Anti-TSC2 / Tuberin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40418.100	100 µl		-	-	6 - 14 business days*		624.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or... more

Close menu

Product information "Anti-TSC2 / Tuberin"

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, PubMed:28215400). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1 (PubMed:15340059). May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5. [The UniProt Consortium]

Keywords:	Anti-TSC4, Anti-TSC2, Anti-Tuberin, Anti-Tuberous sclerosis 2 protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40418

Properties

Application:	FC, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human Tuberin
MW:	200 kD
Format:	Affinity Purified