Anti-SMAD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F53216-0.08ML	80 µl		-	-	3 - 10 business days*		326.00€
NSJ-F53216-0.4ML	400 µl		-	-	3 - 10 business days*		702.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

In 1X PBS, pH 7.4, with 0.09% sodium azide. SMAD2 is a receptor-regulated SMAD (R-SMAD) that is... more

Close menu

Product information "Anti-SMAD2"

In 1X PBS, pH 7.4, with 0.09% sodium azide. SMAD2 is a receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [UniProt] Protein function: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]

Keywords:	Anti-SMAD2, Anti-Smad2, Anti-MADH2, Anti-JV18-1, Anti-hMAD-2, Anti-hSMAD2, Anti-SMAD 2, Anti-MAD homolog 2, Anti-SMAD family member 2, Anti-Mad-related protein 2, Anti-Mothers against DPP homolog 2, Anti-Mothers against decapentaplegic homolog 2, SMAD2 An
Supplier:	NSJ Bioreagents
Supplier-Nr:	F53216

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse
Immunogen:	This SMAD2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 106-140 amino acids from the N-terminal region of human SMAD2.
Format:	Purified