Products from Bethyl Laboratories

Bethyl

Bethyl Laboratories is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies to the research market. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations and scholarly searches. Bethyl Labs is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies.

More information at: www.bethyl.com

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Anti-ASH2
Anti-ASH2

Item number: A300-489A

Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone...
Keywords: Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2
Application: WB, IP, IHC, ChIP, ChIP-chip
Reactivity: Human
443.00€ *
Review
Anti-RBM9 (IHC)
Anti-RBM9 (IHC)

Item number: IHC-00199

Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to...
Keywords: Anti-FOX2, Anti-RBFOX2, Anti-Fox-1 homolog B, Anti-RNA-binding protein 9, Anti-RNA-binding motif protein 9, Anti-RNA...
Application: IHC
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-SMARCC2/BAF170 (IHC)
Anti-SMARCC2/BAF170 (IHC)

Item number: IHC-00213

Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters...
Keywords: Anti-BAF170, Anti-SMARCC2, Anti-BRG1-associated factor 170, Anti-SWI/SNF complex 170 kDa subunit, Anti-SWI/SNF complex...
Application: IHC
Reactivity: Human, Mouse
From 125.00€ *
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Anti-MafA (IHC)
Anti-MafA (IHC)

Item number: IHC-00352

Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
Keywords: Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf...
Application: IHC
Reactivity: Mouse
From 125.00€ *
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Anti-Ki-67 (IHC)
Anti-Ki-67 (IHC)

Item number: IHC-00375

Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226)....
Keywords: Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by...
Application: IHC
Reactivity: Mouse
From 125.00€ *
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Anti-phospho-EZH2 (Ser21) (IHC)
Anti-phospho-EZH2 (Ser21) (IHC)

Item number: IHC-00388

Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...
Keywords: Anti-phospho-EZH2, Anti-phospho-KMT6, Anti-phospho-ENX-1, EC=2.1.1.43, Anti-phospho-Enhancer of zeste homolog 2,...
Application: IHC
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-ZEB1 (IHC)
Anti-ZEB1 (IHC)

Item number: IHC-00419

Protein function: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by...
Keywords: Anti-ZEB1, Anti-AREB6, Anti-TCF-8, Anti-Transcription factor 8, Anti-Negative regulator of IL2, Anti-NIL-2-A zinc finger...
Application: IHC
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-BRG1/SMARCA4 (IHC)
Anti-BRG1/SMARCA4 (IHC)

Item number: IHC-00466

Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
Keywords: Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,...
Application: IHC
Reactivity: Human, Mouse
From 125.00€ *
Review
Anti-CASC5 (IHC)
Anti-CASC5 (IHC)

Item number: IHC-00500

Protein function: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may...
Keywords: Anti-CT29, Anti-CASC5, Anti-Blinkin, Anti-AF15q14, Anti-KIAA1570, Anti-Protein CASC5, Anti-Protein D40/AF15q14,...
Application: IHC
Reactivity: Human
From 125.00€ *
Review
Anti-YAP1 (IHC)
Anti-YAP1 (IHC)

Item number: IHC-00665

Protein function: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis...
Keywords: Anti-YAP1, Anti-YAP65, Anti-Protein yorkie homolog, Anti-Yes-associated protein 1, Anti-Transcriptional coactivator YAP1,...
Application: IHC, IHC-IF
Reactivity: Human
From 125.00€ *
Review
Anti-ECS (DDDDK)
Anti-ECS (DDDDK)

Item number: A190-101A

Keywords: Anti-FLAG-Tag
Application: WB, IP, ICC, ELISA
248.00€ *
Review
Anti-c-myc
Anti-c-myc

Item number: A190-104A

Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. [The UniProt Consortium]
Keywords: Anti-MYC, Anti-bHLHe39, Anti-BHLHE39, Anti-Proto-oncogene c-Myc, Anti-Transcription factor p64, Anti-Myc proto-oncogene...
Application: WB, IP, ICC, ELISA
248.00€ *
Review
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