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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1365-0.1 | 100 µg | - |
3 - 11 business days* |
608.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
H-Ras is one of three ubiquitously isoforms of Ras GTPase that operate at the intracellular... more
Product information "Anti-H-Ras Monoclonal Antibody (Clone:H-RAS-03)"
H-Ras is one of three ubiquitously isoforms of Ras GTPase that operate at the intracellular leaflet of the plasma membrane to regulate multiple signal transduction pathways, such as mitogen-activated protein kinase (MAPK) cascade. H Ras is anchored to the plasma membrane by farnesyl and two palmityl residues. GTP loading decreases H-Ras affinity for lipid rafts and allows the protein to target to nonraft microdomains, the primary sites of H-Ras signaling. Sos protein and other guanine nucleotide-exchange factors catalyze dissociation of GDP from Ras. Besides its roles in the plasma membrane, active H-Ras also diffuses through the cytoplasm on nanoparticles termed rasosomes, which is dependent on Ras palmitoylation. Protein function: Involved in the activation of Ras protein signal transduction (PubMed:22821884). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151). [The UniProt Consortium]
Keywords: | Anti-HRAS, Anti-HRAS1, Anti-H-Ras Monoclonal Antibody (Clone:H-RAS-03) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1365 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | H-RAS-03 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein |
Format: | Affinity Purified |
Database Information
KEGG ID : | K02833 | Matching products |
UniProt ID : | P01112 | Matching products |
Gene ID | GeneID 3265 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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