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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG59129.50 | 50 µg | - | - |
6 - 14 business days* |
520.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Splicing factor that specifically promotes exon- inclusion during alternative... more
Product information "Anti-SFRS3 / SRSF3"
Protein function: Splicing factor that specifically promotes exon- inclusion during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937). Also functions as export adapter involved in mRNA nuclear export (PubMed:11336712, PubMed:18364396, PubMed:28984244). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity (PubMed:11336712, PubMed:18364396). Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export (PubMed:28984244). RNA-binding is semi-sequence specific (PubMed:17036044). [The UniProt Consortium]
Keywords: | Anti-SRSF3, Anti-SFRS3, Anti-Pre-mRNA-splicing factor SRP20, Anti-Serine/arginine-rich splicing factor 3, Anti-Splicing factor, arginine/serine-rich 3 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG59129 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat (Expected: hamster) |
Immunogen: | Synthetic peptide corresponding to aa. 1-29 of Human SFRS3 / SRSF3. (MHRDSCPLDCKVYVGNLGNNGNKTELERA) |
MW: | 19 kD |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12892 | Matching products |
UniProt ID : | P84103 | Matching products |
Gene ID | GeneID 6428 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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