Anti-ROS1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55598.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell... more

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Product information "Anti-ROS1"

Protein function: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2. [The UniProt Consortium]

Keywords:	Anti-MCF3, Anti-ROS1, EC=2.7.10.1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine kinase, Anti-Receptor tyrosine kinase c-ros oncogene 1, Anti-Proto-oncogene tyrosine-protein kinase ROS
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55598

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	KLH-conjugated synthetic peptide around aa. 1744-1777 (C-terminus) of Human ROS1
Format:	Purified