value of 43 nM. It selectively activates chimeras containing the LBDs of PPARgamma over PPARalpha and PPARdelta in a cell-based reporter...
|Keywords:||BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione|
From 35.00€ *
Item number: 15655.1
MTT, a yellow tetrazole, is reduced to purple formazan in living cells. A solubilization solution (usually either dimethyl sulfoxide, an acidified ethanol solution, or a solution of the detergent sodium dodecyl sulfate in diluted hydrochloric acid) is added to dissolve the insoluble purple formazan product into a...
|Application:||Cell viability assay|
From 28.00€ *
Item number: Cay13122-1
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein...
|Application:||GSK3alpha and GSK3beta inhibitor|
From 32.00€ *
Item number: 16156.100
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the...
|Keywords:||beta-Nicotinamide-adenine-dinucleotide phosphate, reduced Na4-salt|
From 72.00€ *
Item number: Cay18570-1
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
|Keywords:||15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid|
|Application:||Bioactive lipid assays|
From 32.00€ *