Apoptosis and Cell Cycle Assays

DNA fragmentation represents a characteristic of late stage apoptosis. DNA fragmentation in apoptotic cells can be detected by terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL). The TUNEL assay relies on the presence of nicks in the DNA which can be identified by TdT, an enzyme that...

This kit makes use of an injectable green fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. It is an ideal reagent to asses the efficacy of chemotherapy in animals.

This kit makes use of an injectable green fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. It is an ideal reagent to asses the efficacy of chemotherapy in animals.

This kit makes use of an injectable red fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. Ideal reagent to asses the efficacy of chemotherapy.

One of the hallmarks of the early stages of apoptosis is the redistribution of membrane phospholipids such as phosphatidylserine and phosphatidylethanolamine from the inner to outer leaflet of the membrane bilayer where they are exposed on the cell surface. Externalization of phosphatidylserine residues to the outer...

This kits makes use of a cell-permeant green fluorecent probe (FAM-VAD-FMK ) that binds to all active caspases in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

This kits makes use of a cell-permeant green fluorecent probe (FAM-LETD-FMK ) that binds to active caspase-8 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

MitoPT(TM)-TMRE Depolarization Detection Kits can evaluate apoptosis using flow cytometry, fluorescence microscopy, or a fluorometric plate reader.

MitoPT(TM)-TMRM Depolarization Detection Kits can evaluate apoptosis using flow cytometry, fluorescence microscopy, or a fluorometric plate reader.

The red FLICA® 660-VAD-FMK caspase detection probe is comprised of the preferred affinity peptide sequence (VAD) targeted by activated pan-caspases, a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK) reactive moiety. The resulting fluorescent caspase inhibitor probe forms an irreversible, covalent...

Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...

The far-red FLICA® 660-DEVD-FMK caspase-3 detection probe is comprised of the preferred affinity peptide sequence (DEVD) targeted by activated caspase-3 and caspase-7, a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK) reactive moiety. The resulting fluorescent caspase-3 inhibitor probe forms an...