123 products were found matching "K07207"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is...

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase...

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (PubMed:12271141, PubMed:28215400). Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct...

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase...

Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase...

Anti-TSLP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSLP from other sources has not been determined. Protein function: In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by...

Anti-TSLP Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSLP from other sources has not been determined. Protein function: In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin, is human protein. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tuberous sclerosis 2, also known as TSC2 or Tuberin is a protein that is in humans. Mutations in this gene lead to tuberous sclerosis complex. TSC2 is believed to be a tumor suppressor and is able to stimulate specific GTPases. It associates with hamartin in a...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative...