Products from Bethyl Laboratories
Bethyl Laboratories is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies to the research market. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations and scholarly searches. Bethyl Labs is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies.
More information at: www.bethyl.com
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Anti-RbBP5 Item number: A300-109A
Protein function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or...
| Keywords: | Anti-RBQ3, Anti-RBBP5, Anti-RBBP-5, Anti-Retinoblastoma-binding protein 5, Anti-Retinoblastoma-binding protein RBQ-3 |
| Application: | WB, IP, IHC, ICC, ChIP, ChIP-chip |
| Reactivity: | Human |
From 125.00€ *
NEW
Anti-p73 Item number: A300-126A
Protein function: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. [The UniProt Consortium]
| Keywords: | Anti-P73, Anti-TP73, Anti-Tumor protein p73, Anti-p53-related protein, Anti-p53-like transcription factor |
| Application: | WB, IP |
| Reactivity: | Human |
From 125.00€ *
NEW
Anti-HdmX/MDM4 Item number: A300-287A
Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions. [The UniProt Consortium]
| Keywords: | Anti-MDM4, Anti-MDMX, Anti-Protein Mdm4, Anti-Protein Mdmx, Anti-Double minute 4 protein, Anti-p53-binding protein Mdm4,... |
| Application: | WB, IP |
| Reactivity: | Human |
From 125.00€ *
Anti-ASH2 Item number: A300-489A
Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone...
| Keywords: | Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2 |
| Application: | WB, IP, IHC, ChIP, ChIP-chip |
| Reactivity: | Human |
443.00€ *
Anti-BRD4 Item number: A301-985A50
Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
| Keywords: | Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4 |
| Application: | WB, IP, IHC |
| Reactivity: | Human, Mouse |
470.00€ *
NEW
Anti-SMC5 Item number: A300-236A
Protein function: Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere...
| Keywords: | Anti-SMC5, Anti-SMC-5, Anti-hSMC5, Anti-KIAA0594, Anti-SMC protein 5, Anti-Structural maintenance of chromosomes protein 5 |
| Application: | WB, IP |
| Reactivity: | Human, Mouse |
From 125.00€ *
Anti-RBM9 (IHC) Item number: IHC-00199
Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to...
| Keywords: | Anti-FOX2, Anti-RBFOX2, Anti-Fox-1 homolog B, Anti-RNA-binding protein 9, Anti-RNA-binding motif protein 9, Anti-RNA... |
| Application: | IHC |
| Reactivity: | Human, Mouse |
From 125.00€ *
Anti-SMARCC2/BAF170 (IHC) Item number: IHC-00213
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters...
| Keywords: | Anti-BAF170, Anti-SMARCC2, Anti-BRG1-associated factor 170, Anti-SWI/SNF complex 170 kDa subunit, Anti-SWI/SNF complex... |
| Application: | IHC |
| Reactivity: | Human, Mouse |
From 125.00€ *
Anti-MafA (IHC) Item number: IHC-00352
Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
| Keywords: | Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf... |
| Application: | IHC |
| Reactivity: | Mouse |
From 125.00€ *
Anti-Ki-67 (IHC) Item number: IHC-00375
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226)....
| Keywords: | Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by... |
| Application: | IHC |
| Reactivity: | Mouse |
From 125.00€ *
Anti-phospho-EZH2 (Ser21) (IHC) Item number: IHC-00388
Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...
| Keywords: | Anti-phospho-EZH2, Anti-phospho-KMT6, Anti-phospho-ENX-1, EC=2.1.1.43, Anti-phospho-Enhancer of zeste homolog 2,... |
| Application: | IHC |
| Reactivity: | Human, Mouse |
From 125.00€ *
Anti-ZEB1 (IHC) Item number: IHC-00419
Protein function: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by...
| Keywords: | Anti-ZEB1, Anti-AREB6, Anti-TCF-8, Anti-Transcription factor 8, Anti-Negative regulator of IL2, Anti-NIL-2-A zinc finger... |
| Application: | IHC |
| Reactivity: | Human, Mouse |
From 125.00€ *
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