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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
M2352-03A.100 | 100 µl | - | - |
3 - 19 business days* |
780.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The p38 family refers to the SAPK2/3 Kinases (Stess-Activated Protein Kinases), a subfamily of... more
Product information "Anti-phospho-MAP Kinase p38 alpha, (Thr180/Tyr182) (mitogen-activated protein kinase 14, Cytokine su"
The p38 family refers to the SAPK2/3 Kinases (Stess-Activated Protein Kinases), a subfamily of JNK/SAPK family. p38/SAPK Kinases are also activated by stresses, most notably inflammatory cytokines, irradiation, and certain toxins such as anisomycin and arsenite. SAPKs have been implicated in many pathological conditions, including inflammation, cancer and neurodegenerative diseases. As with the other MAPK family members (ERK, JNK, p38MAPK, and ERK5), p38 is activated through phosphorylation on both threonine and tyrosine residues at the Thr-X-Tyr dual phosphorylation motif, where X is Gly for p38. Once phosphorylated and active, it then goes on to phosphorylate downstream targets in both the cytoplasm and the nucleus. Some of their main targets of p38 are the kinase MAPKAPK2 and the transcription factor ATF2 that are activated via their phosphorylation. Applications: Suitable for use in Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilution: Western Blot: 1:5000-1:10,000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | EC=2.7.11.24, Anti-phospho-CSBP, Anti-phospho-MAPK14, Anti-phospho-SAPK2a, Anti-phospho-MAPK 14, Anti-phospho-MAP kinase 14, Anti-phospho-MAP kinase MXI2, Anti-phospho-MAP kinase p38 alpha, Anti-phospho-CSAID-binding protein |
Supplier: | United States Biological |
Supplier-Nr: | M2352-03A |
Properties
Application: | IF, WB |
Antibody Type: | Monoclonal |
Clone: | 9H254 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to amino acids surrounding and including phosphorylated Thr180/Tyr182 of human p38 alpha. |
Format: | Supernatant |
Database Information
KEGG ID : | K04441 | Matching products |
UniProt ID : | Q16539 | Matching products |
Gene ID | GeneID 1432 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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