Anti-Wnt3a (Wingless-type MMTV (mouse mammary tumor virus) integration site family member)

Anti-Wnt3a (Wingless-type MMTV (mouse mammary tumor virus) integration site family member)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
W3011-02C.100 100 µl - -

3 - 19 business days

505.00€
 
The Wnt family includes several secreted glycoproteins that play important roles in animal... more
Product information "Anti-Wnt3a (Wingless-type MMTV (mouse mammary tumor virus) integration site family member)"
The Wnt family includes several secreted glycoproteins that play important roles in animal development (1). There are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteins (2). Wnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathways (3). The canonical Wnt/beta-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor family (4). Aberrant activation of Wnt signaling pathways is involved in several types of cancers (5). Wnt3a protein is palmitoylated and can function as a growth factor for hematopoietic stem cells (6). Although functionally distinct, Wnt3a shows high homology to Wnt3 (7). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot (transfected): 1:1000. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Protein Wnt-3a
Supplier: United States Biological
Supplier-Nr: W3011-02C

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Mouse
Immunogen: Synthetic peptide (KLH-coupled) corresponding to residues surrounding Asp294 of human Wnt3a. Epitope: CentralMolecular Weight: ~42kD
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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