Anti-ZC3H8

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-089A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A303-089A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific... more

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Product information "Anti-ZC3H8"

Protein function: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. [The UniProt Consortium]

Keywords:	Anti-ZC3H8, Anti-ZC3HDC8, Anti-Zinc finger CCCH domain-containing protein 8
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-089A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A303-089A-T maps to a region between residue 1 and 50 of human Znc Finger CCCH-type Containing 8 using the numbering given in entry NP_115883.2 (GeneID 84524).
Format:	Antigen Affinity Purified