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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-N1190-25UG | 25 µg | - | - |
3 - 10 business days* |
317.00€
|
||
NSJ-N1190-100UG | 100 µg | - | - |
3 - 10 business days* |
622.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Runt family of transcription... more
Product information "Anti-RUNX3, clone RNX864"
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells. Protein function: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). [The UniProt Consortium]
Keywords: | Anti-AML2, Anti-RUNX3, Anti-CBF-alpha-3, Anti-PEA2-alpha C, Anti-PEBP2-alpha C, Anti-Oncogene AML-2, Anti-Acute myeloid leukemia 2 protein, Anti-Core-binding factor subunit alpha-3, Anti-Runt-related transcription factor 3, RUNX3 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | N1190 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | RNX864 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A RUNX3 recombinant protein fragment was used as the immunogen for this antibody. |
Format: | Purified |
Database Information
KEGG ID : | K09279 | Matching products |
UniProt ID : | Q13761 | Matching products |
Gene ID | GeneID 864 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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