Anti-TPMT

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA019851.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA019851.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Catalyzes the S-methylation of thiopurine drugs such as 6- mercaptopurine (also... more

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Product information "Anti-TPMT"

Protein function: Catalyzes the S-methylation of thiopurine drugs such as 6- mercaptopurine (also called mercaptopurine, 6-MP or its brand name Purinethol) and 6-thioguanine (also called tioguanine or 6-TG) using S- adenosyl-L-methionine as the methyl donor (PubMed:657528, PubMed:18484748). TPMT activity modulates the cytotoxic effects of thiopurine prodrugs. A natural substrate for this enzyme has yet to be identified. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 71% and to rat: 68%

Keywords:	Anti-TPMT, Anti-Thiopurine methyltransferase, Anti-Thiopurine S-methyltransferase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA019851

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ALVAINPGDR KCYADTMFSL LGKKFQYLLC VLSYDPTKHP GPPFYVPHAE IERLFGKICN IRCLEKVDAF EERHKSWGID CL (ATA-APrEST73837)