271 products were found matching "K04441"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Dog MAPK14. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Dog MAPK14. Next,...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. MAPK12 functions as a signal transducer during differentiation of...

In 1X PBS, pH 7.4, with 0.09% sodium azide. MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is...

AZD 7624 is an inhibitor of p38alpha MAPK signaling. AZD 7624 (1 µM), in combination with the synthetic glucocorticoid dexamethasone (Cay-11015), prevents LPS-induced increases in the levels of TNF-alpha and IL-6 secreted from primary human alveolar macrophages isolated from patients with chronic obstructive...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAPK14. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAPK14....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAPK13. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAPK13....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAPK12. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAPK12....

Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...

Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.

SB-203580 is an inhibitor of p38 MAPK that exhibits immunostimulatory, anticancer, and anti-fibrotic activities. In peripheral blood mononuclear cells, SB-203580 increases secretion of IFN- . In lung epithelial cells, SB-203580 inhibits TGB- 1-induced epithelial-to-mesenchymal transition (EMT). Additionally,...

Mxi2 is a splice variant of SAPK2alpha (p38). Recognizes the N-terminus of human, mouse, rat and dog p38 splice variant Mxi2.

SB 239063 is a selective p38 MAPK inhibitor (IC50 = 44 nM for recombinant purified p38alpha). It displays greater than 220-fold selectivity for p38 MAPK over ERK, JNK1, and other kinases. SB 239063 has been shown to reduce inflammatory cytokine production in lipopolysaccharide-stimulated human peripheral blood...