41 products were found matching "K01832"!

Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. TBXAS1 antibody detects Thromboxane-A synthase 1, encoded by the TBXAS1 gene on chromosome 7q34. TBXAS1 antibody is used to study this cytochrome P450 enzyme responsible for producing thromboxane A2 from prostaglandin H2. Thromboxane A2 is a...

Thromboxane (TX) synthase catalyzes the conversion of prostaglandin H2 to TXA2, which is a potent vasoconstrictor and inducer of platelet aggregation. The enzyme has been cloned from a variety of species including human, pig, rat, and mouse and has a molecular weight of approximately 60,000. Northern blot analysis...

Furegrelate is a potent inhibitor of thromboxane synthase with little effect on other enzymes essential for arachidonate metabolism. The IC50 value is 15 nM for human platelet microsomal thromboxane synthase.Formal Name: 5-(3-pyridinylmethyl)-2-benzofurancarboxylic acid, sodium salt. CAS Number: 85666-17-7....

Inhibition of thromboxane synthase (TXAS), especially in human platelets, has been a clinical objective for many years. 1-Alkyl (N-alkyl)-imidazole derivatives have been recognized as TXAS inhibitors since the early 1980s. Ozagrel is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXAS with an...

Pinane thromboxane A2 (PTA2) is a stable analog of TXA2. It is a TP receptor antagonist and an inhibitor of thromboxane synthase. PTA2 inhibits U-46619-induced cat coronary artery constriction (ID50 = 0.1 µM), U-46619-induced aggregation of human platelets (IC50 = 2 µM), and rabbit platelet thromboxane synthase...

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily...

1-Benzylimidazole is a selective inhibitor of thromboxane synthase. It reduces TXB2 levels and increases blood flow in ischemia-reperfusion injury of rat brain.Formal Name: 1-(phenylmethyl)-1H-imidazole. CAS Number: 4238-71-5. Molecular Formula: C10H10N2. Formula Weight: 158.2. Purity: >95%. Formulation: (Request...

Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:8436233, PubMed:11297515, PubMed:9873013, PubMed:11097184, PubMed:24009185, PubMed:22735388). Cleaves also PGH2 to...

Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:8436233, PubMed:11297515, PubMed:9873013, PubMed:11097184, PubMed:24009185, PubMed:22735388). Cleaves also PGH2 to...

Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:8436233, PubMed:11297515, PubMed:9873013, PubMed:11097184, PubMed:24009185, PubMed:22735388). Cleaves also PGH2 to...