Product information "Anti-ZC3H8, NT (ZC3H8, ZC3HDC8, Zinc finger CCCH domain-containing protein 8) (Azide free) (APC)"
Protein function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. [The UniProt Consortium]
Anti-ZC3H8, Anti-ZC3HDC8, Anti-Zinc finger CCCH domain-containing protein 8