Other Cell-Based Assays

This kit makes use of a cell-permeant inhibitor linked to a green fluorescent label targeted by serine proteases to measure chymotrypsin-like protease activation in whole living cells. Reagent: FAM-Leu-DAP.

This kit makes use of a cell-permeant inhibitor linked to a green fluorescent label targeted by serine proteases to measure chymotrypsin-like protease activation in whole living cells. Reagent: FAM-Leu-DAP.

Cayman's NETosis Imaging Kit provides a simple staining protocol for visualizing the process of NETosis kinetically ex vivo and in vitro. A cell-permeable DNA dye allows visualization of the dynamic changes of the nucleus during the process of NETosis, while a cell-impermeable dye detects the extruded DNA. Combining...

The kit uses a proprietary lysotropic dye that selectively accumulates in lysosomes probably vial the lysosome pH gradient. The dye easily permeates intact live cells, and trapped in lysosomes after it gets into cells. This particular kit is designed to label lysosomes of live cells in orange fluorescence at Ex/Em =...

Our Cell Navigator(TM) fluorescence imaging kits are a set of fluorescence imaging tools for labeling sub-cellular organelles such as membranes, lysosomes, mitochondria, nuclei, etc. The selective labeling of live cell compartments provides a powerful method for studying cellular events in a spatial and temporal...

G protein coupled receptors (GPCR) are one of the largest receptor classes targeted by drug discovery programs. Calcium flux (coupled via Gq pathway) assay is a preferred method in drug discovery for screening GPCR targets. However, over 60% of the known GPCRs signal through adenylyl cyclase activity coupled to...

The Cell Navigator(TM) fluorescence imaging kits are a set of fluorescence imaging tools for labeling sub-cellular organelles such as membranes, lysosomes, mitochondria and nuclei etc. This particular kit is designed to label mitochondria of live cells in orange fluorescence. The cell images can be viewed with the...

This complete kit is designed to label mitochondria of live cells in red fluorescence. The kit uses a proprietary dye that selectively accumulates in mitochondria probably via the mitochondrial membrane potential gradient. The kit uses a proprietary dye that selectively accumulates in mitochondria probably vial the...

Phosphodiesterases (PDEs) play an important role in the dynamic regulation of cAMP and cGMP signaling. PDE4D has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP. Inhibition of PDE4D activity by its inhibitors leads to an elevated intracellular level of cAMP. The PDE4D gene encodes at least 9 different...

The human IDO1 Cell-Based Assay Kit is designed to monitor the activity of exogenously expressed human IDO1 in cultured cells.

The human TDO Cell-Based Assay Kit is designed to monitor the activity of exogenously expressed human TDO in cultured cells.

The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various...