Anti-Thromboxane synthase

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
G-CAB5173.50	50 µl		-	-	9 - 20 business days*		352.00€
G-CAB5173.100	100 µl		-		9 - 20 business days*		448.00€

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Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a... more

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Product information "Anti-Thromboxane synthase"

Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:8436233, PubMed:11297515, PubMed:9873013, PubMed:11097184, PubMed:24009185, PubMed:22735388). Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12- HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2 (PubMed:11297515, PubMed:9873013, PubMed:22735388). Additionally, displays dehydratase activity, toward (15S)-hydroperoxy- (5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE (PubMed:17459323). [The UniProt Consortium]

Keywords:	Anti-TXS, Anti-CYP5, Anti-TBXAS1, Anti-TXA synthase, Anti-Cytochrome P450 5A1, Anti-Thromboxane-A synthase, Anti-Hydroperoxy icosatetraenoate dehydratase, Thromboxane synthase Rabbit mAb
Supplier:	Assay Genie
Supplier-Nr:	CAB5173

Properties

Application:	WB
Antibody Type:	Monoclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse

Database Information

KEGG ID :	K01832 \| Matching products
UniProt ID :	P24557 \| Matching products
Gene ID	GeneID 6916 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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