Reporter Assays

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Melanocortin-3 Receptor Reporter Assay Kit
Melanocortin-3 Receptor Reporter Assay Kit

Item number: Cay600180-100

The Melanocortin-3 receptor (MC3R) helps regulate energy homeostasis and mice lacking MC3R have increased fat mass and reduced lean mass. Therefore, agonists that selectively activate MC3R might have beneficial effects related to weight gain and glucose metabolism. This assay consists of a 96-well plate coated with a transfection complex containing DNA constructs for MC3R...
Application: Reverse transfection reporter assay
500.00€
Review
Melanocortin-4 Receptor Reporter Assay Kit
Melanocortin-4 Receptor Reporter Assay Kit

Item number: Cay600190-100

The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and inflammation. Mice deficient in MC4R have increased lipid deposition associated with elevated adiposity, while mutations in MC4R in humans are associated with early onset or severe obesity. This assay consists of a 96-well plate coated with a transfection complex containing DNA...
Application: Reverse transfection reporter assay
500.00€
Review
Orexin Receptor 1 STEP(TM) Reporter Assay Kit (Luminescence)
Orexin Receptor 1 STEP(TM) Reporter Assay Kit...

Item number: Cay600240-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 1 Receptor (OX1R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with both OX1R and Secretory Alkaline Phosphatase (SEAP) reporter...
Application: OX1R activation assays
Format: Homog.
500.00€
Review
Orexin 2 Receptor Reporter Assay Kit
Orexin 2 Receptor Reporter Assay Kit

Item number: Cay600250-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 2 Receptor (OX2R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with both OX2R and Secretory Alkaline Phosphatase (SEAP) reporter...
Application: OX2R activation assays
Format: Homog.
500.00€
Review
Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence)
Secreted Alkaline Phosphatase Reporter Gene...

Item number: Cay600260-300

Secreted alkaline phosphatase (SEAP) is commonly used as a reporter of gene expression. Compared to other conventional intracellular reporters such as chloramphenicol acetyltransferase (CAT) and firefly luciferase, SEAP has the advantage of being secreted from transfected cells into the culture medium. Cayman's Secreted Alkaline Phosphatase Reporter Gene Assay Kit...
Application: Chemiluminescence
Format: Homog.
287.00€
Review
EP2 Receptor (rat) Reporter Assay Kit
EP2 Receptor (rat) Reporter Assay Kit

Item number: Cay600340-1

The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases. Cayman's EP2 Receptor (rat) Reporter Assay Kit consists of a 96-well plate...
Application: Reverse transfection reporter assay
Reactivity: Rat
Format: Homog.
500.00€
Review
EP4 Receptor (rat) Reporter Assay Kit
EP4 Receptor (rat) Reporter Assay Kit

Item number: Cay600350-100

The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases. Cayman's EP4 Receptor (rat) Reporter Assay Kit consists...
Application: Reverse transfection reporter assay
Reactivity: Rat
Format: Homog.
500.00€
Review
CYP1A1/2 Induction Reporter Assay Kit
CYP1A1/2 Induction Reporter Assay Kit

Item number: Cay600670-100

Early screening of a drug candidate's potential to induce or inhibit CYP1A1/2 is a critical step in the drug development process. Cayman's CYP1A1/2 Induction Reporter Assay Kit is a novel method to assess CYP1A2 induction. Our Reverse Transfection Reporter Assays have overcome many of the disadvantages of other transfection approaches. Cayman's CYP1A1/2 Induction Reporter...
Application: Reverse transfection reporter assay
Format: Solid Phase
500.00€
Review
CYP2B6 Induction Reporter Assay Kit
CYP2B6 Induction Reporter Assay Kit

Item number: Cay600680-100

Early screening of a drug candidate's potential to induce or inhibit CYP2B6 is a critical step in the drug development process. Cayman's CYP2B6 Induction Reporter Assay Kit is a novel method to evaluate human Constitutive Androstane Receptor 3 (hCAR3)-mediated CYP2B6 induction for the discovery of hepatic CYP inducers. Our Reverse Transfection Reporter Assays have overcome...
Application: Reverse transfection reporter assay
Format: Solid Phase
500.00€
Review
CYP2C9 Induction Reporter Assay Kit
CYP2C9 Induction Reporter Assay Kit

Item number: Cay601120-1

Early screening of drug candidate's potential to induce or inhibit CYP2C9 is a critical step in the drug development process. The CYP2C9 Induction Reporter Assay Kit is a novel method to evaluate CYP2C9 induction by drug candidates. Cayman's CYP2C9 Induction Reporter Assay Kit consists of a 96-well plate coated with a transfection complex containing a Secreted Alkaline...
Application: Reverse transfection reporter assay
Format: Solid Phase
500.00€
Review
FFAR1 (GPR40) Reporter Assay Kit
FFAR1 (GPR40) Reporter Assay Kit

Item number: Cay601190-1

Free fatty acid receptor 1 (FFAR1)/GPR40 is a G protein-coupled receptor for long-chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of insulin release from pancreatic beta cells and mediates triglyceride-induced secretion of incretins GLP-1 and GIP from intestinal endocrine cells. Cayman's FFAR1...
Application: Cell based assays, HTS, Reverse transfection reporter assay
Reactivity: Human
Format: Solid Phase
500.00€
Review
FFAR4 (GPR120) Reporter Assay Kit
FFAR4 (GPR120) Reporter Assay Kit

Item number: Cay601200-1

Free fatty acid receptor 4 (FFAR4)/GPR120 is a G protein-coupled receptor for long chain fatty acids such as docosahexaenoic acid and eicosapentaenoic acid omega-3 fatty acids. It is involved in the regulation of glucose uptake in adipocytes and mediates anti-inflammatory activity in macrophages. Cayman's FFAR4 (GPR120) Reporter Assay Kit consists of a 96-well plate coated...
Application: Cell based assays, HTS, Reverse transfection reporter assay
Reactivity: Human
Format: Solid Phase
500.00€
Review
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