Anti-TNIK

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA012128.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA012128.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Serine/threonine kinase that acts as an essential activator of the Wnt... more

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Product information "Anti-TNIK"

Protein function: Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N- terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 99% and to rat: 99%

Keywords:	Anti-TNIK, Anti-KIAA0551, EC=2.7.11.1, Anti-TRAF2 and NCK-interacting protein kinase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA012128

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: QGPALTASQS VHEQPTKGLS GFQEALNVTS HRVEMPRQNS DPTSENPPLP TRIEKFDRSS WLRQEEDIPP KVPQRTTSIS PALARKNSPG NGSALGPRLG SQPIRASNPD LRRTEPILES PLQRTSSGSS SSSS (ATA-APrEST71436)