Anti-Ah Receptor (Aryl Hydrocarbon Receptor, AHR, Aromatic Hydrocarbon Receptor, BHLHE76, Class E Ba

Aryl hydrocarbon receptor (AHR) is a 96kD ligand-activated transcription factor expressed in all tissues tested. AHR binds planar aromatic hydrocarbons and plays a role in regulating biological responses to them. It activates expression of xenobiotic chemical metabolising enzyme genes such as cytochrome P450. AHR is also involved in cell-cycle regulation and is thought to be involved in tissue maturation. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections. 0.01M sodium citrate buffer, pH 6.0 is recommended. , Optimal dilutions to be determined by the researcher. Positive Control: Respitory epithelium and bronchial smooth muscle, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.