- Search results for K05088
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35 products were found matching "K05088"!
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Item number: NSJ-F54089-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival...
Keywords: | Anti-MCF3, Anti-ROS1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine kinase,... |
Application: | WB |
Host: | Mouse |
Species reactivity: | human |
From 326.00€
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Item number: ELK-ELK5050.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ROS1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ROS1. Next,...
Keywords: | MCF3, ROS1, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, c-Ros receptor tyrosine kinase, Receptor tyrosine kinase c-ros... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: ELK-ELK7244.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ROS1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ROS1. Next,...
Keywords: | Ros1, EC=2.7.10.1, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, c-Ros receptor tyrosine kinase, Receptor tyrosine kinase... |
Application: | ELISA |
Species reactivity: | rat |
From 365.00€
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Item number: BPS-78189
The ROS1 Kinase Assay Kit is designed to measure ROS1 activity for screening and profiling applications using Kinase-Glo(R) MAX as a detection reagent. The signal is measured using a luminometer or a microplate reader capable of reading chemiluminescence.
Keywords: | ROS, c-Ros Oncogene 1, MCF3, MCF3 kit, ROS kit, ROS assay kit, MCF3 assay kit, |
Application: | Enzyme kinetics, drug discovery, HTS |
Species reactivity: | human |
789.00€
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Item number: Cay23397-1
TPX-0005 is a multi-kinase inhibitor that inhibits TrkA, TrkB, and TrkC (IC50s = 0.83, 0.05, and 0.1 nM, respectively) as well as C-ros oncogene 1 (ROS1, IC50 = 0.07 nM). It inhibits a variety of other kinases, including ALK, JAK2, LYN, Src, and FAK (IC50s = 1.04, 1.04, 1.66, 5.3, and 6.96 nM, respectively). It...
Keywords: | (7S,13R)-11-fluoro-6,7,13,14-tetrahydro-7,13-dimethyl-1,15-etheno-1H-pyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4... |
Application: | ATP-competitive ALK/ROS1/TRK inhibitor |
CAS | 1802220-02-5 |
MW: | 355.4 D |
From 43.00€
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Item number: ARG55598.100
Protein function: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR...
Keywords: | Anti-MCF3, Anti-ROS1, EC=2.7.10.1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
584.00€
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Item number: BPS-40268
Human Proto-oncogene c-Ros-1 (ROS1), also known as MCF3, GenBank Accession No. NM_002944), amino acids 1883-2347(end) with N-terminal GST-tag, MW= 78 kDa, expressed in Sf9 cells via a baculovirus expression system. Specific Activity is 8 pmole/min/µg.
Keywords: | ROS1, MCF3, Proto-oncogene c-Ros, Proto-oncogene c-Ros-1, c-Ros receptor tyrosine kinase, Receptor tyrosine kinase c-ros... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Baculovirus |
Origin: | human |
MW: | 65 kD |
540.00€
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Item number: Cay18491-5
ASP3026 is an inhibitor of anaplastic lymphoma kinase (ALK, IC50s = 3.5, 10, and 5.4 nM for the wild-type, ALKF1174L, and ALKR1275Q enzymes, respectively). It is selective for ALK over a panel of 86 kinases at 1,000 nM but also inhibits c-Ros oncogene 1 (ROS1) and tyrosine kinase non-receptor 2 (TNK2, IC50s = 8.9...
Keywords: | N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4... |
Application: | ALK / ACK inhibitor |
CAS | 1097917-15-1 |
MW: | 580.7 D |
From 53.00€
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Item number: NSJ-F52830-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival...
Keywords: | Anti-MCF3, Anti-ROS1, EC=2.7.10.1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: Cay18371-10
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that promotes cell proliferation and blocks apoptosis. PF-06463922 is an ATP-competitive, selective inhibitor of ALK (Ki = i = 0.7 nM). It has strong activity against all known ALK and ROS1 mutants identified in patients, including the EML4-L1196M mutant...
Keywords: | Lorlatinib,... |
Application: | ALK / ROS1 inhibitor |
CAS | 1454846-35-5 |
MW: | 406.4 D |
From 50.00€
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Item number: E-AB-12856.120
This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor...
Keywords: | Anti-MCF3, Anti-ROS1, EC=2.7.10.1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 71.00€
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Item number: G-CAB16669.100
WB 1:500 - 1:2000. Protein function: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including...
Keywords: | Anti-ROS1, Anti-MCF3, EC=2.7.10.1, Anti-Proto-oncogene c-Ros, Anti-Proto-oncogene c-Ros-1, Anti-c-Ros receptor tyrosine... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 352.00€
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