Anti-TBXAS1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA031258.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA031258.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a... more

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Product information "Anti-TBXAS1"

Protein function: Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation (PubMed:8436233, PubMed:11297515, PubMed:9873013, PubMed:11097184, PubMed:24009185, PubMed:22735388). Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12- HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2 (PubMed:11297515, PubMed:9873013, PubMed:22735388). Additionally, displays dehydratase activity, toward (15S)-hydroperoxy- (5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE (PubMed:17459323). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 85%

Keywords:	Anti-TXS, Anti-CYP5, Anti-TBXAS1, Anti-TXA synthase, Anti-Cytochrome P450 5A1, Anti-Thromboxane-A synthase, Anti-Hydroperoxy icosatetraenoate dehydratase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA031258

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PDCQEKLLRE VDVFKEKHMA PEFCSLEEGL PYLDMVIAET LRMYPPAFRF TREAAQDCEV LGQRIPAGAV LEMAVGALHH DPEH (ATA-APrEST78416)