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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
T8050-34B.100 | 100 µg | - | - |
3 - 19 business days* |
878.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
TLRs belong to a family of proteins that specifically recognize and sense microbial products.... more
Product information "Anti-TLR4 (Toll-like Receptor 4, hToll, CD284, ARMD10)"
TLRs belong to a family of proteins that specifically recognize and sense microbial products. They are highly conserved throughout evolution. In Drosophila, toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defences. TLRs identified as type I transmembrane signalling receptors act as innate immune recognition receptors against many pathogens. TLR4 is a functional receptor for gram-negative bacterial lipopolysaccharides (LPS). TLR4 associates with MD-2 which is absolutely required for LPS-induced activation of TLR4. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to LPS of Gram-negative bacteria. This monoclonal antibody is a TLR4 function-blocking antibody that is useful for studies on the role of TLR4 as a receptor for LPS induced cytokine production by TLR4 bearing cells. Applications: Suitable for use in Flow Cytometry and Functional Studies. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-TLR4, Anti-CD284, Anti-hToll, Anti-Toll-like receptor 4 |
Supplier: | United States Biological |
Supplier-Nr: | T8050-34B |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 13A80 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | TLR4/MD-2 expressing CHO cells/ chimeric TLR4/MD-2 fusion protein |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10160 | Matching products |
UniProt ID : | O00206 | Matching products |
Gene ID | GeneID 7099 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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