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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F44057-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F44057-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a member of the runt... more
Product information "Anti-RUNX3"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Protein function: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). [The UniProt Consortium]
Keywords: | Anti-AML2, Anti-RUNX3, Anti-CBF-alpha-3, Anti-PEA2-alpha C, Anti-PEBP2-alpha C, Anti-Oncogene AML-2, Anti-Acute myeloid leukemia 2 protein, Anti-Runt-related transcription factor 3, Anti-Core-binding factor subunit alpha-3, RUNX3 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F44057 |
Properties
Application: | IHC, IF, WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 168-197 from the human protein was used as the immunogen for this RUNX3 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K09279 | Matching products |
UniProt ID : | Q13761 | Matching products |
Gene ID | GeneID 864 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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