58 products were found matching "K02833"!

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Erastin
Erastin

Item number: Cay17754-1

Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...
Keywords: 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Application: Antitumor agent
CAS 571203-78-6
MW: 547.1 D
From 60.00€ *
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ML-210
ML-210

Item number: Cay23282-1

ML-210 is an inhibitor of glutathione peroxidase 4 (GPX4). It reduces viability of mesenchymal-state KP4 cells, an effect that can be blocked by the arachidonic acid lipoxygenase inhibitors PD 146176 (Cay-10010518) and zileuton (Cay-10006967). It is also selectively lethal to mutant RAS oncogene-expressing cells...
Keywords: DPI10, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-methanone
Application: HRas(G12V)-expressing cell specific cytotoxin
CAS 1360705-96-9
MW: 475.3 D
From 43.00€ *
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Anti-Ras (Q61L), monoclonal
Anti-Ras (Q61L), monoclonal

Item number: NB-26193

Recognizes Ras (Q61L), but not wild type Ras protein from vertebrates. Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras protein is a membrane associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61L mutation...
Keywords: Anti-HRAS, Anti-HRAS1, Anti-KRAS, Anti-KRAS2, Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras...
Application: ELISA, WB, IHC
Host: Mouse
Species reactivity: human
717.00€ *
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Anti-Ras (Q61R), monoclonal
Anti-Ras (Q61R), monoclonal

Item number: NB-26192

Recognizes Ras (Q61R), but not wild type Ras protein from vertebrates. Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras protein is a membrane associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61R mutation...
Keywords: Anti-HRAS, Anti-HRAS1, Anti-KRAS, Anti-KRAS2, Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras...
Application: ELISA, WB, IHC
Host: Mouse
Species reactivity: human
717.00€ *
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Anti-H-RAS
Anti-H-RAS

Item number: NSJ-F41616-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic...
Keywords: Anti-HRAS, Anti-HRAS1, H-RAS Antibody
Application: WB, IF, ELISA
Host: Rabbit
Species reactivity: human, mouse
From 326.00€ *
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Kobe 0065
Kobe 0065

Item number: Cay16261-5

The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
Keywords: N-(3-chloro-4-methylphenyl)-2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-hydrazinecarbothioamide
Application: Ras inhibitor
CAS 436133-68-5
MW: 449.8 D
From 50.00€ *
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Farnesyl Thiosalicylic Acid Amide
Farnesyl Thiosalicylic Acid Amide

Item number: Cay13175-1

Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM,...
Keywords: FTS Amide, Salirasib Amide, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzamide
Application: Ras signaling inhibitor
CAS 1092521-74-8
MW: 357.6 D
From 26.00€ *
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Kobe 2602
Kobe 2602

Item number: Cay16262-10

The Ras family of small GTPases (H-Ras, K-Ras, and N-Ras) function as molecular switches, cycling between a GTP-bound active state and a GDP-bound inactive state, to turn on downstream Raf protein kinases. This initiates complex signaling pathways involved in cell growth, differentiation, and apoptosis. Mutations...
Keywords: 2-[2,6-dinitro-4-(trifluoromethyl)phenyl]-N-(4-fluorophenyl)-hydrazinecarbothioamide
Application: RAS inhibitor
CAS 454453-49-7
MW: 419.3 D
From 43.00€ *
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Anti-H-Ras, clone H-RAS-03
Anti-H-Ras, clone H-RAS-03

Item number: ARG63022.100

Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
Keywords: Anti-HRAS, Anti-HRAS1
Application: WB
Host: Mouse
Species reactivity: human
624.00€ *
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Human H-RAS ELISA Kit
Human H-RAS ELISA Kit

Item number: G-HUFI01189.96

Application: ELISA
Species reactivity: human
641.00€ *
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Anti-HRAS
Anti-HRAS

Item number: NSJ-R31861

0.5mg/ml if reconstituted with 0.2ml sterile DI water. GTPase HRas, also known as transforming protein p21, is an enzyme that in humans is encoded by the HRAS gene. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products...
Keywords: Anti-HRAS, Anti-HRAS1, HRAS Antibody
Application: WB
Host: Rabbit
Species reactivity: human, mouse
755.00€ *
Review
Anti-HRAS
Anti-HRAS

Item number: NSJ-R31862

0.5mg/ml if reconstituted with 0.2ml sterile DI water. GTPase HRas, also known as transforming protein p21, is an enzyme that in humans is encoded by the HRAS gene. This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products...
Keywords: Anti-HRAS, Anti-HRAS1, HRAS Antibody
Application: WB
Host: Rabbit
Species reactivity: human, mouse, rat
755.00€ *
Review
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