Anti-VEGI / TL1A, clone VEGI/1283

Anti-VEGI / TL1A, clone VEGI/1283
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3348-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3348-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. TNF ligand-related... more
Product information "Anti-VEGI / TL1A, clone VEGI/1283"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer. Protein function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [The UniProt Consortium]
Keywords: Anti-TL1, Anti-TNFSF15, VEGI / TL1A Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3348-20UG

Properties

Application: WB, FC, IF, IHC
Antibody Type: Monoclonal
Clone: VEGI/1283
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A full length human recombinant protein was used as the immunogen for this TL1A antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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