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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
T5050-50B.100 | 100 tests | - | - |
3 - 19 business days* |
825.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Thrombopoietin receptor (Tpo R), also known as myeloproliferative leukemia protein (c-mpl), is a... more
Product information "Anti-Thrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene c-Mpl, CD11"
Thrombopoietin receptor (Tpo R), also known as myeloproliferative leukemia protein (c-mpl), is a 95kD type I transmembrane protein that is a member of the type I cytokine receptor family within the hematopoietin/cytokine receptor superfamily. The 635aa full-length human Tpo R contains a 25aa signal sequence, a 466aa extracellular domain with a ligand binding domain and two fibronectin type III domains, a transmembrane (TM) domain and a cytoplasmic domain. The extracellular domain of human Tpo R shares 78%, 76%, 81%, 82% and 80% aa identity with mouse, rat, cow, dog, and horse, respectively. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 10ul labels 1x10e6 cells using TF-1 human erythroleukemic cell line., Optimal dilutions to be determined by the researcher. Flow Cytometry: 1. TF-1 cells may be Fc-blocked with 1ug of human IgG/10e5 cells for 15 minutes at RT. Do not wash excess blocking IgG from this reaction., 2. After blocking, 10ul of T5050-50B was added to up to 1x10e6 cells and incubated for 30 minutes at RT. , 3. Unbound antibody was removed by washing the cells twice in F4568-10: Flow Cytometry Staining Buffer., Note: whole blood requires a RBC lysis step at this point., 4. The cells were resuspended in Flow Cytometry Staining Buffer for final flow cytometric analysis. As a control for this analysis, cells in a separate tube should be treated with PE-labeled rmouse IgG2a antibody. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Keywords: | Anti-Thrombopoietin receptor, Anti-Myeloproliferative leukemia protein |
Supplier: | United States Biological |
Supplier-Nr: | T5050-50B |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 11D72 |
Conjugate: | Phycoerythrin |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to human Thrombopoetin receptor expressed in NSO cells (P40238). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05082 | Matching products |
UniProt ID : | P40238 | Matching products |
Gene ID | GeneID 4352 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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