Anti-SSTR2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA007264.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA007264.100	100 µl		-		7 - 10 business days*		421.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis... more

Close menu

Product information "Anti-SSTR2"

Protein function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 96%

Keywords:	Anti-SS2R, Anti-SSTR2, Anti-SS2-R, Anti-SRIF-1, Anti-SS-2-R, Anti-Somatostatin receptor type 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA007264

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DNFKKSFQNV LCLVKVSGTD DGERSDSKQD KSRLNETTET QRTLLNGDLQ TSI (ATA-APrEST70183)